Objective To evaluate the efficacy of CO-2 laser treatment for patients with precancerous laryngeal lesions.Methods Ninety-four patients with precancerous laryngeal lesions were treated by endoscopic CO-2 laser operation from 2001 to 2006.87 males and 7 females patients had ages between 18 and 85.Results For a follow up ranging from 6 month to 5 years,the outcomes of 81 patients(81/94,86.2%) were successful only through one operation while 10 cases(10/94,10.6%)received more than two operations.The lesions for 3 patients(3/94,3.2%) were found to have turned out malignant at a later stage.Conclusion The carbon dioxide laser has proved valuable in treating patients with precancerous laryngeal lesions.