1.Analysis of citation rate of scientific papers published in Medical Journal of Chinese People's Liberation Army
Medical Journal of Chinese People's Liberation Army 2001;0(08):-
Objective To evaluate the academic level and the popularity of Medical Journal of Chinese People's Liberation Army. Method According to the information of Chinese Medical Citation Index(CMCI), The amount and distribution of the original in Medical Journal of Chinese People's Liberation Army cited by the journal included by CMCI were analyzed. Result The citation rate of published articles was 36.54%, and the average of original articles cited by other researchers was 2.70. The distribution of the most frequently cited authors covered 24 provinces, with Beijing, Shanghai and Guangdong Province in the lead in research work relevant to military medicine. The published papers were cited by 451 journals, and self-citing rate was 0.20. Conclusion Original medical scientific articles of high quality have been published in the Medical Journal of Chinese People′s Liberation Army. It have become one of the most important information resource for the medical researchers in the army and one of the important medical journal in the country.
2.Efficacy of structured triglycerides in parenteral nutrition in elderly patients with acute biliary tract infection
Zhe LI ; Jinghai SONG ; Bin HUA ; Yong LAN ; Junmin WEI
Chinese Journal of Geriatrics 2015;34(2):165-167
Objective To investigate the safety and efficacy of structured triglycerides in parenteral nutrition in elderly patients with acute biliary tract infection.Methods 62 elderly patients with acute biliary tract infection under conservative therapy were randomly divided into structured triglycerides (ST) group and medium-chain triglycerides plus long-chain triglycerides (MCT/LCT) group.Patients underwent parenteral nutrition for 5 days.Levels of hepatic enzymes,blood triglycerides,nitrogen balance,fasting blood insulin and glucose were compared between the two groups after 5 days of parenteral nutrition.Results There were no significant differences in levels of hepatic enzymes,blood triglycerides and fasting blood glucose between ST group and MCT/LCT group.Plasma total bilirubin (T-Bill) levels were increased in the two groups,and T-Bill level dropped faster in the ST group than in the MCT/LCT group after 7 days of parenteral nutrition(P< 0.05).The difference in total cholesterol level dropping was significant between ST group and MCT/ LCT group (P<0.05).The cumulative nitrogen balance for 5 days had significant difference between ST and MCT/LCT groups [(4.7-±-2.2) g vs.(2.8±0.7) g,P<0.05].STG group versus MCT/LCT group had less fluctuation of fasting blood insulin level after 1,4 and 7 days of parenteral nutrition.Conclusions In the acute phase of biliary tract infection in elderly patients,ST-based parenteral nutrition can provide energy and help maintain nitrogen balance,with a little fluctuation of fasting blood insulin level.Short-term nutritional support may have better tolerance in the liver and has little effect on the change of hepatic enzymes.
3.A retrospective analysis of clinical characteristics and outcomes of heart failure patients with different left ventricular ejection fractions
Haobin ZHOU ; Dongqi AN ; Qiong ZHAN ; Zuheng LIU ; Jinghai HUA ; Wenyan LAI ; Yuli HUANG ; Qingchun ZENG ; Dingli XU
Chinese Journal of Internal Medicine 2017;56(4):253-257
Objective To compare the clinical characteristics,and outcomes of patients with heart failure with different left ventricular ejection fractions (LVEF).Methods A total of 1 182 hospitalized patients with heart failure (HF) were enrolled and retrospectively studied in the present study.The patients were stratified by LVEF as reduced (HFrEF,LVEF < 40%,n =313),mid-range (HFmrEF,40% ≤ LVEF <50%,n =287) and preserved (HFpEF,LVEF≥50%,n =582) ejection fraction groups.Among the 1 182 cases,941 of them (81.3%,84.9%,and 84.0% inHFrEF,HFmrEF and HFpEF groups,respectively) were followed up for an median duration of 27.3 months.Results (1) Among the study patients,26.5% were in HFrEF,24.3% in HFmrEF,and 49.2% in HFpEF groups.(2) Ischemic heart disease with HFmrEF was more frequent than that in patients with HFrEF.The average age,percentage of female subjects,systolic blood pressure,uric acid,N terminal B-type natriuretic peptide precursor (NT-proBNP),hemoglobin,and the incidence of hypertensive heart disease,anemia,atrial fibrillation in patients with HFmrEF were higher than those in patients with HFrEF,but lower than those in patients with HFpEF (all P <0.01).(3) The all-cause cumulative mortality was 10.8% at 1 year,20.6% at 2 years and 35.9% at 5 years.No difference was observed in the all-cause cumulative mortality at 1 year,2 years,5 years among the three groups (all P > 0.05).Conclusions The HFmrEF patients,as a new and distinct group,were with many intermediate characteristics compared with HFrEF and HFpEF subjects.However,the all-cause mortality was not significantly differeut among HF patients with different LVEF.
4.Alterated Serum Levels of Immunoglobulin E in Patients With Calcific Aortic Valve Disease
Yunyi ZHENG ; Qingchun ZENG ; Qiong ZHAN ; Dingji ZHU ; Jinghai HUA ; Haobin ZHOU ; Dongqi AN ; Zuheng LIU ; Wenyan LAI ; Dingli XU
Chinese Circulation Journal 2016;31(3):263-266
Objective: To explore the relationship between serum levels of immunoglobulin E (IgE) and calciifc aortic valve disease (CAVD) in relevant patients.
Methods: A total of 394 patients were enrolled in our study. Based on echocardiography presentation, the patients were divided into 2 groups: CAVD group,n=169 and Non-CAVD group,n=225. Serum levels of IgE were examined by chemiluminescence method. The IgE levels were compared between 2 groups and the relationship between serum IgE level and CAVD was analyzed.
Results: Serum levels of IgE in CAVD group was significantly higher than Non-CAVD group 113.30 IU/ml vs 63.76 IU/ml (P<0.05); multivariate logistic regression analysis conifrmed above difference (P<0.05) and it also indicated that the alteration of surum IgE level is obviously related to CAVD occurrence.
Conclusion: Serum IgE level is obviously increased in CAVD patients. IgE is an independent biochemical indicator of CAVD, it may play the important role in CAVD pathogenesis.
5.Influencing factors analysis of microvascular invasion in patients with hepatocellular carcinoma
Peiyuan DU ; Jinghai SONG ; Jiangchun QIAO ; Xiuwen HE ; Jinsong ZHANG ; Jian CHEN ; Hua LYU ; Mingwei ZHU ; Junmin WEI
Chinese Journal of Hepatobiliary Surgery 2019;25(1):26-29
Objective To evaluate the correlation between microvascular invasion(MVI) and prognosis in patients with hepatocellular carcinoma (HCC),and to analyse the influencing factors of MVI in patients with HCC.Methods Total of 81 patients with hepatocellular carcinoma treated in Beijing Hospital from January 2014 to December 2016 were retrospectively studied.There were 65 males and 16 females.The mean age was 59.6± 12.7 years,and the age ranged from 21 to 87 years old.Pathological examination showed presence of MVI in 35 patients.Results Total of seventy-six patients with hepatocellular carcinoma were followed-up.The 1-,2-,3-and 4-year overall survival rates in the 35 patients with microvascular invasion of hepatocellular carcinoma were 78.6%,55.4%,38.3%,and 32.2%,respectively.The 1-,2-,3-,and 4-year overall survival rates of the 41 patients without microvascular invasion were 93.4%,76.5%,68.2% and 68.2%,respectively.The difference was significant (P<0.05).Cox multivariate regression analysis showed that microvascular invasion was an independent risk factor of overall survival after surgery (HR=3.071,95% CI:1.239~7.610,P<0.05).Sub-group analysis was done on patients with microvascular invasion based on pathological results which included the number of MVI lesions,the call number in the MVI lesion,the distance of the MVI to the primary liver cancer,and the gradings of MVI.There were no significant differences in the overall survival outcomes (P>0.05).Multivariate logistic regression analysis showed the maximum diameter of tumor > 5 cm (OR =6.340,95% CI:2.000 ~ 20.096),preoperative total bilirubin (TBil) > 17 μmol/L (OR =5.067,95%CI:1.386 ~ 18.525),and preoperative alpha-fetoprotein (AFP) >400 μg/L (OR =6.042,95% CI:1.435 ~ 25.444) were independent risk factors of microvascular invasion (P< 0.05).Conclusion Hepatocellular carcinoma patients with microvascular invasion had poor prognosis.Preoperative AFP,preoperative TBil,and diameter of tumor were independent risk factors of microvascular invasion in patients with hepatocellular carcinoma.