1.Effect of Creatine Phosphate Sodium on Postoperative Fatigue in Gastric Carcinoma Patients
Xixia XU ; Bibo TAN ; Jingmiao WEI ; Min WANG ; Lingling WANG ; Yong LI
Tianjin Medical Journal 2014;(8):830-833
Objective To investigate the effect of creatine phosphate sodium on postoperative fatigue syndrome (POFS) in gastric carcinoma patients. Methods Nighty cases of radical resection in gastric cancer were randomly divided into control group (n=45) and treatment group (n=45).Normal saline (100 mL) and phosphocreatine sodium (2 g) was admin-istrated intravenously after anaesthesia induction in treatment group while only normal saline was given in control group . After operation, the two groups of patients were all treated with enteral and parenteral nutrition. General performance was ob-served in both groups. Fatigue score (VAS score) was measured on the day before the operation,the first,third and fifth day after operation. Body weight, triceps skinfold thickness (TSF), mid upper arm circumference (AMC), plasma total protein (TP), plasma albumin (ALB) and prealbumin (PA) were examined at the same time. Results The total effective rate of the control group and the study group were 73.3%and 95.6%respectively and the difference was of statistically significant. Fa-tigue scores (VAS score) was significantly difference in both groups pre- and post-operation time points, also between 2 groups. Body mass, TSF and AMC in time points postoperation were all lower than those in the time point of preoperation. TP, ALB and PA of two groups in postoperative time points were significantly different compared with those in preoperative time point. The above indexes were all decreased with postoperation time, and these indexes in treatment group were signifi-cantly better than those in control group. Conclusion Creatine phosphate sodium can alleviate postoperative fatigue, im-prove nutritious status and promote early rehabilitation of patients.
2.A standardized management model of anesthesia for painless digestive endoscopy
Jie FENG ; Wen LI ; Xin LI ; Mo DONG ; Shuying WEI ; Jianguo WU ; Lei SHI ; Hua LIU ; Jingmiao GENG
Chinese Journal of Digestive Endoscopy 2012;29(6):307-310
ObjectiveTo evaluate the safety and feasibility of the standardized management model of anesthesia for painless digestive endoscopy.MethodsData of 17 100 patients who underwent painless endoscopy were reviewed for severe adverse reaction and complications.The model included anaesthetist-directed appointment,nurse assistance during operation,and postoperative nurse observation.Eight hundred cases (200 of gastric endoscopy,intestinal endoscopy,EUS and ERCP respectively) were randomly selected and analyzed for times of endoscopic diagnosis,anesthesia,wakening and discharge,and complications.ResultsOf the 17 100 cases,severe complications occurred in 10 (0.058% ),including 3 apnea,one respiratory obstruction due to opisthognathism and glossoptosis,five larygneal spasm and 1 reflux inspiration.There was no anesthesia or endoscopy related death.Study of 800 cases showed intraoperative MAP,HR increase or decrease over 30% of the baseline,the incidence of SpO2 < 95% were 6.0% ~ 25.0%,3.0% ~8.5%,≤2.0%,respectively.The rate of lethe,good quality of sleep were 99% ~ 100% and 98.0% ~100.0%,respectively.The rates of cough,body movement and myoclonic were 0.5% ~4.5%,5.5% ~11.5%,and 1.5% ~ 3.5%,respectively.Rates of nausea and vomiting,excitement,restlessness and dizziness were lower than 4%.ConclusionThe standardized management model,feasible,safe and effective,is able to facilitate anesthetic efficacy and reduce complications.
3.Influence on vestibular function caused by acute low-tone sensorineural hearing loss.
Jingmiao WANG ; Junkuan WEI ; Xinxia JIANG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(1):25-30
OBJECTIVE:
To study the vestibular function of patients with acute low-tone sensorineural hearing loss (ALHL). So we can know whether their vestibular function was influence.
METHOD:
Vestibular function tests were performed on fifty-two ALHL patients by recording electronystagmography (ENG) and static posturography (SPG) before and after their therapy. Then made a comparison with normal.
RESULT:
Length of locus and velocity of postural sway of the ALHL subjects were significantly increased in comparison with normal (P < 0.05) when eyes closed. After therapy, two (3.8%) ALHL subjects were still recorded abnormal ENG results.
CONCLUSION
Most ALHL subjects without vertigo symptom, but their vestibular function was abnormal, so vestibular function tests should be performed on patients with ALHL.
Adolescent
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Adult
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Case-Control Studies
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Female
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Hearing Loss, Sensorineural
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physiopathology
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Humans
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Male
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Middle Aged
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Prognosis
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Vestibular Function Tests
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Young Adult