1.Effect of Chinese herbs on muscle protein metabolism in nephrotic rats
Menghua CHEN ; Liying LI ; Jisheng PAN
Chinese Journal of Nephrology 1997;0(03):-
To investigate the effect of Chinese herbs (Astragalus-As,Angelica-An,AG-a composition of Astragalus) on muscle protein metabolism in nephrotic rats. Methods The method of incorporation of [3 H-phenylalanine ] ([3 H-phe]) into the muscle was used. Results (l)The incorporation of [3 H-phe] into the muscle of untreated nephrotic rats (1.12 ? 0.37) was significantly lower than ihe normal control rats (2.25?0.47) ( P
2.Application of Anatomical Liver Resection in Treatment of Bilateral Hepatolithiasis
Yishuang PAN ; Yongyi OU ; Xiangguo LI ; Quanbo ZHOU ; Jisheng CHEN
Journal of Kunming Medical University 2013;(12):90-95
Objective To explore the value of anatomical liver resection in the treatment of bilateral intrahepatic biliary lithiasis. Methods We collected the clinical data of 32 patients with bilateral intrahepatic biliary lithiasis who received anatomical liver resection and 25 patients who recevied non-anatomical liver resection from May 2010 to May 2012 in our hospital and Sun Yat-sen Memorial Hospital. We comapred the therapeutic efficacy of these two operative modalities in the diagnosis and treatment of bilateral intrahepatic biliary lithiasis. Results The intraoperative blood loss was 436 ±48.162 mL in patients who received anatomical liver resection, and was significantly less than that in the control group (763 ± 37.645ml) ( < 0.05 ) . Postoperative liver function status:for patients who received anatomical liver resection,on the third day after operation,the total bilirubin and AST were significantly lower than those in the control group ( <0.05), and the postoperative hospitalization time was also shorter than that of the control group ( <0.05 ) . The two groups in the operation time, postoperative complications and residual calculus had no significant difference ( >0.05 ), but there 1 patients died of liver failure in the control group. Conclusions Anatomical liver resection is a favorable method to completely remove the lesions under the premise of retaining the residual liver function as much as possible. The rate of remnant biliary lithiasis and recurrence is lower and the recovery is quicker in these patients after anatomical liver resection. Thus, anatomical liver resection is worthy of promotion.
3.Function on Stable Angina Pectoris Patients on Electroacupuncture Heart Sutra and Pericardial Sutra Point
Jiang PAN ; Jisheng LIU ; Zhi LIU ; Wenying SHI ; Li LI ; Wei ZHANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(9):1564-1570
Objective: to compare the immediate effects of electroacupuncture (EA) on electrocardiogram and cardiac function in patients with stable angina pectoris by comparing the anti-myocardial ischemia effects of the EA and pericardial meridians (PC) with heart, the heart meridians (HS) and heart. To explore the correlations and differences between cardio, pericardial and cardiac, and to provide some clinical basis for the clinical treatment of this disease.Methods: 45 patients who met the criteria were divided into three groups by single blind randomized reference method:15 cases of pericardial therapy group, 15 cases of pericardial therapy group, and 15 cases of non-acupoint control group.The heart group, according to the meridians following the direction of acupuncture polar spring, Shaohai, Lingdao, Shimen; Heart bag group, according to the direction of the meridians needle Tianquan, Quze, Neiguan, Daling; Non-nonpoint group acupuncture is not non-point F1, F2, F3, F4. Compare the changes in heart rate and the value of the heart rate and the value of the heart rate of the 15 min electrocardiogram, and the value of the body Doppler Tei in the group before and immediately after the acupuncture and the end of the acupuncture. Results: Compared with the preacupuncture, there was no significant change in the cardiac and pericardial groups in the 15 minutes immediately after the acupuncture and the end of the acupuncture (P> 0.05), and the heart rate was significantly slower (P> 0.05) . The value of was significantly increased (P < 0.05), and the tissue Doppler Tei index was significantly reduced (P < 0.05) .There was no significant change before and after the non-point group indicators (P> 0.05) . Compared with the pericardial group, the two groups had the same effect on electrocardiogram and cardiac function (P> 0.05) . Compared with the immediate after the end of acupuncture, the 15 min, cardio group and pericardial group after the end of acupuncture slowed the heart rate, increased the T value and reduced the tissue Doppler Tei index (P < 0.05) .Conclusion: Electroacupuncture and pericardial points can specifically slow the heart rate of patients with stable angina pectoris, restore the changes of T wave ischemia, and reduce the tissue Doppler Tei index, indicating that acupuncture of both acupuncture points has an immediate effect against myocardial ischemia. The effects of electroacupuncture and pericardial meridians on heart rate and T and tissue Doppler Tei indices are quite similar, suggesting that the immediate effects of acupuncture and pericardial meridians against myocardial ischemic injury are comparable. Electroacupuncture heart meridians and pericardial meridians have a certain post-acupuncture effect.
4.Diagnostic model for intelligent recognition of thyroid function by thyroid imaging based on deep neural network
Tingting QIAO ; Zhijun CUI ; Haidong CAI ; Ming SUN ; Wen JIANG ; Yingchun SONG ; Xiaqing YU ; Junyu TONG ; Shuhan PAN ; Jisheng ZHAO ; Zhongwei LYU ; Dan LI
Chinese Journal of Nuclear Medicine and Molecular Imaging 2019;39(7):403-407
Objective To develop a diagnostic model based on deep neural network for intelligent discrimination of thyroid function. Methods A total of 1616 patients ( 283 males, 1333 females, average age:52 years) who underwent thyroid imaging between May 2016 and June 2018 were selected. According to the clinical diagnosis, the 1616 cases included 299 normal thyroid cases, 876 hyperthyroidism cases and 441 hypothyroidism cases. Feature extraction and learning training were performed on 1000 training set sam-ples by two deep neural network models ( AlexNet;deep convolution generative adversarial networks ( DCGAN) ) using deep learning algorithm. Performance verifications were implemented on 616 test set samples. The con-sistency between the verification results of the two models and the clinical diagnosis was analyzed by Kappa test. Meanwhile, the time advantage of the intelligent diagnosis models was analyzed. Results The average diagnostic time of AlexNet model was 1 s/case, and the classification accuracy for normal thyroid, hyperthy-roidism, hypothyroidism were 82.29%(79/96), 94.62%(369/390), 100%(130/130), respectively. The Kappa value between results of AlexNet model and clinical diagnosis was 0.886 ( P<0.05) . The average di-agnostic time of DCGAN model was 1 s/case, and the classification accuracy for normal thyroid, hyperthy-roidism, hypothyroidism were 85.42%(82/96), 95.64%(373/390), 99.23%(129/130), respectively. The Kappa value between results of DCGAN model and clinical diagnosis was 0.904 ( P<0.05) . Conclusion The deep neural network intelligent diagnosis model can quickly determine the functional status of thyroid gland in thyroid imaging, and it has a high recognition accuracy, thus providing a new method for thyroid image review.