Objective To observe the influence of inactive FRMD4A gene′s expression on the biological behavior of tongue cancer CAL-27cell. Methods FRMD4A-siRNA was transfered into CAL-27 cell by lipidosome, to the expression of FRMD4A-siRNA in CAL-27 cell after transfection was detect by qRT-PCR cell proliferation , was checked by CCK-8,the influence of inactive FRMD4A gene on cell cycle distribution of CAL-27 cell was assayed by flow cytometry. Results Compared with the control group, FRMD4A mRNA expression significantly reduced in FRMD4A-siRNA interfering group (94%) and the cell proliferation index decreased(P<0.05). The cell cycle arrested in G1 period (P<0.05). Conclusion FRMD4A-siRNA could effectively inhibit FRMD4A mRNA expression in tongue cancer CAL-27cell, impact the distribution of cell cycle, and reduce cell proliferation.

Objective To observe the application effect of a quantitative nursing management program in the operating room constructed based on risk assessment strategies for patients with osteo-chondroma.Methods Thirty patients who underwent osteochondroma surgery from July 2021 to June 2022 at Suqian Hospital Affiliated to Xuzhou Medical University were set as control group(receiving conventional nursing management),and 30 patients who underwent osteochondroma surgery from July 2022 to June 2023 were set as study group(receiving quantitative nursing management centered on risk assessment strategies).The perioperative indicators,psychological stress status,self-care abili-ty,quality of life,and complication occurrence were compared between the two groups.Results The recovery time of gastrointestinal function,postoperative anal exhaust time,and hospital stay in the study group were(0.72±0.12),(1.71±0.32),and(21.32±3.47)days,respectively,which were shorter than(1.04±0.28),(2.02±0.42),and(28.02±4.02)days in the control group(P＜0.05).After nursing,the scores of the Self-rating Depression Scale and Self-rating Anxiety Scale in the study group were(36.87±5.64)and(32.42±6.82),respectively,which were lower than those(45.24±6.32)and(48.33±6.56)in the control group(P＜0.05).After nursing,the total scores of the Exercise of Self-Care Agency Scale(ESCA)and SF-36 Scale in the study group were(142.87±15.62)and(86.42±7.28),respectively,which were higher than(125.42±16.32)and(78.33±8.56)in the control group(P＜0.05).The total complication rate in the study group was 6.67％,which was lower than 26.67％in the control group(P＜0.05).Conclusion The quantitative nursing management program in the operating room constructed centered on risk assess-ment strategies can effectively improve the postoperative recovery effect of patients with osteochon-droma,relieve psychological stress responses,enhance self-care ability and quality of life,and re-duce the occurrence of complications.

Objective To observe the application effect of a quantitative nursing management program in the operating room constructed based on risk assessment strategies for patients with osteo-chondroma.Methods Thirty patients who underwent osteochondroma surgery from July 2021 to June 2022 at Suqian Hospital Affiliated to Xuzhou Medical University were set as control group(receiving conventional nursing management),and 30 patients who underwent osteochondroma surgery from July 2022 to June 2023 were set as study group(receiving quantitative nursing management centered on risk assessment strategies).The perioperative indicators,psychological stress status,self-care abili-ty,quality of life,and complication occurrence were compared between the two groups.Results The recovery time of gastrointestinal function,postoperative anal exhaust time,and hospital stay in the study group were(0.72±0.12),(1.71±0.32),and(21.32±3.47)days,respectively,which were shorter than(1.04±0.28),(2.02±0.42),and(28.02±4.02)days in the control group(P＜0.05).After nursing,the scores of the Self-rating Depression Scale and Self-rating Anxiety Scale in the study group were(36.87±5.64)and(32.42±6.82),respectively,which were lower than those(45.24±6.32)and(48.33±6.56)in the control group(P＜0.05).After nursing,the total scores of the Exercise of Self-Care Agency Scale(ESCA)and SF-36 Scale in the study group were(142.87±15.62)and(86.42±7.28),respectively,which were higher than(125.42±16.32)and(78.33±8.56)in the control group(P＜0.05).The total complication rate in the study group was 6.67％,which was lower than 26.67％in the control group(P＜0.05).Conclusion The quantitative nursing management program in the operating room constructed centered on risk assess-ment strategies can effectively improve the postoperative recovery effect of patients with osteochon-droma,relieve psychological stress responses,enhance self-care ability and quality of life,and re-duce the occurrence of complications.

Objective: To explore the diagnosis, treatment and prognosis of synovial chondroma in the temporomandibular joint and to provide a reference for clinical diagnosis and treatment. Methods : A case of right temporomandibular joint synovial chondromatosis admitted to the Stomatological Hospital, Southern Medical University was reported, and the related literature was reviewed and analyzed. Results : During the movement of the mandibular opening, noise and obvious pain were found. The imaging features showed that several free calcification shadows of different sizes were seen around the condyle in the right articular fossa. The right temporomandibular joint mass resection and articular disc reduction were performed under general anesthesia, and the postoperative pathological results showed synovial chondromatosis. The patient′s symptoms were relieved 3 months after the surgery, and the imaging examination showed no residual lesions. A review of the literature shows that synovial chondromatosis usually occurs in large joints, such as the knee, hip, elbow, and shoulder joints, and rarely occurs in the temporomandibular joint. It occurs in middle-aged patients, manifesting as pain, swelling, and limited movement. Imaging studies play an important role in diagnosis, but the final diagnosis requires pathological diagnosis. Surgical treatment is effective, and synovial chondromatosis does not easily relapse. Conclusion The diagnosis of TMJ synovial chondroma should be combined with clinical manifestations, imaging features, and pathological examination. Surgery is an effective treatment. After completely removing the diseased and affected tissues, the disease has a good prognosis and does not easily relapse.