1.Significance of Prescription Analysis in Chinese Drugs Dispensing
China Pharmacy 2007;0(27):-
OBJECTIVE:To discuss the significance of prescription analysis in Chinese drugs dispensing and to probe into the profound connotation of the dispensing of prescriptions of traditional Chinese medicines.METHODS:Take the basic theory of Chinese medicine as the basis,the importance of prescription analysis in the dispensing of traditional Chinese medicines were analyzed from aspects of the patients' clinical diagnosis,medication intention as well as the function and properties of drugs etc.RESULTS:8 essential factors were found to be involved in prescription analysis,which shed new light on the omnidirectional pharmacy care provided for patients.CONCLUSION:The key for Chinese drugs dispensing lies in the prescription analysis.
2.A New Ventilation Mode with Simple Self-made Oxygenation Respirator
Fanxin MENG ; Jingxue HU ; Xia JIANG ; Lizhe DI ; Yufen DU
Chinese Medical Equipment Journal 2003;0(12):-
Objective To improve the ventilation mode for respiratory failure based on the self-made respirator. Methods For the conscious COPD patients with type II respiratory failure, nasal mask and NEEP ventilation mode were used. Patients breathe in air through the mouth and breathe out through the noses. There is no need of manual control tube to control the negative pressure in the nasal mask. For the non-typical type I respiratory failure, exhaled gas comes out from the one-way channel in the front of the mask, while oxygen for the next breathes is brought into the ball through the tube under it. Results The COPD patients breathe more freely and smoothly without disturb of the manual control tube. On the non-typical type I respiratory failure, FiO2 is much higher and without breath in CO2. Conclusion The new ventilation mode can provide a great range of FiO2 and get ride of redundant CO2. It's beneficial to the recovery of patients.
3.Development and application of simple oxygenation respirator
Chengli XU ; Xia JIANG ; Jingxue HU ; Tao LU ; Shijin PAN
Chinese Medical Equipment Journal 2003;0(12):-
Simple oxygenation respirator is mainly used for respiratory failure patients who are failed in being treated with open positive pressure.It can markedly improve the oxygenation concentration and ventilation.Most respiratory failure patients can avoid using mechanical respirator if it is used adequately.Respiratory model Ⅰ,Ⅱ,Ⅲ can be applied according to different type of respiratory failure respectively.It is also very effective to cerebral vascular diseases.The structure of respirator is fit for human physiology without interfering cardiac and pulmonary functions.It has no contraindications and side effect.It is simple,cheap and practical.
4.Advances in pharmacological effects of Traditional Chinese Medicine hops
Jingxue LIU ; Yu JIANG ; Hehui XIE ; Jin HUANG
Journal of Pharmaceutical Practice 2019;37(1):5-8,13
The Hop plant (Humulus lupulus L., Cannabinaceae) is a dioeciou twining perennial.The relevant papers at home and abroad in recent years were reviewed and a summary analysis and induction were conducted to research the progress of hops and provide a basis for further development and application of the medicinal materials.Pharmacological effects of hops were reviewed, which found that hops have a good research prospect and deserve further promotion and development.
5. Analysis of gene mutation in the interaction domain of head and stalk of Newcastle disease virus hemagglutinin-neuraminidase glycoprotein
Zhankui CAO ; Ying LIU ; Miaomiao CHI ; Jingjing JIANG ; Jingxue LIU ; Hongling WEN ; Li ZHAO ; Lianli CHI ; Zhiyu WANG
Chinese Journal of Experimental and Clinical Virology 2018;32(5):463-468
Objective:
To identify the function of 91-112 amino acids (aa) fragment, the interaction domain of head and stalk of Newcastle disease virus(NDV) HN glycoprotein, and clarify the role of the fragment in promoting cell specific membrane fusion.
Methods:
The specific gene sequences were identified by aligning 91-112 amino acids of NDV HN protein with amino acids of MeV H, RSV G, hPIV3 HN protein. The fragment deletion, fragment substitution and intermolecular homologous recombination method were combined to construct the deletion mutant, De(HN), and three chimeras, Ch(MeV), Ch(RSV), Ch(hPIV3). Cationic transfection reagent was used to transfect the plasmids into baby hamster kidney cells (BHK-21), in which vaccinia virus-T7 RNA polymerase expression system was expressed. Indirect immunofluorescence assay (IIFA) and flow cytometry (FCM) were executed to analyze the cell surface expression level. Cell fusion promotion activity, receptor recognition activity and neuraminidase activity of each mutant were also detected.
Results:
Cell surface expression efficiency of De(HN) and Ch(MeV), Ch(RSV), Ch(hPIV3) proteins were 9.04%, 82.20%, 70.16%, 75.65% of that of wild-type (wt) HN. Fusion promotion activity of De(HN), Ch(MeV), Ch(RSV), Ch(hPIV3) were 3.83%, 24.76%, 29.42%, 57.84% of that of wt HN. The fusion promotion activity of De(HN) almost disappeared and syncytium couldn’t be found under the microscope. Hemadsorption activity was 13.48%, 36.25%, 34.93%, 65.22%, respectively (