Unilateral neglect is one of the common advanced neurological deficits of stroke. This article highlights the post-stroke definition of unilateral neglect, incidence, sites of lesion resulting in neglect, possible mechanisms and clinical manifestation. It overviews the typing and complications of unilateral neglect, and points out that the significance on the assessment and treatment of unilateral neglect.

Objective:To study the dose measurements methods of neutron andγ-ray for 252Cf neutron after-load radiotherapy machine. Methods:To measure the neutron-γmixed field with one ion chamber that have the similar sensitivities of neutron andγ-ray, another ion chamber that only have sensitivities for γ-ray, little sensitivity for neutron. Verification measurement results with calculated values. Results:Calculate key parameters, measure neutron andγ-ray dose rate at the position of 2.5cm, 5cm, 7.5cm and 10cm from the 252Cf, the Maximum deviation is-5.22%compared with calculated values. Conclusion:The method of twin ion chamber can measure the neutron andγ-ray mixed field dose.

Unilateral neglect is a common and advanced nervous disorder of stroke, well-recognized predictor of poor neural functional outcome following stroke. There are several rehabilitation Methods including sensation input, visual scanning training, vestibular stimulation, head and trunk rotation, suggestive therapy, environmental adaptation and activities of daily living training, and some new therapies including prism adaptation, constraint-induced movement therapy, eye patching and transcranial magnetic stimulation developed in the past few years, which to some extent are effective on the treatment of neglect.

Objective To study the quality testing of dose delivery system of the active spot scanning proton and heavy ion accelerator,in order to provide the reference for the quality control of related equipment.Methods In the four therapy rooms,both 0.6 cc chambers and Gafchromic EBT3 films were used,respectively,to test the accelerator for dose reproducibility,dose linearity,dose stability,depth dose distribution,beam scanning position deviation and radiation field uniformity in each therapy room.Results Dose reproducibility variation coefficients are all less than 1.5％,dose linearity's maximum deviations less than 2％,dose stability's deviations less than 2％,depth dose distribution stability within 2％,beam scanning position deviation less than 1 mm,consistency of irradiation field's deviation less than 2 mm,and flatness within ± 5％.Conclusions The indicators about quality testing for the active spot scanning proton and heavy ion accelerator are all in line with the requirements of IEC standards draft.

Objective To develop the method for testing the consistency of irradiation field produced by the active spot scanning proton and heavy ion accelerator.Methods Calibration of the EBT3 films were carried out with the calibrated ion beam to establish the dose calibration curve.According to the different proton and carbon ion energies (proton:94.29,150.68,212.62 McV;carbon ion:175.99,283.43,412.54 MeV/u),EBT3 films were located in the solid water phantoms in each therapy room,respectively.Finally,the irradiated EBT3 films were scanned and the radiation field size's deviation and flatness were analyzed.Results In different conditions,radiation field size's deviations were all less than 2 mm and the flatness parameters were all controlled below the 5％.Conclusions EBT3 films can be used to test the active spot scanning proton and heavy ion accelerator's radiation field uniformity.

OBJECTIVE:To establish an ion-pair RP-HPLC method for determination of the concentration of netilmicin sulfate in human serum.METHODS:The determination was performed on Luna C18 column with column temperature set at 40℃;the mobile phase consisted of acetonitrile-water (15∶85,pH 2.0,containing 10 mmol?L-1 sodium heptanesulfonate) at a flow rate of 0.8 mL?min-1.The detection wavelength was set at 205 nm.RESULTS:The linear range of netilmicin was 2～20 mg?L-1(r=0.997 6) with a recovery rate of 93.66%～96.05%.The intra-day and inter-day RSD were both less than 10%,respectively.CONCLUSION:The method is sensitive and simple with accurate and reliable results,and it is able to satisfy the requirement for the determination of serum concentration of netilmicin.

Famotidine ( Fam ) antagonized the effects of histamine on guinea pig atria and rat uteri MI vitro non-competitively,however the antagonisms of Ranitidine(Ran) and Cimetidine (Cim ) on hoistamine were competitive, their pA2 were 6. 24, 5. 16 and 4. 08 for guinea pig atria , 8. 26, 7. 22 and 6. 17 for rat uteri respectively. They reduced gastric secretion of acid and pepsin of pylorus ligated rats in dose-related manner, inhibited gastric secretion stimulated byhistamine, prevented the acute gastric lesion from stress, indomethacin and histamine, and enhanced the healing process of chronic gastirc ulcerinduced by acetic acid in rats. Moreover, Fam was much more potent than Ran (6~8 times) and Cim(30 - 40 times). Besides,Cim increased hypnotic effect of phenobartal, but Ran and Fam had no or Ittile such effects.

Objective To evaluate the efficacy of ultrasonically guided radiofrequency (RF) thermal ablation of hepatic carcinoma (HC) with a clustered electrode. Methods Clinical records on 245 consecutively admitted HC patients who underwent RF tissue ablation therapy were analyzed. The tumor supplying blood flow, changes of tumor size, clinical manifestation, and AFP level were analyzed. Results AFP value decreased significantly in 50% of patients one week after ablation. Tumors less than 5*!cm in diameter became avascularized 1 to 6 months after the therapy, and it was noted that all tumors shrank in size after the therapy. For tumors more than 5*!cm in diameter, RF ablation was used in conjunction with intraarterial chemotherapy and embolization. Conclusion Ultrasound guided RF thermal ablation is an effective, safe, minimally invasive technique for treating malignant hepatic tumors.

Statins not only reduce the incidence of ischemic stroke but also have the neuroprotective effect on ischemic stroke. Experimental studies in recent years have found that the neuroprotective effect of statins is achieved by multiple mechanisms, in which the regulation of microvascular endothelial barrier is a new mechanism. This article reviews the advances in re-search on this mechanism.