Objective: To observe and analyze clinical characteristics of patients with coronary myocardial bridge (CMB) and explore its therapeutic methods. Methods: To retrospectively analyze clinical data of 340 patients undergoing selective coronary angiography (CAG) in our hospital from Jan 2011 to Jan 2013. Results: A total of 33 CMB cases (9.7%) were found in 340 patients undergoing CAG, including 29 cases（87.9%）with isolated myocardial bridge and four patients with coronary atherosclerosis-like changes. There were 31 cases (93.9%) located in left anterior descending branch (LAD), one case (3.03%) in the first diagonal branch (D1) and one case (3.03%) in left circumflex artery (LCX). According to Noble classification of stenosis, 19 cases (57.6%) were class 1, 12 cases (36.4%) were class 2 and two cases (6.06%) were class 3. A total of 16 cases (48.5%) had typical symptoms of angina pectoris, 15 cases (45.5%) had chest tightness and two cases (6.06%) had palpitations. In electrocardiogram and/or dynamic electrocardiogram, ST-T or T wave changes were found in 19 cases (57.6%). All patients received β-receptor blocker and/or non-dyhydropyridine calcium channel blocker, and 29 patients (87.7%) with symptoms improved. Conclusion: Clinical symptoms and manifestations of myocardial bridge is diverse, β-receptor blocker and non-dyhydropyridine calcium channel blocker can relieve most clinical symptoms caused by myocardial bridge.