Diabetic peripheral neuropathy is one of the three main complications of diabetes. Its morbidity is up to 90%. Recent years, using Chinese medicine treating this disease is very popular in China, especially using activating blood to resolve stagnation to solve this problem. The author reviewed the progress of studies on treatment of diabetic peripheral neuropathy by activating blood to resolve stagnation, and put forward the future research direction.

Real-time three-dimensional echocardiography(RT-3DE) has been validated for its accurate diagnoses and quantitave mearsurement of mitral valve disease,which could act as a guide in selecting the proper therapeutic strategy for each individual in clinical setting.In this article,the recent research achievements on RT-3DE in mitral valve disease were summarized,and the application of RT-3DE in surgical approach to mitral valve disease was discussed as well.

Objective:To investigate the effect of sonodynamic therapy with hematoporphrin on the expression of VEGF in Chick Chorioallantoic Membrane and provide experimental basis for appling sonodynamic therapy(SDT)on anti-angiogenesis in tumor therapy.Methods:The hatching eggs cultured for 7 days were randomly divided into 4 groups:blank control group,ultrasound group,hematoporphrin group,sonodynamic therapy group.The express of VEGF in CAM was detected by immunity histochemistry.Result:There were significant differences between control group and ultrasound group(P0.05),conclusion The results show that sonodynamic therapy with hematoporphrin has a significant inhibitionary effect on the express of VEGF in CAM and this maybe is the most important mechanism of its anti-angiogenesis effect.

Objective:This study explores Achenbach's three famous checklists regarding to children's behavior problems:CBCL,YSR,TRF.The checklists are translated into Chinese and tested for their relativity and applicability.Methods:1410 adolescents selected from 6 middle schools in Beijing are investigated with CBCL,YSR and TRF.Results:The Cronbach ? among the items of the three checklists and the total score are 0.96,0.95,and 0.99 respectively,the split-half reliability are 0.93,0.89,and 0.97 respectively,which demonstrates an obvious homogeneity within the three checklists.Scores in YSR are generally higher than those of the other two checklists, scores in CBCL follow immediately,and scores in TRF are the lowest(except for a minority of individual factors). The scores in CBCL and YSR are significant correlated(r=0.35～0.60,P

OBJECTIVE:To evaluate the rationality of drug use in cancer patients in Tiantan Hospice Hospital.METHODS:By a retrospective study,the drug use in cancer patients in Tiantan Hospice Hospital who died during Jan.2008 and Sep.2008 were analyzed statistically.RESULTS & CONCLUSION:The drug use in cancer patients in Tiantan Hospice Hospital was rational on the whole.Step medication,oral medication,on time medication and individual medication were realized in Beijing Tiantan Hospice hospital and treatment on cancer patients in this hospital was in line with the Guideline for Cancer Pain Management Based on the Three-step Analgesic Ladder recommended by WHO.

Objective To investigate the causes and characteristic of placental abruption.Methods Clincal data of 52 patients with placental abruption were retrospectively analyzed.Results Compared with other incentives,gestational hypertension disease(especially in the severe group)had a significant difference (P ＜ 0.05),but in this group of materials due to placental premature rupture caused by placental abruption are light;on two groups of children to mode of delivery were compared,the difference was statistically significant (P ＜ 0.05) ;on two groups of maternal postpartum were compared,the difference was statistically significant (P ＜ 0.05) ; the two group of fetuses were compared,the difference was statistically significant(P ＜ 0.05).On 7 cases of fetal asphyxia of active treatment were cured.Conclusion In order to further reduce the incidence of placental abruption should the knowledge of this disease is caused take seriously,strengthen to the prevention of the disease as well as publicity and education,and further improve the prenatal diagnosis and treatment level,as the child 's life to provide security protection.

ObjectiveTo compare the clinical efficacy and side effects of liver damage of the methylprednisolone (methylprednisolone tablets ) and prednisone treating nephrotic syndrome compicated with hepatitis B.Methods66 patients with nephrotic syndrome complicated with hepatitis B were randomly divided into control group and observation group,and each group had 33 cases.The control group was given prednisone in the morning,while the observation group was received methylprednisolone.The clinical efficacy and side effects of liver damage were compared between the two groups.ResultsAfter the treatment,the biochemical index significantly improved compared with the pre-treatment( all P ＜ 0.05 ) ;The total effective rate of observation group was 93.94％ higher than 84.85％ of the control group( x2 =1.44,P ＞ 0.05 ).However,there was no significant difference between the two groups( P ＞0.05) ;The observation group was significantly higher than the control group in negative rate of HBV-DNA (x2 =4.69,P ＜ 0.05 ) ;The side effects of liver damage in the observation group were lower than the control group (t =5.62,5.13,P ＜ 0.05 ).ConclusionMethylprednisolone and prednisone for treating patients with nephrotic syndrome compicated with hepatitis B had good clinical efficacy,and methylprednisolone was more effective than prednisone,especially it had less side effects of liver damage than prednisone.

Age-related macular degeneration (AMD) can cause irreversible severe visual impairment.At present,a large number of basic and clinical research has documented several effective treatment for wet AMD.As for dry AMD,so far there is no effective therapy and preventive measure.Dry AMD probably worse for macular choroidal neovascularization (CNV) or geographic atrophy (GA) to its later stage,resulting in severe visual impairment.In recent years,some promising treatment strategies are emerging,mainly in the prevention of the damage of photoreceptor and retinal pigment epithelium,such as drug therapy,laser photocoagulation,surgery,plasma exchange,stem cell transplantation and gene therapy.These therapies are expected to be able to bring hope for arresting the development of dry AMD.This article reviews the current researches and possible future management of dry AMD.

Age-related macular degeneration (AMD) is the leading cause of the irreversible vision loss in population over 55 years of age.With the increasingly serious problem of aging,the prevalence of AMD is rising year by year.However,as the pathogenesis of dry AMD is largely unknown,the effective therapy still is lack.Given that there was a lack of proper animal models,it brought about obstacles to researches about molecular mechanism underlying dry AMD.Nowadays,lots of murine models of dry AMD have been established and developed,which provide suitable tools for relevant researches.But,different dry AM D models show varied pathogenesis features,and a reasonable choice of models is very important for different studies.The characteristics of different dry models were reviewed in this article.

Collaborative inquiry applied in teaching of literature retrieval course is beneficial for the unity and cooperation between teachers and students,and their independent study ability. Described in this paper is the collabo-rative inquiry in teaching of information retrieval course with its target, methods and program carefully designed for medical postgraduates according to the students-oriented construction theory, which can promote the growth up of teachers and students, and learn the frontier and innovative theories, and practical knowledge.