Objective To observe the clinical efficacy and adverse reactions of tissue-selecting therapy stapler with internal hemorrhoids.Methods Clinical and follow-up data of 110 cases with internal hemorrhoids undergoing tissue-selecting therapy stapler between March 2011 and March 2012 were retrospectively analyzed.The efficacy,adverse reaction and the complications were assessed.Results Of the 110 patients,Ⅱ degree hemorrhoids in 21 cases,Ⅲ degree hemorrhoids in 63 cases,Ⅳ degree hemorrhoids in 26 cases.The mean operation time was 18 minutes,range 15 to 25 minutes.The mean hospital stay time was 4 days,range 3 to 6 days.Of the 90 patients,urinary retention 9 patients (8.18％),anal bulge 41 patients(37.27％),fecal urgency 8 patients (7.27％),no other complications found,such as postoperative bleeding,anorectal stenosis and fecal incontinence.Recurrence rate was 4.55 ％ within a year follow-up.Conclusions Tissue-Selecting Therapy stapler for internal hemorrhoids is a simple and safe procedure with less intraoperative and postoperative bleeding,low recurrence rate,fewer postoperative complications and so on.It's worthy of clinic application.

Objective: To observe hypoglycemic effects of Yunu Decoction, Zuogui Pill and Shenqi Pill, three compound traditional Chinese herbal medicines, in treatment of diabetes mellitus induced by alloxan in rats, and to compare the therapeutic effects among the three recipes for nourishing yin, clearing away heat, and nourishing yin and warming yang. Methods: Diabetes mellitus was induced in rats with alloxan at a dose of 60 mg/kg via tail vain injection. The diabetic rats were randomly divided into four groups: alloxan model group, Yunu Decoction-treated group, Zuogui Pill-treated group and Shenqi Pill-treated group. Rats in the three recipe groups were administered intragastrically with water extraction of Yunu Decoction, Zuogui Pill, and Shenqi Pill accordingly for 10 days. Then the level of blood glucose was measured by glucose oxidase method and the glucose tolerance was determined. Results: Compared with the normal rats, blood glucose level in the alloxan model group was obviously increased (P<0.05). Glucose levels in the three recipe groups were obviously decreased as compared with the alloxan model group (P<0.05), and glucose level in the Yunu Decoction-treated group after treatment was significant lower than before treatment (P<0.05). The glucose tolerance test indicated that rats in the alloxan model and three recipe groups revealed impaired glucose tolerance as compared with the normal rats, and there were no significant differences between the alloxan model group and the three recipe groups. Conclusion: Yunu Decoction, Zuogui Pill and Shenqi Pill can effectively decrease the glucose level of the rats with diabetes mellitus induced by alloxan, and Yunu Decoction showed the best therapeutic effects. The glucose tolerance test shows that the three recipes cannot correct the abnormal metabolism of glucose.

Objective To detect the urinary albumin level and urinary albumin/urine creatinine ratio in patients with acute cerebral infarction and explore their relations with NEW-TOAST typing.Methods One hundred and sixty-eight patients with acute cerebral infarction,admitted to our hospital from March 2011 to March 201,were chosen in our study; and other 45 healthy subjects were used as controls; according to NEW-TOAST typing,the patients were divided into different subgroups.Their clinical data were retrospectively analyzed; the 24 hour urinary albumin level and urinary albumin/urine creatinine ratio were detected and their relation was analyzed between patient group and controls,and between patients of different subtypes; besides,the correlation of neurologic impairment (NIHSS) scores with urinary albumin/urine creatinine ratio was analyzed.Results The 24 hour urinary albumin level and urinary albumin/urine creatinine ratio was positively correlated (r=0.301,P=0.001); according to the NEW-TOAST subtypes,patients with large artery atherosclerosis and small artery occlusion had significantly higher level of 24 hour urinary albumin level and urinary albumin/urine creatinine ratio (P＜0.05).NIHSS scores and urinary albumin/creatinine ratio in patient group were positively correlated (r=0.215,P=0.001).Conclusion Acute cerebral infarction and kidney disease are closely correlated;both 24 hour urinary albumin level and urinary albumin/urine creatinine ratio can be the predictor of acute cerebral infarction and influence the prognosis.