1.Clinical observation on binocular vision in patients with vertical muscle paralysis
Chinese Journal of General Practitioners 2009;8(8):568-570
t affect the near stereopsis, showing that increasing vertical fusion range shouled be a compensation for maintaining the binocular vision caused by vertical deviation.
2.Discussion and study of TCM project cooperation system based on Web
Li ZHANG ; Jinghui WEI ; Wei LI
International Journal of Traditional Chinese Medicine 2012;34(9):818-819
Focusing on such problems as relative isolated information resource,bad cooperation among project members,complex project management and process,and totally low efficiency,we put forward a based-on-Web cooperation and management mode for scientific research.This mode is convenient for project management,fulfills the high-performance share within the project members,increases the management efficiency and pushes about the information process for cooperation management of scientific research.
3.Design and development of institutional scientific research management information system
Changqin LI ; Jinghui WEI ; Dong WU
Chinese Journal of Medical Library and Information Science 2014;(11):65-67,74
After the institutional scientific research management at present was analyzed according to the literature investigation, expert consultation, comparative and comprehensive analysis, the following were advanced, including the principles, target, function module and structure module for institutional scientific research management infor-mation system , and realization of its functions using the J2 EE technology-based B/S framework .
4.Diagnosis and Interventional Therapy by Spiral CT in Rupture of Hepatocellular Carcinoma
Jinghui DONG ; Huaming WANG ; Junhua ZHANG ; Yongwu LI ; Wei MA
Journal of Medical Research 2006;0(01):-
Objective To investigate the diagnosis and the curative effects of interventional therapy by spiral CT in rupture of hepatocellular carcinoma(HCC). Methods 46 patients were checked by spiral CT and abdominal puncture of non-condensable blood. All the patients were treated by the transcatheter arterial embolization (TAE) with iodinated oil and/or gelatin sponge. Results Characteristic findings were detected in 31 patients,of which 7 patients were chiefly detected by spiral CT. The bleeding of ruptured HCCs was controlled effectively in all the cases treated by TAE without serious complications. Conclusion Spiral CT is susceptive to the diagnosis of the ruptured HCC. TAE can be the chiefly treatment in ruptured HCC with fewer serious complications.
5.Effect of simvastatin on gene expression of L-type calcium channels in mouse myocardium with myocarditis caused by coxsackievirus B3
Zhongxia DOU ; Ju WANG ; Zhengren WEI ; Jinghui SUN
Journal of Jilin University(Medicine Edition) 2006;0(01):-
Objective To investigate the effect of simvastatin on gene expression of L-type calcium channels(LCCs) of myocardial cells in BALB/c mice infected by coxsackievirus B3(CVB3) so as to study the therapeutic effect of simvastatin on viral myocarditis.Methods Sixty male BALB/c mice were divided into five groups randomly(n=12).Mice in viral control group and three groups of oral administration of simvastatin(10,30 and 90 mg?kg-1)were inoculated intrapritoneally with 0.2 mL of CVB3(Nancy strain).Mice in normal control group were inoculated intrapritoneally with 0.2 mL Eagle's solution.The heart samples of all the mice were obtained for hispathological study and detection of myocardial LCCs alpha1 subunits mRNA expression by semi-quantitative reverse transcription-polymerase chain reaction(RT-PCR).Results In viral control group,the mononuclear inflamematory infiltrate was focal or diffuse in myocardium of mice,severe hearts revealed a large area of myocardial necrosis.The degree of inflammatory cell infiltrate and area of necrosis were significantly less in simvastatin groups as compared with viral control group.The myocardial LCCs alpha1 subunits mRNA expression by semi-quantitative RT-PCR in normal control group was much lower than that in viral control group(0.06?0.01 vs 1.37?0.32,P
6.Clinical analysis of 314 children with chest pain
Yan ZHOU ; Sirui YANG ; Jinghui SUN ; Yongkang WEI ; Xiaoming LI
Chinese Journal of General Practitioners 2008;7(8):531-534
Objective To understand the cause of chest pain (precordium indisposition) in children and explore the thread of thought in its analysis.Methods Clinical data of 314 children with chest pain who visited the cardiovascular department for children of our hospital were collected and analyzed to study its causes.Results The cause could be attributed to organic cardiac diseases in 43 of 314 children (13.7%) with chest pain,to non-organic cardiac diseases in 108 (34.4%),to psychiatric-psychological factors in 60 (19.1%) and to unknown cause in 41 (13.1%).Average age of children with organic cardiac diseases was younger than that of children with other causes (P<0.05).Symptoms accompanied simultaneously in children with organic cardiac diseases were much more frequent significantly than those in them with non-organic cardiac chest pain and unknown causes (P<0.05).Conclusions Chest pain in children could be caused by a few causes,which was non-specific symptom for organic cardiac diseases,so, more should be taken into account in analyzing the cause of chest pain in children.
7.Effects of therapy with small volume of different fluids on renal blood flow in endotoxemia rats
Jinghui CHEN ; Hongyu PANG ; Jianqi WEI ; Gangjian LUO ; Ziqing HEI
Chinese Journal of Anesthesiology 2010;30(7):820-822
Objective To evaluate the effects of therapy with small volume of different fluids on renal blood flow in endotoxemia rats.Methods Thirty parthogen-free SD rats weighing 180-250 g were randomly divided into 5 groups (n = 6 each):group Ⅰ control; group Ⅱ LPS; group Ⅲ LPS + 7.5 % hypertonic saline (HS);group Ⅳ LPS + hydrozyethly starch (HES) 130/0.4 and groupⅤ LPS + hypertonic saline plus hydroxyethly starch (HS-HES) 40. The animals were anesthetized with intraperitoneal 3% pentobarbital 40 mg/kg. Left carotid artery was cannulated for BP and HR monitoring and fluid administration. In groupⅡ-Ⅴ LPS 1 mg/kg was administered via arterial cannula. In group Ⅲ, Ⅳ and V 4 ml/kg of 7.5% HS, HES 130/0.4 AND HS-HES 40 were administered via arterial cannula respectively at 30 min after LPS administration.In groupⅠ and Ⅱ normal saline 4 ml/kg was given insteadt. Renal blood flow was measured with Doppler ultrasound before LPS (T1 ,baseline), at 30 min after LPS (T2), 10, 30 and 60 min after fluid therapy (T3, T4, T5). The animals were then sacrificed and both kidneys were removed for microscopic examination with light microscope. Results Renal blood flow was significantly decreased and was significantly recovered to some extent by therapy with different fluids especially with HS-HES 40 in group Ⅴ. Conclusion Therapy with small volume of HS,HES or HS-HES could increase renal blood flow and inprove renal microcirculation especially HS-HES.
8.Multi-factor analysis of influencing factors of the self-care efficacy for PHC patients by transcatheter arterial chemoembolization of different age groups
Duo QIAN ; Wei DING ; Jinghui SHEN ; Yufang WU
Chinese Journal of Practical Nursing 2015;31(3):205-210
Objective The objective of this study was to explore the difference factors for PHC patients by transcatheter arterial chemoembolization of different age groups of senior people in China and support reference for individualized intervention by clinical medical workers.Methods 153 cases of PHC patients by TACE were selected by convenience sampling method from October 2013 to June 2014.The data were collected using general data questionnaire,Health Promotion Strategy Scale,QOL-LC,Memorial Symptom Assessment Scales and Social Support Scale to evaluate the physical,psychological and social aspects of the PHC patients.We divided the patients into young,middle-aged and elderly groups.Single factor and multiple factors regression analysis were used to compare the status and influencing factors.Results Psychological function,value of blood AFP,marital status entered the model and were self-care efficacy and correlated factors of young-aged patients,which could explain 50.6% of the total varience.Physical symptoms,exploitation degree of support and intervention treatment times entered the model and were self-care efficacy and correlated factors of middle-aged patients,which could explain 47.8% of the total varience.Symptom distress,degree of cuhural and psychological function entered the model and were self-care efficacy and correlated factors of elderly-aged patients,which could explain 42.4% of the total varience.Conclusions The self-care efficacy were low in all ages of PHC patients by TACE,it is associated with a variety of factors.Doctors and nurses should pay more attention to the self-care efficacy for PHC patients by transcatheter arterial chemoembolization with different age groups.Also we should evaluate and make well-targeted policies and personalized inter-ventions to promote self-management self-efficacy.
9.Correlation of hyperuricemia with factors of dietary and metabolic syndrome
Wei CHEN ; Yanping LIU ; Miao YU ; Jinghui FANG ; Fang MA ; Hongding XIANG
Basic & Clinical Medicine 2006;0(01):-
Objective To investigate the prevalence of hyperuricemia and its associated factors including dietary and Metabolic Syndrome in populations of Dongcheng district in Beijing.Methods A cross-section study of hyperuricemia was carried out in volunteers who had diabetes screening from 2003 to 2004.The prevalence of hyperuricemia was calculated in the population.Applying the form of food frequency to know the intake of nutrition-rich dietary.Results The prevalence of hyperuricemia in this population was 4.3%.In male and female were 10.7% and 1.07% respectively.Bivariate and rank analysis found that hypertriglyceride were associated with increased prevalence of hyperuricemia(P
10.Effects of Small Volume Resuscitation with Different Fluids on Lung of Rats Undergoing Endotoxic Shock
Jianqi WEI ; Jianqiang GUAN ; Gaofeng YU ; Ziqing HEI ; Jun CAI ; Jinghui CHEN
Journal of Sun Yat-sen University(Medical Sciences) 2010;31(2):238-241,248
[Objective]This study was designed to investigate the effects of small volume resuscitation with different fluids on the lung of endotoxie rats.[Methods]Thirty SD rats weighting 180-250 g were divided randomly into 5 groups(n=6):Group C[lipopolysaccharide(LPS)negative control group],Group E(LPS+4 mL/kg physiologic saline),Group HSS(LPS+4 mL/kg 75 g/L hypertonic saline solution),Group HES(LPS+4 mL/kg hydroxyethyl starch 130/0.4),Group HSH(LPS+4 mL/kg 75 g/L hypertonic sodium chloride hydroxyethyl starch 40).Resuscitation was administrated 30 min after LPS injected.Pathological examination and score were made under optical microscope.Dry/wet ratios were observed.Levels of total protein of bronchoalveolar lavage fluid(BALF)were measured.Thibabituric acid(TBA)was used to measure tissue malonaldehyde(MDA)levels.Xanthine oxidase(XO)was employed to measure the tissue activity of superoxide dismutase(SOD).[Results]Compared with group C,in the other 4 groups,pathological changes were server.Levels of total protein of BALF were higher(P<0.05).Pathological score of group E was significantly higher(P<0.01).Dry/wet ratio of group E was lower(P<0.05).Tissue activity of SOD of group E was lower(P<0.01).Levels of tissue MDA in group E and HSS were significantly higher.Compared with group E,in group HSS,HES and HSH,pathological changes were slighter(P<0.01).Pathological scores and tissue MDA levels were lower(P<0.01).Dry/wet ratios were higher(P<0.05).Tissue activity of SOD were higher(P<0.01),levels of total protein of BALF were lower(P<0.05,P<0.01).[Conclusion]Small volume resuscitation with HSS,HES,and HSH had protective effects on the lung of endotoxie rats.HES and HSH had better effect on decreasing the capillary permeability of the lung of endotoxic rats lung compared with HSS.