AIM To establish a new animal model of gastric cancer with high incidence rate and short experimental period. METHODS Using N methyl N′ nitro N nitrasoguanidine(MNNG) combining ucler to induce rats to gastric cancer, taking the pathological situation of rats as the standard of canceration. RESULTS Six rats coming from model group were found as gastric cacinoma, the incidence rate of gastric cancer can reach forty percent. CONCLUSION This method can induce high incidence rate of gastric cancer during short experimental period. It deserves imroving and developing.

AIM　To establish a new animal model of gastric cancer with high incidence rate and short experimental period. METHODS　Using N-methyl-N′-nitro-N-nitrasoguanidine(MNNG) combining ucler to induce rats to gastric cancer, taking the pathological situation of rats as the standard of canceration. RESULTS　Six rats coming from model group were found as gastric cacinoma, the incidence rate of gastric cancer can reach forty percent. CONCLUSION　This method can induce high incidence rate of gastric cancer during short experimental period. It deserves imroving and developing.