Objective To discuss the possibility and efficiency by using Six Sigma method.Methods By using"five steps" of Six Sigma,management of medical consumable materials storehouse was improved continuously.Such Sigma levels before and after the implementation in 6 months were compared as satisfaction for medical service,supply punctuality,rate of high-quality products,and the realization of"Zero Storage".Results All Sigma levels were raised.Conclusion The method of Six Sigma fits for the storehouse management of medical materials and can improve the management quality.

Objective:The effect of Wireless Analgesia System for the patients with postoperative pain, chronic pain and cancer pain in Anesthesiology Department will be discussed in this article. Methods:With the wireless signal being sent from the analgesia terminal transmitter to the base station of analgesia control, the analgesia pump can be connected with wireless analgesia terminal. Drugs can be delivered persistently or intermittently to keep the plasma concentration in an appropriate level according the vested parameters from the wireless system of analgesic delivering. Results:The information from the patients in the process of analgesia can be processed and saved by the system. According to the information of running and alarm displaying at the monitoring station, the analgesia records can be kept automatically. Conclusion:The satisfaction degrees on analgesia treatment can be improved, and the burden of work for anesthesiologists can be lessened as well, which improve the quality of medical services and promote the development of informatization in anesthesiology department.

Objective: To design a set of digital medical record MIS. Methods: According to the problems of paper-based medical records management, the protocol of digital medical record MIS using micro-digital imaging technology was proposed. Results:It realized electronic medical record storage, the front page information of medical records, medical record circulation and statistics of medical information. Conclusion: The storage of paper based medical record was effectively compressed, the information level of medical record management was clearly promoted after using the digital medical record MIS. It realized the conservation and usage for current medical records, guaranteed information security and data sharing etc.

Objective Traditional outpatient process has been blamed for its complexity and inconvenience .The ariticle was to evaluate the effects of incorporating mobile internet into our hospital's queuing system . Methods The outpatient queuing data of Nanjing General Hospital of Nanjing Military Region were collected .Four indexes are proposed to evaluate the quality of medical serv-ice in the hospital , including the average outpatient wait time , the average outpatient interview time , the ratio of interview time to wait time, and the number of outpatient stayers . Results These indexes predicted that approximately 38.08%of outpatients would ben-efit from the application of mobile internet to queuing service , the average outpatient wait time would reduce by 42.31% and that 25.60%of the outpatient stayers would decrease . Conclusion The system can shorten the wait time , decrease the number of stayers, improve the outpatient process and raise the utilization rate of medical resources .

Objective: To study the effect on cytotoxicity and drug resistance by blocking ERCCl gene expression in o-varian cancer cell lines. Methods: ERGC1 antisense expression vector was constructed and transfected into human ovarian cancer cell lines. Northern blotting and Western blotting were used to detect the RNA and protein expression level in the cells. Luciferase assay system was used to reveal the host cell reactivation function. MTT assay was used to study the effect on cytotoxicity and drug resistance in the cell lines. Results: After transfection of the antisense ERCCl, Northern and Western blotting indicated that the RNA and protein expression level of ERCCl was obviously decreased. Luciferease assay showed reduced DNA-damage repair capacity as assessed by host cell reactivation. MTT assay also showed decreased drug resistance to cisplatin in the lines. Conclusion: Transfection of antisense ERCCl may enhance the cisplatin cytotoxicity by disturbing the NER pathway in cisplatin-resistant cell lines.

The traditional independent methods can not solve the prominent problems of long waiting time in registration , paying and drug obtaining and short time in diagnosis and treatment .After the application of the mobile internet technology , it′s highly possible that outpatients′queuing congestion can be drastically alleviated .The paper investigates the outpatient registration and queuing data of our hospital over 9 weeks, and presents key requirements and system architecture of an outpatient service system based on mo -bile internet.To achieve the target, the hospital must make great efforts to improve online experience , optimize offline outpatient process, promote mobile internet service , and cultivate outpatient internet habits .

The construction of single wireless web platform is an important condition for the development of clinical informa -tion technology .The aim of this study was to explore the construction of wireless web platform in hospital and innovative applications of medical internet based on this platform .The medical internet was applied innovatively through the construction of multi -service wireless web platform .Based on the innovative application of medical networks such as cold chain system and transfusion monitoring system , special clinical requirements were fulfilled so as to improve medical safety and medical quality .The multi-service wireless web platform can realize the integration of multi-networks and multi-systems to avoid overlapping investment and redundant construction in hospital .

Medical consumable is widely used in disease diagnosis,treatment and health care,but its multifarious classifications show its weakness in management.Based on the research and analysis on the existing kinds of classifications,this article unifies practical application in hospital and proposes"null-stock"classification method under the management plan,which seems more scientific and reasonable.

An analysis method for requirement of medical consumptive materials on Kalman filter is put forward.An analysis mathematical model is established at first,its solution process is carried out at same time,and then an example using this solution is given according to the working practice.At last,the shortcomings using classical Kalman filter were discussed and a new method using adaptive Kalman filter was proposed.

Objective:To explore the influence of neuregulin- 1 (NRG-1)intervention on pacing threshold of low voltage area in rats after myocardial infarction.Methods:Myocardial infarction model of rat was established via an-terior descending coronary artery ligation.The 34 rats with myocardial infarction were randomly and averagely di-vided into two groups:NRG-1 group (received NRG-1peritoneal injection)and control group (received peritoneal injection of normal saline of the same volume).After two weeks,pacing thresholds were tested in low voltage area related with infarct in rats after myocardial infarction,and Cx43 (an integral membrane protein of the connexin family)expression was measured in low voltage area.Results:After drug intervention two weeks,compared with control group,there was significant reduction in pacing threshold [(1.466±0.503)V vs.(0.7167±0.194)V,P =0.002]in NRG-1 group;there was significant rise in Cx43 expression [(0.30±0.15)vs.(0.95±0.20),P <0.001] in low voltage area in NRG-1 group.Conclusion:Neuregulin-1 significantly reduces pacing threshold of low voltage area in rats after myocardial infarction,the mechanism may be related to increase Cx43 expression and improve e-lectrical conductivity of myocardial cells.