The invasion and metastasis of tumor as the primary cause of death in cancer increases not only the patient's suffering, but also the difficulty of clinical treatment. It is an important guiding to find the molecular biological tumor markers and gene targets of antirecurrence and antimetastasis for clinical treatment. The invasion and metastasis of tumor is a complex process including the biological characteristics of the cancer, interaction among host cells, extracellular matrix and cancer cells, etc. Recently, epithelial mesenchymal transition (EMT) is becoming a hot spot in oncology research by virtue of its effect on genesis and development of tumor. Currently, the known markers of EMT include epithelial marker proteins mainly containing E-cadherin and interstitial marker proteins mainly containing N-cadherin and vimentin. It is necessary to make a summary among the studies on three proteins.

Objective To analyze the contemporary TCM academic team of lung cancer, summarizes its main academic thoughts. Methods To represent characters, important documents, and the main academic ideas as the basis of a team. From the perspective of the literature, literature of Chinese medicine against lung cancer, adopt the method of literature metrology, and social network analysis the candidate teams were found;the method of literature investigation evaluation candidate team heritage was adopted, the main academic thoughts from each team representative was summarized. Results A total of 8 441 researchers published 5 030 papers about treatment of lung cancer with TCM. 91 researchers with large amount papers and seven academic team were found. Conclusion Chinese medicine treatment of lung cancer made a great progress in the contemporary, team enriched the TCM system of principle, method, square, medicine.

Objective To explore the contemporary academic teams engaged in research on knee osteoar-thritis(KOA),so as to summarize their main members and primary academicideas.Methods From the Chinese biomedical literature database (CBM)from 1900 to 2015,the TCMliterature linked to KOA was searched out,from which the author information was extracted using regular expressions,prolific au-thors were screened out using Price Law,academic teams were found using UCInet software.Then,im-portant academic teams screened out according to H index were visualized using Netdraw software to find out their main members from whom the chief members’academic ideas on KOA were explored and sum-marized.Results Atotal of 7 375 authors with 3932 TCM paperson KOA wereincluded,86prolific authors belonging to nine academic teams,and five teams were important—LIU Xianxiang Team,ZHAO WenhaiTeam,LIUDeyuTeam,WEN Jianmin Team and FANYueguangTeam.Conclusion Thecon-temporary TCM academic teams which have special features on treatment KOA,inherit and carry forward the TCM theories from different views in clinical research and practice.