Meta analysis system was used to evaluate the efficacy and safety of nourish serum brain granules in the treatment of hypertensive headache in clinical practice.Methods Searching CNKI，PubMed，Weipu and Wanfang databases，collecting literature from 2001 to 2020 on the treatment of nourish serum brain granules for hypertension and headache，and applying Review Mananger 5.3 for data analysis.Results In 11 articles，it was suggested that nourish serum brain granules could effectively relieve hypertensive headache after data analysis（RR=1.52，95%CI 1.41～1.64，P<0.00001），without obvious adverse reactions.Conclusion The clinical application of nourish serum brain granules for hypertension headache has obvious efficacy and less side effects，and explains that its pathogenesis may be related to cerebrovascular spasm，due to the lack of high quality of the included literature and small sample size，more RCT validation is needed.

ObjectiveTo investigate effect of conducting training of autism spectrum disorder （ASD） early screening skill on improving the ability to early identify ASD of medical staffs in primary care hospitals. MethodsIn September 2021， the training of ASD early screening skills was carried out for medical staffs from 20 primary care hospitals in Chengdu. After training， the training effect was evaluated. The numbers of referrals from primary care hospitals to superior hospitals， confirmed ASD as well as their average diagnostic age of children with ASD before and after training were used as evaluation indicators. ResultsAfter training， the number of children with suspected ASD referred by primary care hospitals was more than that before training ［（16.65±11.60） vs. （3.40±2.23）， t=5.431， P<0.01］， the number of children diagnosed with ASD was more than that before training［（6.85±4.93） vs. （2.45±1.67）， t=4.171， P<0.01］， and the differences were statistically significant. As for the diagnosed age of ASD children， after training， the average age was lower than that before training ［（34.95±11.67） vs. （42.2±14.64）， t=-2.553， P=0.019］. ConclusionTraining of ASD early screening skills for medical staffs in primary care hospitals may help to improve their ability to early screening ASD children.