1.Value of 3.0 T susceptibility weighted imaging in diagnosis of hemorrhagic diffuse axonal injury
Xiuqin ZHAO ; Yujin DI ; Jinfa XU ; Min BAI ; Chunqing BU ; Shuhua LI
Chinese Journal of Trauma 2012;28(9):790-793
Objective To investigate the value of susceptibility weighted imaging (SWI) in the diagnosis of hemorrhagic diffuse axonal injury (DAI). Methods A retrospective study was conducted on 20 patients with DAI who received MRI examination at day 3 post-injury.MRI sequences included T1WI,T2WI,fluid attenuated inversion recovery ( FLAIR),diffusion weighted imaging (DWI) and SWI.There were 15 patients with the Glasgow Coma Scale (GCS) score≤8,three with GCS score of 9-12 and two with GCS of 13-15.The location and quantity of hemorrhage focus were counted.The area of hemorrhage focus was measured on each MR sequence.Differences of detection rate of hemorrhage focus on each sequence were compared by using X2 test.The correlation between DAI related bleeding area and GCS score was analyzed. Results DAI related hemorrhage focus showed a larger number in superficial cerebrum than that in posterior cranial fossa and in deep cerebrum.The detection rate of hemorrhage focus on SWI was the highest,as compared with other sequences ( P < 0.05 ).Bleeding area and GCS score showed a negative correlation (r =-0.921,P < 0.01 ). Conclusion SWI is very sensitive in detection of the intracerebral hemorrhage focus in the acute period of traumatic DAI.
2.Rapid screening and quality evaluation for the harmful substance 5-hydroxymethyl furfural in commercially available traditional Chinese medicine injection using LC-MS/MS method.
Qingce ZANG ; Jingjing HE ; Jinfa BAI ; Yajie ZHENG ; Ruiping ZHANG ; Tiegang LI ; Zhonghua WANG ; Jiuming HE ; Zeper ABLIZ
Acta Pharmaceutica Sinica 2013;48(11):1705-9
To screen the harmful substance 5-hydroxymethyl furfural content in commercially available traditional Chinese medicine injection which are commonly used, and to preliminarily evaluate the quality of these injections, 5-hydroxymethyl furfural was taken as an index. The contents of 5-hydroxymethyl furfural in 56 samples which consist of 23 kinds of traditional Chinese medicine injections and glucose injection were determined using LC-MS/MS, and 5-hydroxymethyl furfural was detected in 52 of these samples. The minimal content was 0.0038 microg x L(-1) and the maximum content was 1420 microg x mL(-1). The contents of 5-hydroxymethyl furfural were significantly different in traditional Chinese medicine injection which came from different kinds, manufacturers or batches. The results showed the quality difference of commercially available traditional Chinese medicine injection is significant taking 5-hydroxymethyl furfural content as assessment index. More attention should be paid to the safety of 5-hydroxymethyl furfural in traditional Chinese medicine injection, and unified limitation standard should be set to improve medication safety of traditional Chinese medicine injection.
3. Clinical efficacy of laparoscopic stomach intestinal pylorus sparing surgery in the treatment of severe obesity
Lun WANG ; Shixing LI ; Yang YU ; Jinfa WANG ; Yuhui ZHAO ; Lin BAI ; Shu CHEN ; Tao JIANG
Chinese Journal of Digestive Surgery 2019;18(12):1171-1177
Objective:
To investigate the clinical efficacy of laparoscopic stomach intestinal pylorus sparing surgery (SIPS) in the treatment of severe obesity.
Methods:
The retrospective and descriptive study was conducted. The clinical data of 5 patients with severe obesity who were admitted to the China-Japan Union Hospital Affiliated to Jilin University from October to November 2018 were collected. There was 1 male and 4 females, aged from 18 to 55 years, with an average age of 33 years. All the 5 patients underwent laparoscopic SIPS. Observation indicators: (1) surgical situations; (2) postoperative situations; (3) follow-up. Follow-up was performed by outpatient examination, telephone interview and Wechat up to February 2019, including general condition, changes in body weight, body mass index, waistline, blood pressure, percentage of excess weight loss, fasting plasma glucose, glycosylated hemoglobin, blood lipid, and uric acid at 3 months after surgery. Measurement data with normal distribution were represented as
4.Erratum to: Screening for main components associated with the idiosyncratic hepatotoxicity of a tonic herb, Polygonum multiflorum.
Chunyu LI ; Ming NIU ; Zhaofang BAI ; Congen ZHANG ; Yanling ZHAO ; Ruiyu LI ; Can TU ; Huifang LI ; Jing JING ; Yakun MENG ; Zhijie MA ; Wuwen FENG ; Jinfa TANG ; Yun ZHU ; Jinjie LI ; Xiaoya SHANG ; Zhengsheng ZOU ; Xiaohe XIAO ; Jiabo WANG
Frontiers of Medicine 2021;15(2):330-332