1.Xuebijing injection combined with oral acitretin for the treatment of 24 cases of erythrodermic psoriasis
Zhiming TANG ; Mengqing JING ; Xiaoxiang ZHAI ; Cuixia ZHANG ; Jingguo LI
Chinese Journal of Dermatology 2013;(3):185-186
Objective To evaluate the efficacy of Xuebijing injection plus oral acitretin for the treatment of erythrodermic psoriasis.Methods Forty-eight patients with erythrodermic psoriasis were equally and randomly divided into two groups by a random number table:test group treated with Xuebijing injection once a day plus oral acitretin,and control group treated with oral acitretin.The dose of acitretin began at 0.5 mg per kilogram per day,and was modified according to the tolerance in and response of patients.After 8 weeks of treatment,clinical efficacy was evaluated by psoriasis area and severity index (PASI) score,response rate and recurrence rate.Adverse reactions were also recorded and evaluated.Results The difference in PASI score between pre-and post-treatment was significantly higher in the test group than in the control group (34.9 ± 2.2 vs.27.3 ± 1.7,t =3.37,P < 0.05).The total response rate was 87.5% in the test group and 62.5% in the control group (x2 =4.87,P < 0.05).There was a statistical decrease in the average onset time ((13.5 ± 2.4) d vs.(20.7 ± 3.1) d,t =3.67,P < 0.05),daily dose and total dose of acitretin ((26.4 ± 3.3) mg vs.(34.7 ± 3.5) mg,(1854.5 ± 85.2) mg vs.(2768.8 ± 88.7) mg,t =3.07,4.32,respectively,both P < 0.05) in the test group compared with the control group.The recurrence rate was 9.5% (2/21) in the test group and 26.6% (4/15) in the control group (x2 =5.23,P < 0.05).Conclusion In the case of erythroderma psoriaticum,Xuebijing injection combined with oral acitretin is superior to oral acitretin alone in clinical efficacy,onset time and reducing recurrence.
2.Postpartum family visits to parturients in communities
Meiling HUANG ; Jingguo ZHAI ; Taizhen LUO ; Yun CHEN
Modern Clinical Nursing 2013;(8):19-21
Objective To investigate postpartum family visits to the parturients in communities.Method Eighty six post-natal parturient women took part in the investigation by using a self-designed questionnaire.Results 57.0%of them received one postpartum visit and the visit time ranged between 15~30 min.72.1%of visits were about check of the wounds and lochia;23.3%of visitors were from milk companies.74.4%of mothers thought that the visitors lacked of professional knowledge.47.7%of them thought the visits lacked of professional content.24.4%of them thought that the visits were not in time.Conclusion Enriching the knowledge of postpartum care,updating visitors' knowledge,enriching the contents of health care and standardizing visit management are of importance for the increase of visits.
3.Expert consensus on the rational use of psychotropic drugs related to intensive care medicine
Shenglin SHE ; Zhen SONG ; Tongwen SUN ; Jingguo ZHAI ; Yan YU ; Ningbo YANG ; Maosheng FANG ; Wenbin GUO ; Man WANG ; Guanglei XUN ; Lulu ZHANG ; Xijia XU ; Xiaoli WU ; Qinling WEI ; Fang LIU ; Huiping LI ; Xingrong SONG ; Youping WANG ; Yingjun ZHENG ; Xueqin SONG
Chinese Journal of Nervous and Mental Diseases 2024;50(9):513-524
Critical care medicine-related treatment is an interdisciplinary and multi-professional process,often leading to secondary or concomitant mental disorders in clinical practice.Currently,there is no consensus on the pharmacological treatment of related mental illnesses in China.The Chinese Society of Psychosomatic Medicine collaborated with the Critical Care Medicine expert group to form a consensus writing expert group.After a systematic review of relevant literature,summarizing published domestic and foreign literature,and extensive discussions,the consensus was developed.The consensus elaborates on the principles and processes of the standardized use of psychotropic drugs in critical care medicine,as well as the clinical indications,precautions,and specific drug selection of various psychiatric medications,providing feasible suggestions and guidance for the clinical application of psychiatric medications in the intensive care unit.