1. Ten cases of fracture of the carpal navicular were observed and analyzed, which were treated by thumb-including short arm cast in the Department of Orthopedic Surgery, Han Kang Sacred Heart Hospital during the period from November 1, 1977 to May 31, 1978. 2. Of the total ten cases eight cases were between the age of twenty and forty. 3. The sites of fracture were confined to the middle one third in ten cases. The fracture lines were-transverse in six cases. 4. There was little difficulty in confirming the diagnosis initially with clinical symptoms and signs and roentgenologic studies available. But, in one case the frature line was not detected by usual roentgenologic studies including the carpal navicular view. 5. Union was obtained from two cases after ten weeks of cast immobilization, from four cases after twelve weeks and from three cases after twenty weeks. In the remaining one case, however, pain was persistent after twenty-four weeks of immobilization. 6. The results of treatment were excellent in four cases and good in five cases so that nine patients could return to their work.
Arm ; Diagnosis ; Heart ; Humans ; Immobilization ; Orthopedics

No abstract available.

No abstract available.
Animals ; Immunohistochemistry* ; Neurons* ; Rats* ; Substantia Nigra*

The relative incidence of cerebral palsy has increased recently over that of poliomyelitis, due to the improvement in the social, medical, and economic status of our country. It is important to check the pathologic reflexes for diagnosis, treatment and prognosis of cerebral palsy. We studied 84 cerebral palsied patients, between 1 to 13 years old, who were treated at our Crippled Childrens Rehabilitation Center. The motor age and pathologic reflexes were checked, and pathologic reflexes were checked, and the relationship between pathologic reflexes and walking was compared. The following results were obtained. 1) With increasing of chronological age, there was a tendericy to increasing of motor age, but the mean motor age did not increase after 8 years in chronological age, and no more than to about 20 months. 2) With increasing of motor age, a tendency to decreasing of frequency of pathologic reflexes was shown. 3) The followings were the most important pathologic reflexes in non walking group: a) positive supporting reaction b) supine lying c) prone lying d) Moro reflex e) asymetrical tonic neck f) protective extensor thrust.
Cerebral Palsy ; Child ; Clinical Study ; Deception ; Diagnosis ; Humans ; Incidence ; Neck ; Poliomyelitis ; Prognosis ; Reflex ; Reflex, Startle ; Rehabilitation Centers ; Walking

BACKGROUND: The patients visiting the primary care complain of the various symptoms. This symptoms may induce the stress or the reverse. In fact the stress can influence the symptoms and signs. So this study was done for the correlation of the symptoms and signs with stress. METHODS: This study was done about the patients visiting the family medicine department of the one university hospital. We collected the all items that can find in the charts for examining the symptoms and signs, and did the requests pater the patients wrote by themselves. The stress test was Psychosocial well being index to be constructed from the General Health Questionnaire. We tested the study by t-test, anova, chi-square, linear logistic regression. RESULTS: The total study numbers were 351. The stress cut-off point was 63 score. The stress group was consisted of 15 males and 43 females. The meaningful symptoms were headache, dizziness, fatigue, weakness, insomnia, anxiety or depression. The meaningful diagnoses were anxiety or depression, tension headache(p<0.05). The meaningful sociodemographic factors were female, housewife or unemployed, menopause, monthly income below 200 ten thousands won. CONCLUSIONS: It was found that the some symptoms and signs were statistically correlated with stress.
Anxiety ; Depression ; Diagnosis ; Dizziness ; Exercise Test ; Fatigue ; Female ; Headache ; Humans ; Logistic Models ; Male ; Menopause ; Primary Health Care ; Sleep Initiation and Maintenance Disorders ; Surveys and Questionnaires

OBJECTIVE: We previously described that Diva is highly expressed in matured metaphase II (MII) oocytes compared to immature germinal vesicle (GV) oocytes in mouse.1 We report here that the expression of Diva transcript as well as protein is oocyte-specific. To elucidate its physiological role in oocyte, the binding partner(s) of Diva has been identified by using immunoprecipitation (IP) followed by Mass Spectrometry. METHODS: NIH/3T3 cells were transiently transfected for 24 h with either empty vector for control or FLAG-tagged mouse Diva construct, and IP was performed with anti-FLAG antibody. The immuno-isolated complexes were resolved by SDS-PAGE on a 12% gel followed by Coomassie Blue staining. For in-gel digestion, 15 bands of interest were excised manually and digested with trypsin. All mass spectra were acquired at a positive reflector mode by a 4700 Proteomics Analyzer (Applied Biosystems, Framingham, MA). Proteins were identified by searching the NCBI nonredundant database using MASCOT Peptide Mass Fingerprint software (Matrixscience, London). RESULTS: Diva-associated complexes were formed in FLAG-tagged mouse Diva-overexpressed NIH/3T3 cells via IP using anti-FLAG-conjugated beads. Among the excised 15 bands, actin and actin-binding proteins such as tropomyosin, tropomodulin 3, and alpha-actinin were identified. Binding between Diva and actin or tropomyosin was confirmed by IP followed by Western blot analysis. Both bindings were also detected endogenously in mouse ovaries, indicating that Diva works with actin and tropomyosin. CONCLUSIONS: This is the first report that immuno-isolated Diva-associated complexes are related to actin filament of the cytoskeletal system. When we consider the association of Diva with actin and tropomyosin, oocyte-specific Diva may play a role in modulating the cytoskeletal system during oocyte maturation.
Actin Cytoskeleton ; Actinin ; Actins ; Animals ; Blotting, Western ; Dermatoglyphics ; Digestion ; Electrophoresis, Polyacrylamide Gel ; Female ; Immunoprecipitation ; Mass Spectrometry* ; Metaphase ; Mice ; Microfilament Proteins ; Oocytes ; Ovary ; Proteomics ; Tropomodulin ; Tropomyosin ; Trypsin

PURPOSE: Most men with benign prostatic hyperplasia (BPH) have bothersome lower urinary tract symptoms (LUTS). This study aimed to investigate the safety and efficacy of high-performance system (HPS) laser photoselective vaporization of the prostate (PVP) for the treatment of BPH in men with detrusor underactivity (DU). MATERIALS AND METHODS: From March 2009, 371 patients with BPH were divided into 2 groups according to the findings of preoperative urodynamic study: 239 (64.4%) patients with bladder outlet obstruction (BOO) and 132 (35.6%) patients with bladder outlet obstruction with detrusor underactivity (BOO+DU). 120 W HPS laser PVP was performed to resolve the BOO. The perioperative data and postoperative results at 1 month and 12 months, including the International Prostate Symptom Score (IPSS), maximum urinary flow (Qmax), and postvoid residual urine (PVR) values, were evaluated. RESULTS: Compared with the preoperative parameters, significant improvements in IPSS, Qmax, and PVR were observed in each group at 1 and 12 months after the operation. In addition, IPSS, Qmax, and PVR were not significantly different between the BOO and BOO+DU groups at 1 and 12 months after the operation. CONCLUSIONS: Surgery to relieve BOO in the patients with BPH seems to be an appropriate treatment modality regardless of the existence of DU.
Humans ; Laser Therapy ; Lower Urinary Tract Symptoms ; Male ; Prostate ; Prostatic Hyperplasia ; Urinary Bladder Neck Obstruction ; Urodynamics ; Volatilization

No abstract available.
Nortriptyline* ; Pharmacokinetics*

No abstract available.
Cicatrix, Hypertrophic* ; Skin*

A gene p53, which is a tumor suppressor gene located on chromosome 17p, regulates cell growth and proliferation, and inactivation of this gene appears to be a common abnormality in many malignant tumors in human. To investigate the prevalence and patterns of p53 protein overexpression and the significance of the p53 protein overexpression as a marker for poor prognosis in transitional cell carcinoma of the bladder which were treated with radical cystectomy, fifty deparaffinized archival specimens from radical cystectomy for transitional cell carcinoma of the bladder were analyzed immunohistochemically to detect overexpression of p53 protein using the mouse monoclonal antibody DO-7 with a standard avidin-biotin immunoperoxidase method. The incidence of p53 expression was 17 of50 (34 per cent) specimens. The p53 expression was associated with histopathologic grade but not with T stage and the status of lymph node involvement. There was no evidence of high recurrence rate, metastasis rate or low survival rate in patients with p53 positive group compared to p53 negative group. But the patients with p53 positive group showed higher T stage and shorter mean survival time than those with p53 negative group. It was not statistically significant. Among many variables evaluated with multivariate analysis, T stage was a significant factor in terms of metastasis, while the status of lymph node involvement was a significant one in terms of survival. In conclusion, the incidence of p53 gene mutation appeared to be higher in invasive and high grade bladder cancer than in superficial and low grade ones. The p53 expression failed to show an unfavorable prognostic factor in transitional cell carcinoma of the bladder treated with radical cystectomy. Prospective studies of large cohorts of specimens are needed to evaluate nuclear overexpression of p53 protein as a prognostic marker in bladder cancer.
Animals ; Carcinoma, Transitional Cell* ; Cohort Studies ; Cystectomy* ; Genes, p53 ; Genes, Tumor Suppressor ; Genes, vif ; Humans ; Incidence ; Lymph Nodes ; Mice ; Multivariate Analysis ; Neoplasm Metastasis ; Prevalence ; Prognosis ; Recurrence ; Staphylococcal Protein A ; Survival Rate ; Urinary Bladder Neoplasms ; Urinary Bladder*