Objective To explore the moderating or mediating effects of life-meaning between optimism and suicide risk in undergraduates.Methods A total of 1310 college students from one Chinese university completed a survey that included Suicidal Behaviors Questionnaire-Revised (SBQ-R),the Life Orientation Test-Revised (LOT-R) and the Chinese meaning in life questionnaire (C-MLQ).Results The total scores of SBQ-R,LOT-R and C-MLQ of undergraduate were (5.04 ± 2.28),(11.22 ± 2.07) and (37.22 ± 5.22),respectively.Optimism had significant negative correlation with suicide risk (r =-0.22,P ＜ 0.01),and positive correlation with life-meaning (r=0.28,P＜0.01).Life-meaning had significant negative correlation with suicide risk (r=-0.18,P＜0.01).The life-meaning's moderating effects between optimism and suicide risk were not significant(P ＞ 0.05),while the relationship between optimism and suicide risk was mediated by life-meaning,and the mediating effect was 0.07,which accounted for 17％ of the total effects.Conclusion Life-meaning doesnt morderating effect,but partially mediates the relationship between optimism and suicide risk.

Objective To study the MR imaging characteristics of benign cerebellar astrocytomas(BCAs) in children. Methods The clinical and MR imaging data of twelve patients with BCAs were reviewed and analyzed retrospectively.Results Of 12 tumors, 7 cases were located in the cerebellar hemisphere, 4 in the vermis, and 1 in the IV ventricle. All children were in company with hydrocephalus rated as extensive (n=9) or moderate (n=3). The tumors ranged in diameter from 23 mm to 68 mm, mean diameter 42 mm. Solid tumors were found in 5 children, and cystic areas occurred in 7 of 12 patients.BCAs were hypointense on T 1-weighted in 10 cases, and hyperintense on T 2WI in 9 cases compared with that of normal brain parenchyma. After contrast injection, BCAs marked (n=2), moderate (n=5), or absent (n=5) enhancement. Hemorrhage and calcification were not common (n=1,0, respectively).Conclusion BCAs has relative characteristic features on MRI in children, and MRI plays an important role in diagnosing and evaluating these tumors preoperatively.

OBJECTIVETo explore the incidence of suicide exposure and its association with suicide risk in Chinese college students, and study the modulatory effects of suicide exposure on the relations between life events and suicide risks.

METHODSA total of 8202 college students from 12 Chinese colleges and universities in mainland China completed a cross-sectional survey that included suicidal behaviors questionnaire-revised (SBQ-R), Adolescent Self-Rating Life Events Check List (ASLEC), suicide exposure questionnaire, social and demographic characteristics questionnaire.

RESULTSThe incidence of exposure to suicide events involving close relatives and acquaintances were 3.9% and 11.8% among sampled Chinese college students, respectively. Students exposed to suicide events involving close relatives had significantly higher total SBQ-R scores than those who did not (5.51∓2.44 vs 4.68∓2.11, P<0.01), and suicide events of acquaintances were also associated with significantly increased total SBQ-R scores (5.51∓2.44 vs 4.68∓2.11, P<0.01); these suicides events all contributed to significantly increased rates of suicidal ideation, suicide plans and suicide attempts in the college students (P<0.05). The life events showed a significant positive correlation with suicide risks (0.11≤r≤0.26, P<0.01). The interactions of exposure to suicide events involving close relatives and acquaintances and the interactions of life events and suicide of close relatives for suicide risk were not significant (P>0.05), but exposure to acquaintance suicide events moderated the effects of life events on suicide risk (P<0.01), and the college students with a high level of life events and history of acquaintance suicide had the highest risk for suicide.

CONCLUSIONIn Chinese college students, the risk of suicide is closely associated with exposure to suicide events and life events, and exposure to suicide events involving acquaintances can modulate the effects of life events on suicide risk.

Adolescent ; Adult ; Asian Continental Ancestry Group ; Cross-Sectional Studies ; Female ; Humans ; Life Change Events ; Male ; Risk Factors ; Students ; Suicidal Ideation ; Suicide ; statistics & numerical data ; Surveys and Questionnaires ; Young Adult

Objectives:To design a self-control training program based on the recent findings of self-control and self-regulation after taking full consideration of the unique characteristics of depression disorder,with an emphasis on behavioral activation and reinforcement.Methods:Totally 46 students who were diagnosed with major depression were randomly assigned to one of the two groups:Group 1 (n =23),and Group 2 (n =23).Participants in the Group 1 received 24-week self-control training program,as compared to Group 2 who received only baseline and post-24-week-intervention measurements,the measurements included Self-control Scale (SCS) and Beck Depression Inventory (BDI-Ⅱ).The self-control training included eight-week training modules and 16-week consolidation module.Results:In Group 1,the SCS scores were higher in post-intervention than in baseline measurement [(38.0 ± 6.3) vs.(34.7 ± 8.2),P ＜ 0.01],and the BDI-Ⅱ scores were lower in post-intervention than in baseline measurement [(19.0 ± 6.1) vs.(21.8 ± 4.8),P＜0.01] in Group 1.Whereas in Group 2,there were no significant differences between baseline and post-24-week-intervention measurements of SCS and BDI-Ⅱ scores (Ps ＞0.05).Conclusion:The study provides new evidence for the self-regulation model of depression.Self-control training could be an effective intervention strategy for the treatment of depression.

Objective To explore the role of mindfullness in the negative life events,depression,and poor sleep quality.Methods Using five facet mindfullness questionnaire(FFMQ),adolescents self-rating life events checklist (ASLEC),self-rating depression scale (SDS) and Pittsburgh sleep quality index (PSQI) to investigate 2 792 freshmen in a medical university in Guangzhou.Results The FFMQ score (126.02±12.14) was negatively correlated with ASLEC score(23.93±19.81),SDS score(35.89±7.31) and PSQI score (3.45±2.13) (r=-0.17,r=-0.44,r=-0.26,P＜0.01).The boys in the aspects of " mindfullnessinaction" scored significantly higher than that of girls (21.20 ± 3.36,20.52±2.88,P＜0.01).The girls scored significantly higher than boys in the PSQI,SDS (3.58±2.15,3.21 ±2.08,P＜0.05;36.22±7.26,35.27±7.35,P＜0.01).Mindfullness and sleep quality showed a chain-mediated effect between negative life events and depression,and the model fitting was good (RMSEA =0.048,CFI =0.962,TLI =0.943).The total mediating effect size was 61.41％.The mediating path through mindfullness,with the effect size of 16.71％,and the chain-mediating effect was 8.94％.Conclusion The higher the level of mindfullness,the lower the individual's depression score and the better the quality of sleep.Mindfullness and the sleep quality play a role of chain-mediating effect between negative life events and depression.

Autologous ozonized blood transfusion(AOBT) is a therapy of re-transfusion of 100-200 mL of autologous blood after shaking and agitation with appropriate amount of oxygen-ozone in vitro. The oxidation of blood through the strong oxidation of ozone can enhance the non-specific immune response of the body, regulate the internal environment and promote health. This therapy has been increasingly applied in clinical practice, while no unified standard for the operation process in terms of ozone concentration, treatment frequency and treatment course had been established. This operation process of AOBT is primarily explored in order to standardize the operation process and ensure its safety and efficacy.