Two groups of neurotic outpatients were compared in their outcome afterfrontal EMG biofeedback treatment with Jacobson progressive relaxation at home.The firstneurotic group consisted of 42 patients and treated once every two days for four weeks whilethe second group consisted of 19 cases and treated every day but for only two weeks.Similarily satisfactory clinical effects and same trends of change in various physiological indexof EMG and clinical symptons were observed,between these two groups.No relationship wasfound between patient's personality characteristc and clinical effects.In a four follow up,2/3patients reported a continuous satisfactory outcome.

Objective To investigate the freatment outcome of internal fixation of the metacarpal and phalanx fracture using the pure fitanium mini plate.Methods 42 cases(78 lesions) of metacarpal and phalanx fracture were involved.Internal fixation with custom made pur titanium mini plate was done.Results Postoperative follow up rauged from 3 to 14 months and the fracture was healed in 42 cases.The bone union of roantgenographic eridence was 6 to 12 weeks.According to the functional evaluation of TAM ascles the excellent and good rate was 85.7%.Conclusion The AO mini-plate in treatment of the metacarpal and phalax fracture has a firm fixation.It is an optimal strategy for metarcarpal and phalanx fracture.

Adenosine is an endogenous purine uncleoside released by cells as part of the normal metablic mechinary. During inflammation, massive ATP degradation increases the local adenosine concentration to the micromolar range, at the range, adenosine extert potent antiinflammatory rale. In vivo or in vitro experiments, the addition exogenious adenosine, its analogues and inhibition of its degradation attenuate injury of animal models of inflammation. Antiinflammatory mechinasms involve in;(1)Adenosine inhibites neutrophil function in vitro, including chemotaxiz, adhesion, phogocytosis, and oxygen radical generation. (2) Decrease the expression of collagenase, and reduce the amount of collagenase. (3)Blocking neutrophil adhesion to the endothelium mediated by L-selectin and ftrEategrin. (4)inhibition activated humanmonocytes and macrophage secreting cytokins. (5) Adenosine enhances IL-10 secretion by human monocytes. (6)inhibition of immune response and so on. Relation with nonsteroidal antiinflammatory drugs (NSALDs) includes:(1)MTX and SASP inhibit the activity of 5-aminoimidazole-4-carboxam-ide ribonucleotide (AICAR) transformylase resulting in increased local adenosine concentraton. (2) Azathioprine and its potential metabolite inhibits adenosine kinase, diminish AMP formation by adenosine. In conclusion, the existance of a novel class of antiinflammatory agents, affects adenosine metabolism and may be a useful antiinflammatory drug as well.

Sulfonylureas are one of the major oral drugs for the treatment of type 2 diabetes mellitus.Studies in recent years have shown that such drugs have the effect of independent of reducing blood sugar on ischemic stroke.This effect is mainly associated with the combination of sulfonylurea receptor 1 (SUR1) to regulate of ATP-sensitive non-selective cation channels.

Objective To study the mechanism of toxicity of methylmercury on primary cultured SD rat astrocyte.Methods Treat primary cultured SD rat astrocyte with methylmercury.Determine the level of cyto-oxidation redoxin with High Performance Liquid Chromatography(HPLC).Western-blot was applied to examine the protein expression of nuclear factor erythroid 2 related factor 2(Nrf2).Results With the increase of the concentration of methylmercury,the redoxin level of astrocyte was apparently decreasing.When the concentration of methylmercury was at a low level,the expression of Nrf2 was increasing with the increase of the methylmercury concentration.When the concentration of methylmercury was at a high level,the expression of Nrf2 was decreasing with the increase of the methylmercury concentration.Conclusion The toxicity of methylmercury on primary cultured SD rat astrocyte can be realized through altering the function of GSH and Nrf2.

Objective Discuss the active mechanism of dural border layer cells in the process of subdural fluid collection developing into chronic subdural hematoma.Methods Review and analyse literature combined with one special return case whom with subdural fluid collection.Results At the same case,subdural fluid collection at left side did no change during 49 months,and that at right side developed into chronic subdural hematoma in 23rd week,and the latter was absorbed at 62rd week.Conclusion In the process of subdural fluid collection developing into chronic subdural hematoma,dural border layer cells roll on important functions.

Objective:To understand the sleep duration, sleep habits, the prevalence rate of sleep problem and its related factors on the children range from 4 to 12 years old. Methods:The parents of 727 children range from 4 to 12 years old were asked to answer The Children's Sleep Habits Questionnaire (CSHQ) and the general information forms, which were used to rate their children.Results:The average sleep time on bed of the children was 9.6?0.9 hours, with no difference between males and females. The total scores of CSHQ were 36.8?13.6, and the prevalence of sleep problem was 31.0%. The total scores of CSHQ among 4-6 years old group, 7-9 years old group and 10-12 years old group were significant different (42.4?14.1?34.9?12?31.8?12, respectively ;P

Objective : To investigate the incidence of Restless Legs Syndrome (RLS) in pregnant women and the effect of the RLS on the sleep quality of the women during pregnancy. Methods: 113 pregnant women were evaluated by using International RLS Scale, PSQI (Pittsburg Sleep Quality Inventory). Results: The prevalence of RLS in pregnant women in the outpatient department was 12.4% (14/113), the percentage of RLS pregnant women with PSQI total score higher than 7 was 28.6%, and that was 10.1% in the pregnant women without RLS (x2 =3.86,P

0.05).Conclusions: (1) The more severe of learning stress, the higher level of PMDD. (2) There was no difference in anxiety and depression between the students who suffered from PMDD and the who didn't. (3) The students who suffered from PMDD had more psychosomatic symptoms.

Objective To find out the effect of NO on the stroke of periodic paralysis.Methods Blood potassium,NO and NOS were measured in patients with hypokalemic periodic paralysis during paralysis stroke and after muscle power recovered.The relationship between NO and NOS and paralysis in the different phase was observed.Results NO and NOS decreased obviously in the phase of paralysis,which tended to be normal with recovering of blood potassium and muscle power after treatment.The change of NO was positively correlated with the decreasing degree of blood potassium(r=0.3511,P