Lens opacity attenuates the contrast sensitivity and clarity of eye due to scattering of light,which leads to poor vision in cataract patients.Phacoemulsification with primary intraocular lens is the primary surgical approach.Some complaints of vision discomfort commonly occur although the vision acuity is good.It is,therefore,vital for us to seek an objective evaluation system of visual quality after cataract surgery.Contrast sensitivity test and visual questionnaire offer valuable input for this issue.Contrast sensitivity can estimate vision function more accurately to better measure visual impairment preoperatively and vision outcome after cataract extraction.

0.05).Comparison group model and normal control:detected the numbers of endothelial cells:①1 month:control group contrast with test group has no changed;②3 month:group 30Gy/N(P

Objective To explore the incidence of facial hormone-dependent dermatitis, and to raise the healing rate of it. Methods We applied non-steroid drug topically, cold compress combined with anti-histamine agents to treat facial hormone-dependent dermatitis in 68 cases. The results were compared before and after the treatment. Results There were significantly clinical effects of non-steroid drug topically, cold compress combined with antihistamine agents on facial hormone-dependent dermatitis, with healing rate of 82. 4 % , and effective rate of 100 %. Conclusions In order to reduce the incidence of facial hormone-dependent dermatitis, we should follow the principal of applying steroid agent strictly to treat facial dermatitis. Meanwhile, there is significantly clinical effects of non-steroid drug with topical use and cold compress combined with antihistamine agents on facial steroid-dependent dermatitis.

OBJECTIVE:To study the general regularity and characteristics of adverse drug reaction caused by meropenem,and to provide reference for rational use of drugs.METHODS:Vesicle and bullous change occurring in one patient with allergic dermatitis,age of 80,treated with meropenem were analyzed.Literatures about meropenem-induced ADR reported in domestic pharmaceutical journals from Jan.1994 to Dec.2009 were collected and analyzed statistically.RESULTS:Meropenem rarely caused ADR.The most clinical manifestations were diarrhea,rash and abnormality of liver function.CONCLUSION:Meropenem-induced ADR case is rare as well as allergic dermatitis.Great importance should be attached to meropenem-induced ADR.

10.3969/j.issn.2095-4344.2013.23.025

Objective To investigate the therapeutic effects of the losartan combined with atorvastatin on patients with diabetic nephropathy (DN).Methods 122 patients with DN were randomly divided into two groups,61 cases in the control group were received conventional therapy and added the losartan,61 cases in the observation group were treated by atorvastatin on the basis of the control group.The treatment time was 12weeks for each group.After 12 weeks,the systolic blood pressure (SBP),diastolic blood pressure (DBP),triglycerides (TG),total cholesterol (TC),low-density lipoprotein cholesterol (LDL-C),high density lipoprotein cholesterol (HDL-C),fasting blood glucose (FBG),urinary albumin excretion rate (UAER),serum creatinine (Scr),and glycosylated hemoglobin (HbAIc) were measured.Results The total effective rate was 93.44％ in the observation group,and 75.41％ in the control group,with a statistically significant difference between two groups (x2 =7.54,P ＜ 0.01).After 12 weeks,the SBP and DBP were all changed more than before,DBP decreased more significantly (SBP:t =16.25,17.34,P ＜0.01 ;DBP:t =18.10,17.04,P ＜0.01); FBG,UAER,and HbAlc in the control group were significantly reduced (P ＜ 0.05) ; the TG,TC,LDL,-C HDL,-CFBG,UAER,Scr,and HbAlc of the observed group were significantly reduced more,too.TG,TC,UAER,and Scr of the observed group were significantly lower than the control group (P ＜ 0.05).Conclusions The losartan combined with atorvastatin that were used to treat patients with DN can reduce the urine albumin and protect the renal function.

The techniques of diagnose and treatment of Gastrointestinal Endoscopy have played very important roles in digestive diseases at present. The level of teaching quality of gas- trointestinal endoscopy can be improved through practice of clinical teaching of normalization endoscopy training. Research students can master some common techniques of diagnose and treatment of gastrointestinal endoscopy,and lay a good foundation for their future work.

OBJECTIVE: To improve the management level in outpatient dispensary.METHODS: The current management model in each outpatient dispensary of our hospital was introduced;the problems were pointed out and the proposals were put forward.RESULTS & CONCLUSIONS: The current outpatient pharmacy management mode and drug control measures of "individual responsibility,weekly small stocktaking,monthly big stocktaking,and irregular spot checks" is feasible,if optimized further,which would help enhance the working quality and service level in pharmacy.

H~3-thymidine was used in determining the neuronal mitosis of the traumati cerebral cortex in rats. Intraperitoneal injection of H~3-thymidine was given to the rats immediately after corticectomy of the parietal lobes. On the 4th day after operation, the cerebral tissue was removed, fixed in Carnoy, serial sectioned, and stained with cresyl violet.The results showed that in the surrounding area 100—200?m from the traumatic site, 2-5％ of the various types of cells in the cerebral tissue were labeled, i. e. silver granules were distributed within the nuclei. Macrophages, endothelial cells and pericytes of vessels make up most of the 2—5％, whereas neuroglia and neuron rank next. The nuclei of the majority of the labeled cells were in the interphase state and a few of them were in the mitotic state. The more the labeled cells are in the interphase state,, the more the mitosis occur. On the contrary, it is less. They are always in direct proportion. In the case of neurons the same situation occurs.By inference, the mitotic division of the neurons in the cerebral cortex may occur in situ. Possibly some kind of substance is produced after the trauma leads to the division of the mature neurons. The basis for this inference is that a certain number of the neurons in division have typical features of the pyramidal neurons.

Since the first launching of heart lung bypass machine in animal model in 1937,cardiopulmonary bypass(CPB) has become more and more consummate,but it still brings about many complications,including pulmonary,renal and hepatic dysfunctions.Among these complications,hepatic dysfunction plays an important role in the impairment after cardiac operations.The liver function indices such as aspartate aminotransferase,glutamate-pyruvate transaminase,bilirubin and alkaline phosphatase will step up obviously during 3 to 5 days after the operation.The physiological changes deteriorate patient's condition,and even influence the prognosis.This clinical phenomenon puzzles cardiac surgeons.All these demand us to answer the following questions: Is the cardiopulmonary bypass harm the liver? What's the mechanism? We review the different researches on hepatic injury after cardiopulmonary bypass.