OBJECTIVE:To improve the quality of drug consultation.METHODS:The drug consultation records of a total of 1 663 cases in our hospital from July 2004 to July 2007 were analyzed statistically by a retrospective method.RESULTS:Of the drug consultation records of a total of 1 663 cases,the chief questions consulted were adverse drug reactions and long-term medication safety(25.2%),dosage and administration(21.1%),medication for special populations(9.7%),drug interactions(8.1%),pharmacological action and indications(7.1%),and generic name and composition of drugs(5.2%).CONCLUSION:The drug consultation service in our hospital achieved a remarkable efficacy in guiding physicians and pharmacists on rational drug use;however,it has its problems and remains to be improved further.

OBJECTIVE:To probe into the effects of ?-1bIFN on the development process from the hepatitis gravis to postnecrotic cirrhosis.METHODS:The change of serum liver fibrosis markers and hepatic function were observed in treatment group and control group before and after treatment.RESULTS:(1)In treatment group,all the serum liver fibrosis markers were decreased after treatment and were significantly different from those in control group(P0.05).(2)After treatment,the levels of serum albumin,globulin and count of platelet reverted to normal in treatment group and the levels were significantly different from those in control group(P

OBJECTIVE: To evaluate the efficacy and safety of diammonium glycyrrhizinate in the treatment of drug-induced liver injury according to present clinical studies. METHODS: Retrieved from CBM and the CNKI from 1994 to 2009, literatures about the randomized controlled trials that the effective rate of diammonium glycyrrhizinate was compared with that of other hepatoprotective with drug-induced liver injury and drug-induced liver disease as study subjects. RESULTS: 18 RCTs including 1,644 patients with drug-induced liver injury were enrolled. The effective rate of diammonium glycyrrhizinate group was higher than that of control group, statistical significance was noted in two groups (P

Objective To value the application of surface electromyography(sEMG)in assessing the functional electrical stimulation(FES)used in children with spastic diplegia.Methods 20 children with spastic diplegia were treated with FES.They were assessed with the sEMG and the clinical assessment before and after treatment.Results After treatment,the iEMG of the biceps brachii and quadriceps decreased significantly on the functional position,but increased significantly when the muscles contracted.Conclusion FES can reduce the spasticity and increase the strength of the limbs in children with spastic diplegia.The sEMG can be used as an objective assessment tool.

USA is the first country implementing the UDI program at national level,and the UDI rules and GUDID guidance have been issued by FDA recently to officially launch the implementation of UDI. The paper reviewed the advancement of UDI program,dis-cussed the framework of UDI system,analyzed the approaches of UDI implementation such as accredited issuing agencies and GUDID et al, and made some suggestions on the development of medical device coding system in our country.

The article has summarized the situation related to medical device naming, analyzed the problems of medical device naming in our country, put forward some new thinking in building the naming system of medical device in our country provided some reference on technical study of medical device naming.
China ; Durable Medical Equipment ; classification ; Terminology as Topic

The article has reviewed the administration technical structure and global application of the global medical device nomenclature(GMDN), analyzed the coordination between GMDN and the industry status of medical device in our country, put forward some suggestions on the applicaition of GMDN, provided some reference on raising the management level of medical device in our country.
Equipment and Supplies ; standards ; Terminology as Topic

OBJECTIVE:To evaluate the clinical efficacy of Xuebijing injection in treating acute paraquat poisoning.METHODS:35 patients with acute severe parquat poisoning who were admitted into ICU of our hospital from Jan.2002 to Apr.2008 were enrolled in our study:15 cases were assigned to control group,20(treatment group)received Xuebijing 100 mL bid for 7～10 d in addition to the therapy as in control group.RESULTS:Liver enzyme and creatinine levels in both group were reduced,with the level in the treatment group significantly lower than in control group(P

Objective To investigate the clinical efficacy of recombinant human epidermal growth factor in the treatment of recurrent oral ulcers in elderly patients.Methods 82 cases of elderly patients in our hospital in the treatment of recurrent oral ulcer were selected,41 cases in the control group,the conventional western medicine treatment,41 cases of the study group,recombinant human epidermal growth factor in treatment before and after treatment,blood determination of immune status,clinical efficacy and adverse reactions of comparison were performed at one-year follow-up.Results the effective rate of treatment group is lower than 78.05％of the effective rate of treatment group 95.12％,study group 3,6 and 12 months recurrence rate(4.88％,7.32％,7.32％)than in the control group the recurrence rate(19.51％,24.39％,29.27％),the study group after the treatment of CD3+ and CD4+/CD8+ and NK were higher than the control group,the CD8+ level is lower than the control group(P<0.05),the two groups had no serious adverse reaction.Conclusion recombinant human epidermal growth factor is effective in the treatment of oral ulcer.

The inducible c-myc antisense RNA expression plasmid PGXC expressed in mammalian cells was constructed. PGXC was cotransferred with plasmid pSV2neo which confers resistance to Geneticin (G418) to human promyclocytic leukemia cell line HL60. Following the promotion of c-myc antisense RNA expression with Cd~(2+) the growth rate of transfectant HL_(60)~R-9 was significantly slower than that of the parent cells HL60. Flow cytometric analysis indicated a marked increase in Gl fraction and decrease in S-phase population in the cell cycle of transfectants. The differentiation of cellular morphology and function of HL_(60)~R-9 was induced. HL_(60)~R-9 did not form colonies on soft agar and had reduced or lost the tumorigenicity in nude mice.