objective: To study the relation of anchorage control and consumption of Nance arch. Methods: J hook anchorage, Nance arch with J hook anchorage, and Nance arch anchorage were used in 15, 12 and 16 cases for orthodontic treatment. All anchorage consumption of the first molar was measured on dental cast. Results: Forward movement of first molar in all of the cases was observed after treatmment( P

Objective:To introduce a self-made film holder for standardized alignment of intraoral film and to evaluate its validity.Methods:The film holder,consisting of film backing,bite block and indicating part,was made of a kind of transparent material.20 patients were photographed using the film holder for serial dental films and another 20 patients were photographed using conventional bitewing instrument.The distance between the cemento-enamel junction and alveolar crest and the distance between cemento-enamel junction of adjacent teeth were measured on the serial films taken in the two groups.Results:The films taken by the use of film holder showed greater reproducibility than those by bitewing.Variables changes were significant smaller in film holder group than those in bitewing group.Conclusion:The film holder can be used as a instrument for standardized alignment of intraoral film.

To push up the quantity of faculty member in higher medical education,and acclimatize them to the social economic development of 21st century,the significance,instructions,contents,approaches and administrations of continuing education for medical faculty members are discussed.The re-education for medical faculty members should be based on the motivation of activity and spontaneity,and the goal of continuing education should be high quantity,differentiated standard and individuation.

Objective To investigate the expression of PTTG and VEGF-C in laryngeal carcinoma and the effect of angiogene-sis .Methods Immunohistochemistry was used to detect the expression of PTTG 、VEGF-C and LMVD in 60 cases of laryngeal car-cinoma and 32 cases of para-carcinoma tissue .D2 40 positive products was used to locate lymphatic endothelial cell cytoplasm and cell membrane ,and count lymphatic microvessel density (LMVD) .Results The expression of PTTG and VEGF-C in laryngeal car-cinoma was significantly higher than that in para-carcinoma tissue(P<0 .05) .In laryngeal carcinoma ,the expression of PTTG and VEGF-C were associated with differentiation ,lymph node metastasis and clinical stage(P<0 .05) ,but independent of clinical classi-fication ,smoking history ,tumor′size ,sex and gender(P>0 .05) .The expression of LMVD in laryngeal carcinoma was significantly higher than that in para-carcinoma tissue(P<0 .05) .The expression of LMVD was associated with lymph node metastasis (P<0 .05) ,but independent of differentiation ,clinical classification ,clinical stage smoking history ,tumor′size ,sex and gender ( P>0 .05) .A significantly positive relation was found between PTTG and VEGF-C(P<0 .05) .And there were positive relation between PTTG and LMVD、VEGF-C and LMVD(P<0 .05) .Conclusion PTTG and VEGF-C might play an important role in the carcino-genesis and development of laryngeal carcinoma .PTTG and VEGF-C could be a prognostic factor of colorectal cancer and a new tar-get of gene therapy .

Objective:To study the e ects of anthopleurin-Q(AP-Q) on potassium currents of ventricular myocytes in rats and guinea pig.Methods:The ventricular cells of guinea pigs and S.D.rats were obtained by enzymatic method.Whole cell patch clamp technique was used to record potassium currents,including transient outward potassium currents(Ito),delayed recti er potassium current(IK) and inward recti er potassium current(IK1).Results:AP-Q 3-100 nmol/L blocked Ito in a concentration-dependent manner with an EC50 value of 10.5 nmol/L.With +50 mV depolarized pulse and 10nmol/LAP-Q,the Ito increased from(13.3?3.4)pA/pFto(19.46?4.3)pA/pF.AP-Q 0.1-100 nmol/Lincreased IK and tail current(IK tail) in a concentration-dependent manner with EC50 value of 4.7 nmol/Land 5.0 nmol/L,respectively.AP-Q 1 pmol/L-100 nmol/Lincrease IK1 in a concentration-dependent manner with EC50 value of 0.2 nmol/L.Conclusion:Augmented e ect of AP-Q on Ito,IK and IK1 may partly explain its e ects of shortening APD and increasing absolute value of RP.

Objective: To explore the impact of environmental temperature exposure on eczema visits. Methods: Eczema clinic data from January 1, 2016 to December 31, 2019 were collected from the Huizhou Dermatology Hospital, and data on meteorological factors (average daily temperature and relative humidity) for the same period were derived from 86 meteorological stations of the Guangdong Provincial Climate Center. A distributed lag nonlinear model (DLNM) was used to assess the lagged effect of environmental temperature exposure on eczema, and a natural smooth spline function was used to control the nonlinear confounding of humidity. Results: There were 254 053 eczema outpatient visits at the Huizhou Dermatology Hospital within four years, with an average of 173.89 visits per day. The relationship between daily average temperature and the number of visits was non-linear (U shape). The risk of eczema increased by 2.20% (1.19%-3.21%) for every 1 ℃ decrease for the low temperature, and increased by 2.35% (1.24%-3.5%) for every 1 ℃ increase for the high temperature. The effect of high temperature was greater than that of low temperature. In all cases, 1.60% (0.44%-2.68%) of eczema outpatient visits were attributed to low temperature and the attributable number was 4 065 (1 128-6 798), while 6.33% (1.40%-10.87%) of eczema outpatient visits were due to high temperature and the attributable number was 16 082 (3 557-27 616). Conclusion: Both high temperature and low temperature are associated with increased risk of eczema.
Humans ; Air Pollution/adverse effects* ; Temperature ; Outpatients ; Cities ; Eczema/epidemiology* ; China/epidemiology* ; Air Pollutants/analysis*