ObjectiveTo observe the clinical effectiveness and safety of Qingfei Shenshi Decoction （清肺渗湿汤） combined with western medicine for patients with bronchial asthma of heat wheezing syndrome， and to explore its potential mechanism of action. MethodsEighty-six participants with bronchial asthma of heat wheezing syndrome were randomly divided into treatment group and control group， each group with 43 participants. The control group received conventional western medicine， and the treatment group was additionally administered Qingfei Shenshi Decoction orally on the basis of the control group， 1 dose per day. Both groups were treated for 14 days. The primary outcome measure was clinical effectiveness； secondary outcome measures included traditional Chinese medicine （TCM） syndrome score， asthma control test （ACT） score， pulmonary function indices such as forced expiratory volume in 1 second （FEV₁）， forced vital capacity （FVC）， peak expiratory flow （PEF）， serum inflammatory factor levels including interleukin-4 （IL-4）， tumour necrosis factor-α （TNF-α）， and high-sensitivity C-reactive protein （hs-CRP）， and immune function indices including CD3⁺， CD4⁺， CD8⁺， CD4⁺/CD8⁺. All outcome measures were evaluated before and after treatment. Vital signs were monitored， and electrocardiography， blood routine， urine routine， liver function， and renal function tests were performed before and after treatment. Adverse events and reactions during the study were recorded. ResultsA total of 80 patients completed the trial with 40 in each group. The total clinical effective rate of the treatment group was 97.5% （39/40）， which was significantly higher than that of the control group （85.0%， 34/40， P＜0.05）. After treatment， both groups showed decreased TCM syndrome scores， IL-4， TNF-α， hs-CRP， and CD8⁺ levels， as well as increased ACT scores， CD3⁺， CD4⁺， CD4⁺/CD8⁺， FEV₁， FVC， and PEF levels （P＜0.05 or P＜0.01）. Moreover， the improvements in these indices were more significant in the treatment group than in the control group （P＜0.05 or P＜0.01）. No significant abnormalities in safety indicators were observed in either group， and no adverse events or reactions occurred. ConclusionQingfei Shenshi Decoction combined with conventional western medicine for patients with bronchial asthma of heat wheezing syndrome can effectively improve the clinical symptoms， pulmonary function， and clinical effectiveness， with good safety. Its mechanism may be related to reducing inflammatory factor levels and regulating T lymphocyte subsets to improve immune function.

Objective To analyze the changes in optical coherence tomography angiography (OCTA) parameters in patients with essential hypertension，and to explore the effect of blood pressure on OCTA parameters. Methods A total of 164 patients with essential hypertension were selected and divided into controlled blood pressure group (n=92) and uncontrolled blood pressure group (n=72). OCTA examination was performed on the optic disc and macula of all patients, and the right eyes were selected for analysis. Results There were no significant differences in retinal nerve fiber layer (RNFL) thickness, radial peripapillary capillary (RPC) total vascular density, RPC total small vessel density, perifovea superficial capillary plexus (SCP) vascular density, and perifovea deep capillary plexus (DCP) vascular density between the two groups of patients. There were no significant differences in foveal avascular zone (FAZ) area, FAZ diameter, and fovea retinal thickness between the two groups of patients. The density of the parafovea SCP, parafovea DCP, and fractal dimension (FD) in the uncontrolled blood pressure group were significantly lower than those in the controlled blood pressure group (P＜0.05). Multiple linear regression analysis showed that elevation of blood pressure was a independently related factor of reduced parafovea DCP density (P＝0.026), while there was no correlation between the uncontrolled blood pressure and parafovea SCP density and FD level. Conclusions The blood pressure level is correlated with the parafovea DCP density, while has no correlation with other OCTA parameters in hypertension patients.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.

Affiliated Beijing Chaoyang Hospital of Capital Medical University focus on problem solving.By applying the dual responsibility for one position system and compacting the main responsibility of party and government leaders,the hospital aims to achieve organic integration of party building and business organic integration of party building and businessat the organizational management level.By emphasizing on adopting systematic thinking method and establishing modernized hospital management systems,the hospital aims to achieve integration at the institutional system level.Adhering to the joint efforts of the party building and administrative work and focusing on improving comprehensive service quality,the hospital aims to achieve integration at the behavioral level.By valuing ideological integration and guiding hospital cultural construction with strict political standards,the hospital aims to achieve integration at the cultural level.Through systematic organizational reformation,a new approach to the organismic integration of party building and business in public hospitals has been explored,and a new mechanism with innovative vitality and effective results has been initially formed.