1.Development of uninterrupted power supply (UPS) of vehicular-charging for portable type-B ultrasonic in battle field
Guoqing ZHANG ; Yongping GUAN ; Guoqing ZHAN ; Jinxia AI ; Jinfeng ZHAO
Chinese Medical Equipment Journal 1989;0(01):-
Objective To introduce a kind of UPS for portable type-B ultrasonic in vehicular-charging at the situation of flowing in battle field. Methods Long time power supply for type-B ultrasonic and other related medical devices was realized through AC/DC alteration switch. Conclusion It functioned well in field test. Conclusion Being light and convenient with AC/DC, it is worth popularizing.
2.Clinical Observation on Prescription of Supplementing Qi and Activating Yang in Treating Sick Sinus Syndrome
Jinfeng LIU ; Yanli WANG ; Liya XU ; Huihui ZHAN ; Ruxiu LIU ; Zhiming LIU
Chinese Journal of Information on Traditional Chinese Medicine 2014;(4):10-12
Objective To observe the clinical therapeutic efficacy of prescription of supplementing qi and activating yang on sick sinus syndrome. Methods According to the random number table, 231 patients with sick sinus syndrome were randomly divided into treatment group and control group. One hundred and fifty patients in the treatment group were given the Chinese herbal medicine while the other 81 patients in the control group were given atropine. The therapeutic course was four weeks in each group. The changes of clinical manifestations and electrocardiogram (24 h Holter monitoring ECG) of two groups were compared. Results The total effectiveness of treatment group was 98.67% (148/150), the control group was 41.98% (34/81), there was a significant difference in the clinical curative efficacy (P<0.01). The total effective rate of the treatment group was 87.3%(131/150) and that of the control group was 35.9%(29/81), and the average increases of heart rates in 24 hours were 9/min and 4/min, respectively. There was significant difference between the two groups (P <0.05). Conclusion The prescription of supplementing qi and activating yang was effective in improving the clinical symptoms and heart rates of patients with sick sinus syndrome.
3.Assessment of the diffusion-weighted imaging for the pathology and renal function in IgA nephropathy
Yan SU ; Liping YANG ; Chong HUANG ; Lianggeng GONG ; Jianhua YIN ; Luo LIAN ; Xiaohua QIN ; Jinfeng ZHAN ; Weiping TU ; Xiangdong FANG
Tianjin Medical Journal 2016;44(7):873-876
Objective To study the correlation between the diffusion-weighted imaging (DWI) measurements and glomerular filtration rate (GFR), Katafuchi scores in IgA nephropathy. Methods Thirty-five patients with IgA nephropathy (IgAN group) and twenty healthy volunteers (control group) were enrolled in this study. All of the subjects underwent bilateral renal DWI measurements with 3.0T MRI scanner. The values of apparent diffusion coefficient (ADC) of renal cortex and medulla were measured. GFR of IgAN group was detected with 99Tcm-DTPA scintigraphy. Based on the Lee classification and the Katafuchi score system, the pathological grading was carried out in patients of IgAN group. The ADC values were compared between control group and different grades of IgAN group. The correlations between ADC and GFR values were analysed in defferent groups. The correlations between ADC values and Katafuchi scores were analysed in IgAN group. Results The renal cortical ADC values were significantly higher than medulla ADC values in both control group and IgAN group (P < 0.05). There were statistically significant differences in renal cortical ADC values and medulla ADC values between control group and IgAN subgroups (P<0.05). But there was no significant difference in renal cortical ADC value between IgANⅠgroup and control group (P>0.05). There was a positive correlation between the renal cortical and medulla ADC values and the GFR values in IgAN group (P<0.01). Negative correlation was found between the renal cortical and
medulla ADC values and the Katafuchi scores in IgAN group (P<0.05). Conclusion The diffusion-weighted imaging can reflect the physiological functions of kidney. It was feasible for application DWI in IgA nephropathy, which can be used for assessing the renal filtration function and the pathological damage. However, DWI measurement is not sensitive to early renal disease.
4.The value of unenhanced computed tomography in differentiating brain tumors from non-neoplastic lesions
Yonghua GUO ; Xiaodong WU ; Jinfeng ZHAN ; Cheng DONG ; Xuejun LIU ; Ruizhi ZHOU ; Song LIU
Chinese Journal of Neurology 2022;55(2):117-124
Objective:To investigate the additional value of unenhanced computed tomography (CT) in the differential diagnosis of brain tumors and non-neoplastic lesions.Methods:A total of 237 cases [140 males and 97 females; (49±16) years old; including 48 cases of low-grade glioma, 134 cases of high-grade glioma, 38 cases of primary central nervous system lymphoma, 9 cases of medulloblastoma, 5 cases of germinoma, and 3 cases of central neurocytoma] of brain tumors (diffuse gliomas and non-glial tumors) diagnosed by biopsy or surgery and pathology in the Affiliated Hospital of Qingdao University from September 2016 to October 2020 were collected retrospectively. Sixty-six cases [46 males and 20 females; (42±13) years old; including 12 cases of abscesses, 5 cases of infarcts, 33 cases of demyelinating lesions, 11 cases of autoimmune encephalitis, and 5 cases of central nervous system vasculitis] of brain non-neoplastic lesions were confirmed by biopsy or clinic. All patients underwent routine magnetic resonance imaging (MRI) scan and unenhanced CT before the treatment. The images were reviewed by two neuroradiologists together blind to the final diagnosis with and without CT images respectively. The diagnostic results and reliability scores were recorded, and the accuracy of the two evaluations was compared.Results:CT hyperattenuation exhibited a higher specificity (95%) than conventional MRI scan (86%), and a lower diagnostic sensitivity (34% vs 86%). Compared to MRI alone, the combined modality of MRI and unenhanced CT significantly improved diagnostic accuracy (94% vs 86%). Additionally, the CT attenuation ratio of non-neoplastic lesions was significantly lower than that of neoplastic lesions [0.69 (0.61,0.78) and 1.14 (1.00,1.25), W=2 123, P<0.05]. The CT attenuation ratio in the non-glial origin tumor group was significantly higher than that in the diffuse glioma group [1.28 (1.18,1.41) and 1.13 (0.97,1.21), W=1 858, P<0.05]. There was no significant difference in grade Ⅲ and Ⅳ groups of diffuse glioma [1.11 (0.99,1.20) vs 1.16 (1.09,1.24), P>0.05 (Nemenyi test)]. However, both were significantly higher than that of grade Ⅱgroup of diffuse glioma [0.89 (0.76,1.07), P<0.05 (Nemenyi test)]. No significant difference was observed between astrocytic tumors and oligodendroglial tumors at the same grade. Conclusions:Hyperattenuation on unenhanced CT is highly specific for the diagnosis of brain tumors. Unenhanced CT plus MRI is more accurate for distinguishing the two entities in hypoattenuation lesion on unenhanced CT.
5.Consistency Experiment of"Ciliao"(BL32)with Auricular Concha on Intragastric Pressure and Heart Rate Variability in Rats Driven by Electroacupuncture
Zheng ZHAN ; Yanhong PAN ; Jinfeng JIANG
World Science and Technology-Modernization of Traditional Chinese Medicine 2023;25(7):2501-2508
Objective To observe the consistency of the effect directions of electroacupuncture(EA)at the"Ciliao"(BL32)and EA on the auricular concha(AC)in regulating intragastric pressure(IGP)and heart rate variability(HRV),and to observe whether the combined EA of"Ciliao"(BL32)and AC has a synergistic effect.Methods SD male rats were divided into EA-AC group,EA-BL32 group and EA-"AC+BL32"group,with 8 rats in each group.And the IGP and HRV were measured before and during EA(30 Hz,2 mA,pluse width 0.2 ms±30%,continuous wave)for 2 min in each group.Results ①Changes in IGP compared with before EA:the IGP in EA-AC group significantly increased especially during the 30th to 60th(P<0.05)and 60th to 90th second of EA(P<0.05);The IGP in EA-BL32 group significantly increased especially during the 60th to 90th second of EA(P<0.05);The IGP in EA-"AC+BL32"group significantly increased especially during the 60th to 90th(P<0.01)and 90th to 120th second of EA(P<0.05).The change rate of IGP of EA-"AC+BL32"group was significantly higher than that of the EA-AC group especially during the 60th to 90th(P<0.01)and 90th to 120th second of EA(P<0.01),and EA-BL32 group especially during the 60th to 90th(P<0.05)and 90th to 120th second of EA(P<0.05).②Changes in HRV compared with before EA:the high frequency(HF)significantly increased(P<0.01,P<0.05,P<0.01,P<0.05),low frequency(LF)significantly increased(P<0.01,P<0.01,P<0.05,P<0.05),and very low frequency(VLF)significantly increased(P<0.05,P<0.05,P<0.05,P<0.05)throughout the EA in EA-AC group;The HF significantly increased(P<0.05,P<0.05,P<0.05,P<0.05),LF significantly increased(P<0.05,P<0.05,P<0.05,P<0.05),and VLF significantly increased(P<0.05,P<0.05,P<0.05,P<0.05)throughout the EA in EA-BL32 group;The HF significantly increased(P<0.05,P<0.05,P<0.05,P<0.05),LF significantly increased(P<0.001,P<0.05,P<0.01,P<0.01),and VLF significantly increased(P<0.05,P<0.01,P<0.05,P<0.05)throughout the EA in EA-"AC+BL32"group.The LF/HF in EA-AC group significantly decreased especially during the 0 to 30th(P<0.01),30th to 60th(P<0.05)and 60th to 90th second of EA(P<0.05);The LF/HF in EA-BL32 group significantly decreased especially during the 0 to 30th second of EA(P<0.05);The LF/HF in EA-"AC+BL32"group significantly decreased especially during the 30th to 60th(P<0.05),60th to 90th(P<0.01)and 90th to 120th second of EA(P<0.01).The change rate of LF/HF of EA-"AC+BL32"group was significantly lower than that of the EA-AC group especially during the 90th to 120th second of EA(P<0.05),and EA-BL32 group especially during the 60th to 90th(P<0.05)and 90th to 120th second of EA(P<0.05).Conclusion The effect direction of EA at"Ciliao"(BL32)and EA on the AC in regulating the vagus nerve is basically the same,and the combined EA of"Ciliao"(BL32)and AC can produce a synergistic effect.
6.Magnetic resonance imaging characteristics of brain lesions in myelin oligodendrocyte glycoprotein antibody associated demyelinating diseases and aquaporin-4 antibody positive neuromyelitis optica spectrum disorders
Jibao WU ; Xiaodong WU ; Jinfeng ZHAN ; Cheng DONG ; Jiufa CUI ; Xuejun LIU ; Ruizhi ZHOU ; Song LIU
Chinese Journal of Neurology 2022;55(7):723-731
Objective:To investigate the distribution and morphological characteristics of brain magnetic resonance imaging (MRI) lesions in patients with myelin oligodendrocyte glycoprotein (MOG) antibody related demyelinating diseases and aquaporin-4 (AQP4) antibody positive neuromyelitis optica spectrum disorders (NMOSD) and their clinical value in early diagnosis.Methods:A total of 35 patients with MOG antibody related demyelinating diseases [20 males and 15 females; aged 31 (25, 43) years] and 36 patients with AQP4 antibody positive NMOSD [3 males and 33 females; aged 42 (29, 54) years] were collected retrospectively from September 2018 to June 2021 in Chenzhou First People′s Hospital and the Affiliated Hospital of Qingdao University which were classified as MOG group and AQP4 positive group respectively. All patients underwent routine cranial MRI scanning before treatment and the location, shape and quantity of intracranial lesions were recorded. Wilcoxon rank sum test was used to compare the number of different types of lesions between the two groups. Logistic regression analysis was used to evaluate the significance of different lesions for the two diseases.Results:There were 7 types of lesions with significant differences in different parts and shapes. Stepwise Logistic regression showed that cortical and juxtacortical lesions ( OR=21.91, 95% CI 3.09-61.69, P<0.05) and infratentorial peripheral white matter lesions ( OR=10.48, 95% CI 2.00-18.89, P<0.05) were the most important risk factors in the MOG group. The incidence of cortical and juxtacortical lesions in the MOG group was 51.4% (18/35), which was higher than that in the AQP4 positive group (2.8%, 1/36; χ2=19.02, P<0.01). The incidence of infratentorial peripheral white matter lesions in the MOG group was 31.4% (11/35), which was higher than that in the AQP4 positive group (5.6%, 2/36; χ2=6.31, P<0.05). Receiver operating characteristic (ROC) curve showed that peripheral lesions [including 6 types of lesions such as supratentorial soft meningitis, cortical encephalitis, cortical and juxtacortical lesions, infratentorial soft meningitis, infratentorial soft meningeal demyelination and infratentorial peripheral lesions, area under curve (AUC)=0.93] were more important than cortical and juxtacortical lesions (AUC=0.75) and central lesions (supratentorial paraventricular white matter lesions, diencephalon, infratentorial paraventricular lesions,AUC=0.64), which had higher diagnostic efficiency. Conclusions:The incidence of intracranial lesions in MOG antibody related demyelinating disease was higher than that in AQP4 positive NMOSD, and the distribution and morphology of intracranial MRI lesions in the two diseases had their characteristic manifestations. Identifying the distribution patterns of peripheral lesions (distributed along pia mater) and central lesions (distributed along ependyma) had a certain reference significance for distinguishing the two groups of diseases.