Objective To develop the Chinese version of Patient Learning Needs Scale(PLNS), and evaluate the feasibility, validity and reliability of the developed scale. Methods The standard procedure of cross-culture adaptation was used to develop the Chinese version PLNS. A total of 385 adults hospitalized with a medical or surgical illness completed the Chinese version PLNS. The feasibil-ity and psychometric properties of the scale such as, internal consistency, split-half reliability, content validity and construct validity were evaluated. Results Questionnaire recovery rate of the investiga-tion was 98.5%,the completion rate was 97.7%. Average time of completing was (13.75±4.36) min. The overall Cronbaeh's α coefficient was 0.95 and the value of a in 5 subscales of PLNS ranged from 0.75 to 0.86. The overall split-half reliability coefficient was 0.95 and the value of split-half in 5 subscales of PLNS ranged from 0.802 to 0.876. The CVI for content validity was 0.86. The construct validity was con-finned by factor analysis with 55,08% variance was explained by 9 factors. Conclusions An accept-able psychometric property of the Chinese version of PLNS was indicated. PLNS could be used as positive aspects measurement of general patients'perceptions of learning needs while discharging.It might be help-ful for care and further clinical study.

Objective To study the teaching effects of using case discussing-analysis method in the teaching course of Nursing Research among nursing students,and then make suggestion for relative teaching improvement. Methods Nursing students of Grade 2003 in main school and Grade 2004 in the affiliated WUZHOU school were divided into the trial group and control group at random. Part of teaching contents of nursing research were taught to the trial group students by case discussing-analysis method,and to the control group students by the methods of lecture-based learning. The teaching effect was evaluated after the course end. Results The ability of design to scientific research,recognition of Nursing research,learning attitude and learning interest,etc,in the trial group students were obviosly better than those in the control group students,and there was significant by statistical test. Conclusions Case discussing-analysis method can effectively excite the interest and the potential of students,and improve the ability of discovering and solving problems.

Objective To introduce the current value of multi-detector row CT (MDCT) and magnetic resonance imaging (MRI) techniques on evaluation of diffuse hepatic parenchymal diseases. Methods By literature review,the application and recent advances of various kinds of MDCT and MR imaging techniques in evaluating diffuse hepatic parenchymal diseases were summarized. Results There were three kinds of diffuse liver parenchyma diseases,which were the diseases of storage,vascular and inflammatory. The morphology changes of diffuse liver parenchyma diseases could be demonstrated well by MDCT. MRI,especially MR functional imaging could reflect the morphology changes,and cellular metabolic activity of the liver,which provided qualitative and quantitative information for the diagnosis and evaluation of therapeutic effect on diffuse liver parenchyma diseases. Conclusion MR imaging techniques,especially those functional techniques,developed rapidly and had practical value in both the diagnosis and severity assessment of hepatic fibrosis.

Objective To summarize the principle and application of functional MR imaging of pancreatic carcinoma and chronic mass-forming type pancreatitis.Methods Articles about diffusion-weighted imaging(DWI),magnetic resonance spectrum imaging(MRSI) and dynamic contrast-enhanced MR imaging of pancreatic carcinoma and chronic pancreatitis were reviewed and analyzed.Results Functional MR imaging could reflected the differences in molecules diffusion,metabolism and tissue perfusion between pancreatic carcinoma and chronic pancreatitis.Conclusion As a non-invasive protocol,functional MR imaging can provide useful information in differential diagnosis between chronic mass-forming type pancreatitis and pancreatic carcinoma.

Objective To investigate the value of MR diffusion-weighted imaging (DWI) in differentiating pancreatic carcinoma from chronic focal pancreatitis on 3.0 T MR system. Methods Thirteen patients with proved pancreatic carcinoma, 7 patients with confirmed chronic focal pancreatitis, and 14 healthy volunteers, were included in this study. MR examination including the routine abdomen scanning protocol and DWI was performed for both patients and volunteers. The SE-EPI sequence and ASSET technique were used for DWI. The b values of 400, 600, 800 and 1 000 s/mm2 were selected to acquire the DWI. The corresponding apparent diffusion coefficient (ADC) values were measured in each designated region of interest and statistically analyzed. Results ①DWI of the healthy volunteers showed intermediate signals of pancreas. ②DWI of pancreatic tumor masses showed homogenous high signal intensity relative to the surrounding pancreatic tissue with clear boundary. Under different b values, the tumor ADC values were (1.63?0.235)?10-3 mm2/s, (1.42?0.126)?10-3 mm2/s, (1.36?0.170)?10-3 mm2/s and (1.26?0.178)?10-3 mm2/s respectively, which were significantly lower than those of non-tumor region (2.11?0.444)?10-3 mm2/s, (1.83?0.230)?10-3 mm2/s, (1.81?0.426)?10-3 mm2/s, (1.60?0.230)?10-3 mm2/s and of the normal pancreas (1.85?0.350)?10-3 mm2/s, (1.69?0.290)?10-3 mm2/s, (1.67?0.268)?10-3 mm2/s, (1.42?0.221)?10-3 mm2/s, P

Objective To understand the needs of health education of TCM health preservation and re-habilitation in community patients with chronic disease in order to instruct nurses to carry out health education pur-posively. Methods A questionnaire survey was carried out in 320 patients with coronary heart disease, hyper-tension, chronic liver disease, diabetes mellitus, chronic obstructive pulmonary disease(COPD) and other chronic diseases. The investigation contents included cognition of TCM health preservation and rehabilitation, knowledge needs and demand patterns and the results underwent analysis. Results In 320 patients, 11% of patients understood the TCM health preservation and rehabilitation-related knowledge, 43% understood part of it, 46% knew nothing about it. All patients showed different degree of needs for TCM .health preservatiou and reha-bilitatiou and different demand patterns,and the total demand for various educational content was above 90%. Needs for disease prevention, health seasons, TCM dietetic therapy occupied the first three. Health care workers o-ne- to-one education was the most popular form of health education. 75% of the patients hoped that the family members were given health education at the same free. Conclusions Patients with chronic disease possess de-ficient but greater needs for knowledge about TCM health preservation and rehabilitalion. The awareness and ca-pability of serf-care, health preservation and rehabilitation and prevention-tirst should be improved.

Objective To determine the clinical characteristic, main treatment, and prognosis for the sake of more effective treatments for critically ill patients with H1N1 influenza. Methods Eight critically ill patients with H1N1 influenza in intensive care unit were retrospectively studied, including clinical characteristics, indexex of correlation, and prognosis. Results The acute physiology and chronic health evaluationⅡ score was 19.0±7.8. Five patients died, 4 of whom were caused by respiratory failure. The number of platelets in dead patient was lower than that in healing and improved ones(χ2=8.000,P＜0.05).All the 4 patients treated with glucocorticoid died, 5 out of the 6 patients received invasive mechanical ventilation rather than noninvasive mechanical ventilation, and 3 of them who complicated barotraumas in the lung died at last. Conclusion Critically ill patients with H1N1 influenza have high mortality. Respiratory failure is the main cause of death. Critically ill patients with H1N1 influenza should not be treated with glucocorticoid. Patients who need mechanical ventilation should be treated with invasive mechanical ventilation with low tidal volume and low positive end-expiratory pressure.

Objective To establish a system of the screening, evaluation and intervention of congenital heart disease (CHD) in China. Methods All infants (16070) born in Changzhou Maternal and Child Health Hospital from May 1st 2011 to April 30th 2013 were screened for CHD. The infants with CHD were followed up till 1 year of age. Results One hundred and three infants were diagnosed with CHD, and the incidence rate was 0.641%. The top three CHD types in incidences were VSD (0.205%), PDA (0.174%) and ASD (0.10%), respectively. In these infants, 94 cases were followed-up and 9 cases were lost. The incidence of small gapped VSD, ASD and premature PDA were high. Some infants with serious CHD were subjected to surgery, and others were still followed up. Conclusions The incidence of CHD in Changzhou is comparable with that in the whole country. The follow-up can improve the life quality of CHD infants.

Objective To investigate the effect of pyrrolidine dithiocarbamate(PDTC)on Pseudomonas aeruginosa induced pneumoneia of rats.Metheds A PA induced pneumonia model was established in Sprague-Dawley(SD)rats.Sixty minutes before PA exposure,PDTC and normal saline were injected into abdominal cavity separately.At 3,9,and 24 h after PA exposure,the rats were sacrificed,and the wet/dry ratio(W/D)of lung tissue was measured and histopathologic changes were observed.The number of in-filtrated polymorphonuclear(PMN)leukocytes was calculated.Immunohistochemical staining with activated NF-?B antibody was performed to detect the expression of NF-?B in lung tissues.The changes of IL-8 levels in bronchoalveolar lavage were identified by ELISA.Results Histology findings demonstrated that PA exposure induced obvious changes in lung structure,and edema and pronounced inflammatory cells infiltration were observed.Both symptoms and lesions of lung were lesser in the rats of PDTC group than those of the PA group.Compared with PDTC group,the activation of NF-?B and the expression of IL-8 were significantly up-regulated after PA challenge 3~24 h(P

Objective:To observe the effect of Radix Paeoniae Bubra(RPB)on NADPH oxidase p22phox,monocyte chemotactic protein-1(MCP-1)mRNA expression and neointimal hyperplasia after carotid artery balloon injury in cholesterol-fed rabbits.Methods:The rabbit model of carotid balloon injury was established adopting Clowes method,and treated with extract of RPB.Component of neointima and expression of proliferating cell nuclear antigen(PCNA)and macrophage was determined by immunochemical stain.The collagen of typeⅠwas detected by special staining for blood vessels and the area of neointima was measured by image assay system.Expression of NADPH oxidase p22phox mRNA,MCP-1 mRNA was detected by in situ hybridization and transcription-polymerase chain reaction.Results:RPB can attenuate the neointima area and proliferation of collagen typeⅠinduced by balloon-injury,remarkable prevent the formation of restenosi,and down-regulate expression of NADPH oxidase p22 and MCP-1mRNA significantly and decrease the degree of macrophages infiltration especially in vessel wall of injuring carotid artery.Conclusions:RPB inhibited NADPH oxidase P22Phox and MCP-1 mRNA expression,and modestly reduced neointimal hyperplasia,which might be partly attributed to its antioxidant and inflammatory effects.