1.The incidence of anemia in 386 patients with esophageal carcinoma undergoing radiotherapy and its effect on prognosis
Yafei NI ; Chaofeng REN ; Jikai XIA
Cancer Research and Clinic 2015;27(10):690-693
Objective To investigate the incidence of anemia among patients with esophageal carcinoma undergoing radiotherapy, and to explore its influence on prognosis.Methods The data of 386 patients with esophageal carcinoma undergoing radiotherapy were collected retrospectively.The survival rates of the 1st, 3rd, 5th year were compared between the anemia group and non-anemia group.Analysis was carried on the impact factors of amenia on the prognosis and other clinical factors.Results The incidence of anemia before radiotherapy was 46.3 % (179/386), and the level of hemoglobin was 116 g/L (49-169 g/L).The incidence of anemia after radiotherapy was 74.2 % (286/386), and the level of hemoglobin was 98 g/L (45-152 g/L).The incidences of anemia between before and after radiotherapy were statistically different (x2 =61.915, P < 0.001).The incidence of anemia before radiotherapy was associated with stage, Karnofsky score, BMI and the weight loss before treatment (P < 0.05).The median survival time of the anemia group was 42 months, while that of the non-anemia group was 52 months, and the difference was statistically significant (x2 =5.002, P =0.025).There were 87.7 % of anemia patients got no treatment.Conclusions The prevalences of anemia before and after radiotherapy are high, and anemia before radiotherapy can decrease the survival rate in esophageal carcinoma patients.Methods should be taken to improve the haemoglobin level in order to increase the survival rate.
2.Clinical Study of Abdominal Acupuncture in Relieving Postoperative Pain of Patients with Mixed Hemorrhoid After Milligan-Morgan Hemorrhoidectomy
Wenjiang WU ; Yuanfeng HAN ; Jie LIN ; Jikai NI ; Zhanbin LUO
Journal of Guangzhou University of Traditional Chinese Medicine 2017;34(3):373-375
Objective To observe the curative effect of abdominal acupuncture on postoperative pain of patients with mixed hemorrhoid after Milligan-Morgan hemorrhoidectomy.Methods A total of 100 mixed hemorrhoid patients with postoperative pain after Milligan-Morgan hemorrhoidectomy under spinal anaesthesia from September of 2014 to December of 2015 were included into the study.The patients were evenly randomized into trial group and control group.The trial group was treated with abdominal acupuncture at acupoints of Shuifen,Guanyuan,Qihai,Sanxing needles under Qihai,lower Fengshi,Tianshu for 15-30 min.The control group was treated with intramuscular injection of Tramadol Injection 0.1 g.Before treatment and 0.5,1,2,3 hours after treatment,the pain visual analogue scale (VAS) scores and body activity scores were recorded.Results (1) After treatment,pain VAS scores of the two groups at different time points were obviously decreased(P < 0.05 compared with those before treatment),and the decrease of pain VAS scores of the treatment group 0.5 hours after treatment was superior to that of the control group (P < 0.05),but there was no significant difference between the two groups at other time points (P > 0.05).(2) After treatment,body activity scores of the two groups at different time points were obviously decreased(P < 0.05 compared with those before treatment),but the difference was insignificant between the two groups(P> 0.05).(3) The average dose of Tramadol Injection used in the trial group was 0.013 ± 0.034 1 g,while was 0.103 ± 0.017 7 g in the control group,the difference being significant (P < 0.05).Conclusion The analgesic effect of abdominal acupuncture is similar to that of Tramadol Injection.For its safety,and being cheap,practical and painless,abdominal acupuncture can be expected to be another option of effective analgesic method for the postoperative pain of patients with mixed hemorrhoid after Milligan-Morgan hemorrhoidectomy.