Objective To discuss differentiated thyroid carcinoma (DTC)postoperative lymph node metas-tasis and clinical use and the effect of 131 I treatment.Methods to185 patients with lymph node metastasis of DTC were selected by random sampling method.The standard 131 I treatment was administrated,ultrasound,CT and Tg chan-ges and imaging characteristics of 131 I treatment were evaluated the clinical curative effect was determined.Results Imaging changes:the whole group of patients,153 patients (82.7%)were effective.153 patients with effective treat-ment,105 cases examined LMDTC completely eliminate (56.8%),48 cases examination revealed narrowing (25.9%).Mere lymph node metastasis after treatment was better than that of patients with viscera metastasis,imaging examination results were statistically significant differences (χ2 =2.57,P =0.02).After treatment,imaging examina-tion result in patients with smaller lymph node was superior to that in the patients with relatively large diameter lymph nodes (P >0.05).Tg level changes:there was a significant reduction in the Tg 97 cases of 185 patients (51.1%), and general decline in 54 patients (29.2%).Tg improvement effect of patients with mere lymphatic metastasis after treatment was better than other viscera metastasis in patients with statistically significant differences (χ2 =3.41,P =0.01).Lymph node Tg improved after treatment in patients with small diameter,which was better than that with other viscera metastasis patients with statistically significant differences(χ2 =6.34,P =0.02).Conclusion Comprehensive curative effect of 131 I treatment of lymph node metastasis postoperatively in patients with DTC is distinct,and is worth popularizing in clinical use of DTC.

ObjectiveTo study the proper position for postoperative patients with retinal detachment by intraocular tamponade when using self-designed pillow. Methods Divided 70 postoperative patients with retinal detachment by intraocular tamponade into the experimental group and the control group randomly. The self-designed pillow was used in the experimental group, the routine nursing measures were used in the control group, and then compared the incidence rate of postoperative complication in the two groups, and evaluated the comfortable condition of the patients in the 2 groups. Results The postoperative condition in the experimental group were all better than those in the control group, P

OBJECTIVETo study the effect of epidermal growth factor(EGF) and different concentrations of gonadotrophin (Gn) on the in vitro maturation of human oocytes.

METHODSEGF was added to the vitro culture medium in order to observe the effect of Gn combined with or without EGF on the result of in vitro maturation. The concentrations of hCG and FSH were changed respectively to observe the difference between the results.

RESULTSAdding EGF to the culture medium improved the maturation rate of oocyte significantly (P < 0.05). There was no difference between the results with different concentrations of hCG and FSH in the culture medium.

CONCLUSIONEGF can improve the results of the in vitro maturation of human oocytes by increasing the maturation rate significantly. Increasing the concentration of Gn does not influence the results of in vitro maturation.

Cells, Cultured ; Dose-Response Relationship, Drug ; Epidermal Growth Factor ; pharmacology ; Female ; Fertilization ; drug effects ; Gonadotropins ; pharmacology ; Humans ; Oocytes ; drug effects ; physiology

Objective To observe the effect of two different chemotherapy regimens, including irinotecan, folinic acid and FU chemotherapy regimen (FOLFIRI) versus folinic acid, FU and oxaliplatin chemotherapy regimen (mFOLFOX6) on nutritional status in patients with advanced colon cancer. Methods A total of 110 patients with advanced colon cancer in Shanxi Cancer Hospital were divided into FOLFIRI (group A) and mFOLFOX6 (group B). To investigate the effect of two different regimens on the patients with advanced colon cancer by toxicity, the traditional methods of nutritional assessment, scored patient-generated subjective global assessment (PG-SGA), nutrition risk screening-2002 (NRS-2002). Shapiro-Wilk was used to detect the normality of small samples, t test was used to analyze measurement data conformed to the normal distribution, Wilcoxon non-parametric test was used to analyze the abnormal distribution data, and enumeration data was detected by using chi-square test. Results The incidence of vomiting, diarrhea and alopecia in group A and group B was respectively 53.8 % (28/52) vs. 29.3 % (17/58), 65.4 % (34/52) vs. 43.1 %(25/58),46.2 %(24/52)vs.20.7 %(12/58)respectively,and there was a significant difference(all P <0.05). The albumin, body mass index, NRS-2002 score, PG-SGA score after chemotherapy were significantly lower than those before chemotherapy in both groups (all P < 0.05). PG-SGA scores after chemotherapy in group A and group B were respectively 7.0 and 5.5 (Z= -2.026, P< 0.05). There were no statistically significant differences between the two groups in the albumin, body mass index, triceps skin fold (TSF), arm muscle weeks diameter(MAMC)and NRS-2002 score(all P >0.05).Conclusions FOLFIRI and mFOLFOX6 scheme can reduce the patient's nutritional status. The probability of gastrointestinal adverse reaction of FOLFIRI regimen is high, which may have an obvious impact on nutritional status of patients compared with mFOLFOX6 scheme.

Objective To evaluate the rehabilitation efficacy of music training in pediatric cochlear implants (CIs).Methods The 14 subjects were divided into the training and control groups.The age of the training group was 5 to 8 years old,with an average of 6.12±1.46.The age of the control group was 5 to 7 years old,with the average of 5.86±0.90.The subjects in the training group received speech rehabilitation training together with music training,while those in the control group only received speech rehabilitation training.We performed an analysis to compare the music perception,speech perception,mental state,and the quality of life between the two groups before and after training.Results For training group,the score of social anxiety scale for children(SASC) was 11± 3.27 before training,and 15.71±1.89 after training;the score of note discriminate test was 30.86±13.61 before training,and 42.29± 13.24 after training.For control group,the scores of SASC was 12.71±2.93 before training,and 14.57±3.51 after training;the pre-training score of note discriminate test was 33.14±11.48,and post-training score was 36.57± 10.44.After training,the scores of the two test items in training group were significantly higher than those in control group (P＜0.05).Conclusion Not only does music training promote music and speech perception in pediatric CIs,it also has proved to be an effective psychological construct for the hearing-impaired children that helps develop self-confidence and improve social status.Moreover,children's improvement in hearing and emotional well-being helps alleviate the psychological stress and anxiety experienced by the children's parents.