1.The Relationship between Behavior Types and Plasminogen Activation System in Patients with Coronary Heart Disease
Jinfu ZHU ; Desen YANG ; Shuiyuan XIAO
Chinese Mental Health Journal 1991;0(04):-
Objectives: To study the difference of Plasminogen Activation System in patients with coronary heart disease by different behavior types. Methods: 81 patients with coronary heart disease and 59 normal control were evaluated by Type A Behavior Scale. t-PA and PAI-1 activities of both groups were also measured. Results: The activity of PAI-1 was higher and t-PA was lower in patients with coronary heart disease, and this difference is also found between Type A and Non Type A patients. Conclusion: The activity of t-PA is decreased and PAI-1 increased in patients with CHD, this phenomenon are also related to Type A Behavior traits.
2.Osteoporosis and nitric oxide
Ang LI ; Jinfu XIAO ; Ya XUE
Chinese Journal of Pathophysiology 1986;0(02):-
Recent work has shown that nitric oxide (NO) induction by nitric oxide synthase(NOS) is the physiological mediator of bone cell function and demonstrated that it may be possible to exert differential effects on osteoblast (OB) and osteoclast (OC) activity in vivo. The proinflammatory cytokines, such as tumor necrosis factor-? (TNF-?), interleukin-1? (IL-1?), interferon-? (IFN-?), will stimulate bone resorption by NOS-induced low levels of NO. These findings confirm NO as a potentially important osteoblast-osteoclast coupling factor, indicating that cytokine-induced NO was largely responsible for the mechanisms of osteoporosis. Pharmacological modulation of NO may therefore represent a new approach in the treatment of bone diseases characterized by increased bone resorption, such as osteoporosis (OP).
3.The Relationship of the Mood and Behavior Types in Patients with Coronary Heart Disease
Jinfu ZHU ; Desen YANG ; Shuiyuan XIAO ; Suixin LIU
Chinese Journal of Clinical Psychology 2001;0(03):-
Objective: To study the relationship of the mood and behavior types in patients with coronary heart disease, to supply the foundation of psychotherapy in patients with coronary heart disease. Methods: 81 patients with coronary heart disease and 59 normal healthy people were evaluated by Type A Behavior Scale, Hospital anxiety and depression scales. To analyse the relationship between the behavior type and mood disorder. Results: The rates of Type A behavior and anxious mood disorder were significantly higher in the study group than the contrast group (P
4.Application of the index system for clinical evaluation of implementation effect: An example of vaginal delivery
Ping MAO ; Chen DENG ; Xiao ZHU ; Aijing LUO ; Siqing DING ; Jinfu YANG
Journal of Central South University(Medical Sciences) 2018;43(1):22-27
Objective:In order to apply the index system for clinical evaluation of implementation effect in hospitals.Methods:A total of 862 patients with vaginal delivery from 9 hospitals were randomly divided into an clinical pathway group (n=496) and a control group (n=366).The patients in the control group received traditional treatment procedure while the patients in the clinical pathway group experienced procedure of the clinical treatment.The index system was used for clinical evaluation of implementation effect.Results:There were obvious advantages in 15 indicators in the clinical pathway group than those in the control group (P<0.05).The comprehensive score of the clinical pathway group was higher than the control group of the corresponding grade and nature of the hospital.The comprehensive score for secondary hospitals (Ci=0.7967) were higher than that for the tertiary hospitals (Ci=0.2033).The comprehensive score for the general hospitals (Ci=0.8948) were higher than that for the specialized hospitals (Ci=0.1052).As for clinical implementation effect,the secondary hospitals were better than the tertiary hospital,and the general hospitals were better than the specialized hospitals.Conclusion:The index system for clinical evaluation could quantify the implementation effect,and compare the implementation effect in different hospitals,which provides reference for the management of clinical pathway.