1.ON THE BIOCHEMICAL ACTION AND RADIORESISTANT ACTIVITY OF POLYSACCHARIDES EXTRACTED FROM RADIX BUPLEURI AND POLYPORUS UMBELLATE(PERS.)
Baozhang LU ; Zhongchen WU ; Jingrui SHAN ; Yuanji XU
Medical Journal of Chinese People's Liberation Army 1982;0(01):-
Polysaccharides extracted from radix of Chinese DC and dried Polyporus umbellate (pers) as well as a well known mitogen,phytohemagglutinin(PHA),were studied.It has been revealed that both the poly-saccharides as well as PHA stimulate the rate of DNA synthesis characterized by their increasing the incorporation of 3H-TdR and accelerating the release of thymus cells. These effects disappeared after adrenalectomy.Corticosterone concentration was found to be increased in the plasma after the administration of the polysaccharides These phenomena suggested that the adrenal cortex was the mediator of their actions. When they were administered to animals before an irradiation of 800 rad, the survival rate was increased by 30-70% over that of the controls. The mechanism of the effects was discussed.
2.THE CHANGES OF RECEPTORS IN THE LUNG TISSUE OF EXPERIMENTAL ALLER-GIC ASTHMATIC GUINEA PIGS.
Baozhang LU ; Tao LI ; Jingrui SHAN ; Zhentu CHEN
Medical Journal of Chinese People's Liberation Army 1982;0(01):-
A model of experimental allergic asthma was induced by sensitizing and challenging guinea pigs with egg albumin. The changes on the concentrations and affinities of ?2,? adrenergic and muscarinic receptors as well as the content of cyclic adenosine monophosphate in lung tissue of the asthmatic animals were investigated and compared with the values obtained from normal animals respectively. The results showed that the maximal binding volume of ? receptor as well as the content of cAMP decreased significantly, while the concentrations of ?2, receptor and M receptor increased. It is well known that the ? receptor mediates a process resulting in the relaxation of bronchial smooth muscle by stimulating adenylate cyclase and therefore, increases the cytoplasmic concentration of cAMP. whereas the ?2, and M receptor mediate processes resulting in the contraction of smooth muscle through quite different mechanisms. The significance of the two kinds of change operating towards opposite direction in the pathogenesis of allergic asthma was discussed.
3. Exploration and implementation on the mode of undergraduate community nursing practice, according to "National Standard of Undergraduate Teaching Quality"
Jingrui XU ; Guiming YAN ; Shan ZHAO ; Chunmei WANG ; Yue ZHAO ; Qi LU
Chinese Journal of Practical Nursing 2019;35(22):1681-1684
According to 'National Standard of Undergraduate Teaching Quality for Nursing Science', the mode of community nursing practice was explored and implemented by the School of Nursing in Tianjin Medical University. Focus on competency, the syllabus of community nursing practice was revised. Optimizing the management system of community nursing practice, developing the team of high-quality teachers, building standardized community nursing practice bases, and improving the evaluation system of community nursing practice aimed to enhance comprehensive quality of nursing undergraduates and the quality of community nursing practice. Within the concept of "big health", our school is exploring the new mode of combining community nursing practice with health management-oriented nursing personnel training, which lays an important foundation for training applied nursing talents to meet the needs on development of community health services.