[Objective] To explore academic value of Shanghanfenjing. [Methods] In this paper, the comprehensive study on the subject that Wu Yiluo 's lifetime in the Qing Dynasty, in his book, evaluating and analyzing the relevance between Shanghanfenjing and Yu Jiayan's Shanglunpian, evaluate the academic value of theShanghanfenjing. [Results]Shanghanfenjinginherits Yu Jiayan'sShanglunpianacademic ideas, explains in detail the Shanghan-lunprovisions in the exogenous Febrile Diseases, is a popular textbook version of theory on febrile disease. [Conclusion]Shanghanfenjinghas more im-portant research value of theory on exogenous febrile disease,is easy to understand the popularity of reading of exogenous febrile disease ,Wu Yiluo is one of the distinguished medical scientists in the Qing Dynasty.