1.Research and Practice on the Teaching Model of Physiology for Students of College Training to Achieve University Degree in the PLA
Peisen PAN ; Jinxia GENG ; Dawei ZHENG
Chinese Journal of Medical Education Research 2003;0(02):-
A questionnaire was taken in regard to the basic situation and study requirement for students of college training who want to get a university degree in the PLA.Some practical improvement was made and a preliminary model of physiological teaching for such students was established
2.Effects of Electroacupuncture plus Oxygenmedicine on the Expression of Bcl-2 and Bax Proteins in the Hippocampal CA 1 Area in Rats with Global Cerebral Ischemia/Reperfusion Injury
Yuan BU ; Peiying ZHANG ; Deqin GENG ; Jinxia CAO ; Jizhen LI
Acupuncture Research 2010;0(03):-
Objective To observe the effect of electroacupuncture (EA) plus oxygenmedicine (OM) on the expression of Bcl-2 and Bax in the hippocampal CA 1 area in cerebral ischemia/reperfusion injury (CI/RI) rats. Methods Thirty SD rats were randomized into sham-operation,model,EA,OM,EA+OM groups (n=6/group). CI/RI model was established by using modified Pulsinelli 4 vessel occlusion and reperfusion. EA (100 Hz,3.5 mA) was applied to "Baihui" (GV 20) and "Zusanli" (ST 36) 30 min,once daily for 4 days. Rats of OM and EA+OM groups were put into a box filled with oxygen and atomized herbal medicines containing Bingpian (Borneolum),Shexiang (Moschus),Huangjing (Rhizoma Polygonati),Shouwu (Radix Polygoni Multiflori),etc. for 30 min,once daily for 4 days. Bcl-2 and Bax expression of the hippocampal CA 1 area was detected by immunohistochemistry. Results Compared with sham group,the numbers of Bcl-2 immunoreaction (IR) and Bax IR positive cells,and the immunoactivity of Bcl-2 IR and Bax IR positive products in the hippocampal CA 1 area were increased significantly in model group (P0.05). Conclusion EA and OM and EA+OM can effectively regulate the expression of Bcl-2 and Bax in the hippocampal CA 1 area in CI/RI rats,and the effects of EA+OM are significantly superior to those of simple EA and simple OM,which may contribute to their effect in improving cerebral ischemia.
3.Effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease and hypertension
Jinxia WANG ; Juxin WANG ; Jing LIU ; Chang GENG
Journal of Clinical Medicine in Practice 2023;27(23):43-46,53
Objective To explore the effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease complicated with hy-pertension.Methods A total of 120 patients with coronary heart disease combined with hypertension were selected as study objects,and were divided into two groups according to treatment methods,with 60 patients in each group.The conventional group was treated with amlodipine tablets combined with atorvastatin calcium tablets,and the Anshen prescription group was treated with Yiqi Tongluo Anshen Recipe on the basis of the conventional group.The levels of Salusin-β,lipoprotein-associated phospho-lipase A2(LP-PLA2),high-sensitivity C-reactive protein(hs-CRP),pentamylin 3(PTX3),tumor necrosis factor-α(TNF-α)and blood pressure of the two groups were recorded before and after treat-ment,and the TIMI3 rate of coronary blood flow in myocardial infarction thrombolysis test(TIMI)and the adverse reaction rate during treatment were analyzed.Results The total effective rate of TCM syn-drome in the Anshen prescription group was higher than that in conventional group(P<0.05).After treatment,systolic blood pressure(SBP)and diastolic blood pressure(DBP)in two groups were lower than before treatment,and SBP and DBP in the Anshen prescription group were lower than those in the conventional group(P<0.05).The rate of coronary blood flow TIMI3 in the Anshen prescrip-tion group was higher than that in the conventional group(P<0.05).After treatment,levels of Sa-lusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α in two groups were decreased compared with those before treatment,and levels of Salusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α levels of in the Anshen prescription group after treatment were lower than those in the conventional group(P<0.05).There was no significant difference in the incidence of adverse reactions between the Anshen prescription group and the conventional group(P>0.05).Conclusion Yiqi Tongluo Anshen Recipe combined with statins in the treatment of coronary heart disease with hypertension can reduce the expression of related factors,improve coronary blood flow and the curative effect.
4.Effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease and hypertension
Jinxia WANG ; Juxin WANG ; Jing LIU ; Chang GENG
Journal of Clinical Medicine in Practice 2023;27(23):43-46,53
Objective To explore the effect of Yiqi Tongluo Anshen Recipe combined with statins on coronary blood flow and blood pressure in patients with coronary heart disease complicated with hy-pertension.Methods A total of 120 patients with coronary heart disease combined with hypertension were selected as study objects,and were divided into two groups according to treatment methods,with 60 patients in each group.The conventional group was treated with amlodipine tablets combined with atorvastatin calcium tablets,and the Anshen prescription group was treated with Yiqi Tongluo Anshen Recipe on the basis of the conventional group.The levels of Salusin-β,lipoprotein-associated phospho-lipase A2(LP-PLA2),high-sensitivity C-reactive protein(hs-CRP),pentamylin 3(PTX3),tumor necrosis factor-α(TNF-α)and blood pressure of the two groups were recorded before and after treat-ment,and the TIMI3 rate of coronary blood flow in myocardial infarction thrombolysis test(TIMI)and the adverse reaction rate during treatment were analyzed.Results The total effective rate of TCM syn-drome in the Anshen prescription group was higher than that in conventional group(P<0.05).After treatment,systolic blood pressure(SBP)and diastolic blood pressure(DBP)in two groups were lower than before treatment,and SBP and DBP in the Anshen prescription group were lower than those in the conventional group(P<0.05).The rate of coronary blood flow TIMI3 in the Anshen prescrip-tion group was higher than that in the conventional group(P<0.05).After treatment,levels of Sa-lusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α in two groups were decreased compared with those before treatment,and levels of Salusin-β,LP-PLA2,PTX3,hs-CRP and TNF-α levels of in the Anshen prescription group after treatment were lower than those in the conventional group(P<0.05).There was no significant difference in the incidence of adverse reactions between the Anshen prescription group and the conventional group(P>0.05).Conclusion Yiqi Tongluo Anshen Recipe combined with statins in the treatment of coronary heart disease with hypertension can reduce the expression of related factors,improve coronary blood flow and the curative effect.
5.Expert Consensus on Clinical Diseases Responding Specifically to Traditional Chinese Medicine: Sjögren's Syndrome
Jing LUO ; Yuan XU ; Xinyao ZHOU ; Mengtao LI ; Xiujuan HOU ; Hailong WANG ; Hua CHEN ; Qin ZHANG ; Yan GENG ; Jinxia ZHAO ; Yi ZHAO ; Miansong ZHAO ; Jiabo WANG ; Yong WANG ; Xiaoxiao ZHANG ; Qingwen TAO
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(8):73-79
Sjögren's syndrome (SS), a disorder of immune system, is one of the dominant diseases treated by traditional Chinese medicine (TCM). China Association of Chinese Medicine organized experts in the field of TCM and western medicine rheumatology and pharmacology to discuss the advantages and optimal regimens of TCM for the treatment of SS. The experts generally agreed on the low early diagnosis rate of SS and the lack of targeted therapeutic drugs. In addition, autoimmune abnormality is the key factor in the occurrence of SS and deficiency of both Qi and Yin is the core pathogenesis. SS has unique tongue manifestations, which is expected to allow for the early diagnosis and treatment with integrated traditional Chinese and western medicine. TCM has advantages in treating SS in terms of alleviating clinical symptoms and systemic involvement, individualized treatment, relieving sleep and mood disorders, preventing the occurrence in the early stage, and enhancing the effectiveness and reducing toxicity in the treatment by integrated TCM and western medicine. In general, TCM has advantages in different stages of SS. Internal and external use of TCM, acupuncture, and acupotome are all available options. The optimal regimens should be determined on the basis of pattern identification, stage of disease, and the advantages of TCM. Clinical characteristics and biomarkers of SS should be studied to classify patients, so as to design precision evidence-based TCM regimens for SS. On the basis of unique tongue manifestations of SS, models for early diagnosis and poor prognosis identification of SS should also be established to achieve early prevention and treatment and to improve the prognosis. In the future, we should vigorously carry out high-quality evidence-based medical research on the treatment of SS by TCM and integrated traditional Chinese and western medicine and develop relevant guidelines to optimize and standardize current diagnosis and treatment, thereby laying a basis for clarifying and explaining the advantages of TCM in treating SS.