Objective To study the immune state and correlated strategy of patients with hepatic cirrhosis and primary hepatic carcinoma.Methods 17 patients with hepatic cirrhosis and 8 patients with primary hepatic carcinoma(PHC) in our hospital were collected since 2002.The indexcs of immune function were detected in all patients and some were re-examined.Results It was found that although the immune index varied in patients suffering from severe liver diseases,some regularities were shown as follows:(1)CD4 and CD4/CD8 in T lymphocyte subset declined markedly(P

Though prokaryotic cells could hardly express recombinant human beta nerve growth factor (rhNGF-?) with a proper three-dimensional conformation, using of E. coli as a host for industrial production of rhNGF-? is controversial. Recombinant human beta NGF was expressed in E. coli and was refolded in vitro. The isolated products was shown to be consistent with those expressed and secreted by CHO cells in biochemical characters by SDS-PAGE, RP-HPLC, mass spectrometry, N terminal analysis and bioassay determined using DRG and PC12 cells. The products can be acquired with 95% purity, 1.8 ng/U biological activity from both expression system,which remain invariable biological activity when lyophilized in excipient and store at 37℃?2℃, RH 75%?5% for 3 months. Moreover, the product refolded from inclusion bodies of E. coli shows the predominance in homogeneity and the lower cost.

Objective: To summarize our experience on perioperative anesthesia management of patients with crush syndrome caused by earthquake under field condition. Methods: The clinical anesthesia data of 10 patients with crush syndrome caused by China Wenchuan earthquake, who were treated under field condition, were retrospectively analyzed, and our experience on perioperative anesthesia management was summarized. Results: After volume therapy, urine alkalization, and stabilization of internal environment, the 10 patients underwent debridement, decompression by fasciotomy or amputation under epidural anesthesia or brachial plexus block plus psychological therapy and moderate tranquillizer. During the operation, the patients showed smooth respiratory and cardiovascular characteristics without pain. Conclusion: Under field condition, regional anesthesia can provide adequate analgesic effect during and after the surgery. Early fluid resuscitation and life support are vital to the safety and life of patients.

Acupuncture Therapy ; Adult ; Female ; Humans ; Psoriasis ; therapy

Aged, 80 and over ; Female ; Fracture Fixation ; adverse effects ; Humans ; Male ; Postoperative Complications ; etiology ; Radius Fractures ; surgery

The development and progress of gastric mucosal diseases is a complex process associated with multiple factors and underlying mechanisms,and individuals may present different genetic susceptibilities to gastric mucosal diseases. Various studies have demonstrated a strong link between Toll-like receptors( TLRs),as pattern recognition receptors,and the development and progress of gastric mucosal diseases. The gene polymorphisms of TLRs may change its encoded proteins or related signaling pathways,which results in different susceptibilities to gastric mucosal diseases;this might affect the development,progress and clinical outcome of the disease. In this review article,the advances in study on TLRs and its gene polymorphisms in gastric mucosal diseases were summarized.

Alzheimer's disease (AD) is the most common form of dementia, which affects more than 35 million people worldwide with increasing tendency. AD brings stupendous economic burden for both the society and family. It has become a major global public health issue. Electro-acupuncture (EA) therapy has been widely used in AD treatment with satisfactory results. Based on the basic research, this paper explored the therapeutic effect of EA in AD treatment from the learning ability and morphological changes in AD animal models. From the cholinergic neuronal apoptosis theory, inflammatory response theory, oxidative stress theory and other aspects, the action mechanism of EA in the treatment of AD animal models were reviewed. At last, limitations of EA in AD treatment were analyzed. It proposed the outlook of a new type of EA-music EA in AD treatment. It provided a new idea and method for AD clinical treatment.

Objective To discuss the application value of multi- position radiography in the diagnosis for fracture of rib.Methods 98 cases with integrated data of thoracic trauma undergone multi- position view X-ray from 2007 to 2009 were retrospectively reviewed.Results The percent of fractures with orthophoria view is 65.4%.The percents of fractures with oblique position,tangential projection and spot film under the X-ray fluoroscopy are 20.6%、5.1% 、8.8%,while doesn' t find the A-P position,The total percent is 34.6%.Conclusion Multi-position radiography can elevate the diagnosis for fracture of rib and has application value.

Objective:To observe the efficacy of Chuankezhi injection combined with budesonide and formoterol fumarate powder for inhalation in the treatment of chronic obstructive pulmonary disease ( COPD) . Methods:Totally 120 patients with COPD were ran-domly divided into two groups:the observation group inhaled budesonide and formoterol fumarate powder for inhalation combined with intramuscular injection of Chuankezhi injection, and the control group inhaled budesonide and formoterol fumarate powder for inhala-tion. The treatment course was 28 days. The pulmonary function indices [ FEV1% expected value, FEV1 /FVC, 6 min walking dis-tance (6MWD)], the times of acute exacerbation and the adverse drug reactions during the treatment were observed and compared be-tween the two groups. Results:After the treatment, the lung function and 6MWD were improved in the two groups, and the improve-ment of FEV1% expected value in the treatment group was more obvious than that in the control group [(59. 7+12. 1)% vs (49. 8+11. 3)%, P<0. 05]. The number of patients with at least once of acute exacerbation was significantly reduced in the treatment group when compared with that in the control group (35% vs 62%, P<0. 01). The incidence of adverse drug reactions in the two groups showed no significant difference. Conclusion:Chuankezhi injection combined with budesonide and formoterol fumarate powder for in-halation can notably improve the lung function in the patients with COPD and reduce the times of acute exacerbation without effect on the incidence of adverse drug reactions.

Objective To analyze the genetic diversity of snail populations from five provinces in China mainland. Methods Genomic DNA was amplified by random primer and the products were electrophoresed by 8% polyacrylamide and stained by 0.6% silver nitrogen. The results were recorded and analyzed. Results The average similarity and match percentage among the nine snail populations were 0. 721 4 and 0. 680 9 respectively. The cluster trees showed that the nine snail populations could be divided into three groups ; snails from Dali of Yunnan Province and Puge of Sichuan Province were the first isolated group; snails from Fuqing of Fujian Province and Dongtai of Jiangsu Province were clustered into the second group; the other four populations from Anhui Province and snails from Yixing of Jiangsu Province belong to the last group. Conclusion There is a large diversity among smooth-shelled snails in China although close relationship exists. The cluster trees gained by different snail populations are basically the same and consistent with the distribution of these populations. However, further study should be carried out on the cluster of smooth-shelled snails from Dongtai of Jiangsu Province.