Objective To study the clinical application value of multi-slice spiral CT iliac venography.Methods The iliac venography with multi-slice spiral CT was performed in 50 cases.150 mgI/ml contrast medium at 2.5～3.0 ml/s was administered via the veins of dorsum of foot and the delayed time was 16～22 s,the images were reconstructed by several methods.The imaging quality and imaging characteristic of iliac vein disease were analyzed.Results Helical CT venography was performed successfully in all patients.Venography showed vein complete occlusion in 31 cases,vessel stenosis or filling defect in 9 cases,normally in 10 cases.The quality of images included:excellent 24%(12/50),good 60%(30/50),bad 16%(8/50),the collectivity was 84%(42/50).Conclusion The multi-slice spiral CT iliac venography is of certain clinical applied value.