Objective:To explore the effect between Xuezhikang and rosuvastatin on carotid intima-media thickness (IMT) .Methods :A total of 90 patients with carotid atherosclerosis were randomly and equally divided into control group ,Xuezhikang group and rosuvastatin group according to number table .After six-month treatment ,changes of blood lipid levels and IMT were compared among three groups .Results:Compared with before treatment ,there were significant improvements in blood lipid levels (except high density lipoprotein cholesterol ) and IMT after six months in Xuezhikang group and rosuvastatin group , P<0.05~ <0.01 ;compared with control group after treat-ment ,there were significant reductions in levels of triglyceride [ (2.12 ± 0.97) mmol/L vs .(1.17 ± 0.47) mmol/L , (1.87 ± 0.97) mmol/L] ,total cholesterol [ (5.95 ± 0.65) mmol/L vs . (5.14 ± 0.71) mmol/L ,(4.75 ± 0.64) mmol/L] and low density lipoprotein cholesterol [LDL-C , (3.64 ± 0.45 ) mmol/L vs . (3.01 ± 0.51 ) mmol/L , (2.15 ± 0.55) mmol/L] ,IMT [ (1.15 ± 0.15) mm vs .(1.01 ± 0.08) mm , (0.98 ± 0.02) mm] and total plaque score [ (6.10 ± 2.12) scores vs .(4.61 ± 2.08) scores , (4.59 ± 2.34) scores] in Xuezhikang group and rosuvastatin group , P<0.05~ <0.01 .After treatment ,there were no significant difference in above indexes between Xuezhi-kang group and rosuvastatin group ( P> 0.05 all) except that LDL-C level of rosuvastatin group was significantly lower than that of Xuezhikang group ( P< 0.05 ) .Conclusion:Both Xuezhikang and rosuvastatin can significantly improve carotid atherosclerosis ,and their therapeutic effects are equal .

Objective To understand the status of the sanitary quality in some areas of countryside in Guangxi. Methods The investigation on the type of water source and the water supply was carried out in 9 counties.10 sampling points were established in each observed county.91 water samples were collected totally for the measurement of water quality ,then their sanitary quality was assessed based on the Criteria for Implementing the Hygienic Standards for Drinking Water in Countryside. Results In the observed 9 counties ,15.33% of total population drank water supplied with surface water,and 84.67% with ground water source. Drinking water from centralized water supply system was supplied to 43.16% of total population.In the centralized water supply system,the finished water completely treated by sedimentation and filtration was supplied to 10.57% of the total population,the disinfected finished water was only supplied to 2.96% of the total population,the raw water was directly supplied to 68.66% of the tap water-supplied population without any treatment.The completely-qualified rate of water samples was 20.88% for total 91 water samples,14.81% for surface water samples and 23.44% for ground water samples respectively.The qualified rate of bacterial indexes was 32.61% for water samples collected from centralized water supply system and 20.00% for those from decentralized water supply system. Conclusion Most of the peasants in the investigated 9 counties hadn't been supplied by safe and health drinking water.Contamination of drinking water by microorganisms was the main sanitary problem in water supply in countryside of Guangxi.

Libraries are faced with the crisis of being marginalized in the era of network.Medical academic library should thus adapt to the changing information behaviors of users in study , teaching and scientific research and pro-vide their service according to the user needs-orientedsubject librarian service model , mobile library service model, and sharing commons service model.The service provided in the top 18 medical academic libraries in China according to the 3 models was analyzed, which showed their low popularization rate, insufficient depth and repeti-tion.Measures that should be taken for the solution of such problems were put forward.

he blood supply of corpus callosum is rich, its function is complex, and the incidence of infarction is low. The risk factors and etiology for callosal infarction do not have any difference with the infarction in other parts of the brain. The clinical manifestations of the disease are complex and diverse. The two classical clinical manifestations are callosal disconnection syndrome and frontal-type gait disorder, but hemiplegia, monoplegia, apraxia, and mental retardation are common in clinical practice. The positive rate of CT scan is lower. MRI has higher sensitivity and specificity for callosal infarction. The diagnosis of callosal infarction is not difficult according to the history and imaging examination, however, it needs to be differentiated with other diseases that likely involve corpus callosum. Most of the patients with callosal infarction have good prognosis.

Objective To evaluate the sanitation of the ecological toilet systems used in rural areas. Methods The urine diverting Ecosan toilets in rural areas of Guangxi province were observed for the utilization, maintenance and sanitization. The hygienic evaluation was carried out according to the Hygienic Standards for Excreta Sanitization GB 7959-87. Results The new type of urine diverting Ecosan toilets could meet the requirements of non-hazard treatment of excreta. Conclusion Such toilet system should be developed in most parts of Guangxi.

The maturity and scientific research strength of medical subjects between PRC and India and between PRC and Japan were demonstrated by comparing the scale and production distribution of international papers authors between PRC and India and between PRC and Japan according to the SCADC(2011), SCIE, InCites Statistical Analysis Database, non-regression fitting curve, K-S Test and Rnew fitting goodness, which showed that SCADC(2011) and SCIE displayed 53 specific medical subjects.Lotka distribution and author scale analysis showed that the maturity and scientific research strength of tropical medicine and pediatrics were lower while those of drug abuse, combined traditional and western medicine, primary health care, medical informatics, parasitology, audiology, speech and language pathology were higher in PRC than in Japan.

Object To study the chemical constituents of Hedysarum sikkimense Benth. ex Baker var rigidum Hand Mazz Methods The constituents were repeatedly separated and purified on silica gel column They were identified and structurally elucidated by physicochemical data and spectral analysis Results Nine compounds were obtained Eight of them were lupeol (Ⅰ); isoformononetein (Ⅱ); 3 (4 hydroxyphenyl) 6,7 dimethoxy 4H 1 benzopyran 4 one (Ⅲ); ursolic acid (Ⅳ); docosanoic acid 2,3 dihydroxypropyl ester (Ⅴ); lignoceric acid (Ⅵ); ? sitosterol (Ⅶ) and sucrose (Ⅷ) Conclusion All of them are isolated from this plant for the first time

OBJECTIVE:To observe clinical effect and safety of Shenfu injection combined with linezolid in the treatment of severe pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA). METHODS:In retrospective study,62 MRSA severe pneumonia patients selected from ICU of our hospital during Jun. 2012-Oct. 2015 were divided into observation group (25 cases)and control group(28 cases)according to medication plan. Based on routine treatment,control group was additionally given Linezolid injection 600 mg,ivgtt,bid. Observation group was additionally given Shenfu injection intravenously with initial dose of 60 mL,and then given continuous intravenous infusion of 60 mL at a rate of 20 mL/h,q12 h,on the basis of control group. Both groups were treated for consecutive 2 weeks. Clinical efficacy,bacteriological efficacy,cardiac function indexes and serum levels of inflammatory factors before and after treatment as well as the occurrence of ADR were compared between 2 groups. RESULTS:The clinical response rate of observation group was 88.00%,which was significantly higher than 60.71% of control group,with statistical significance (P<0.05). Bacterial clearance rate of observation group was 72.00%, and that of control group was 64.28%,there was no statistical significance between 2 groups(P>0.05). Before treatment,there was no statistical significance in cardiac function indexes and serum inflammatory factor levels between 2 groups(P>0.05). After treatment,LVEF,SV,CO and CI of 2 groups were increased significantly compared to before treatment,while the levels of TNF-α,IL-6,CRP and PCT were de-creased significantly;the indexes of observation group was significantly better than those of control group,with statistical signifi-cance (P<0.05). No severe ADR was found in 2 groups. CONCLUSIONS:Shenfu injection combined with linezolid effectively improves the cardiac function of patients with MRSA severe pneumonia,enhances the anti-inflammatory effect,and have a very significant clinic effect with good safety.

Objective To investigate the use of component N400 of the event-related potentials (ERPs) elicited by Chinese idioms ending with matching and nonmatching words to explore the cognitive patterns and processing mechanisms elicited by Chinese characters. Methods Sixty-two right-handed healthy adults (age 19-50 years) , were presented with Chinese idioms ending with words with the same pronunciation but different form and meaning, words with similar forms but different pronunciation and meaning, words with same meaning but different pronunciation and form, and words with different pronunciation, form and meaning. A Guangzhou Runjie WJ-1 instrument was used to record component N400 of the potentials evoked. Results N400 showed a midline distribution , and could be detected under electrodes Fz, Cz and Pz. Significant differences were found in N400 latencies and amplitudes between matching and nonmatching ending-words. Compared with idioms with matching ending-words, N400 latencies were prolonged and amplitudes increased in nonmatching cases. The observed changes in N400 latencies and amplitudes were related to stimulus types, and the longest latency and largest amplitude were e-licited by ending-words with different pronunciation, form and meaning. No gender difference in N400 latency or amplitude was observed. Conclusions Compared with Western phonetic words, Chinese ideographic words are more flexible stimuli for N400 research, offering 3 dimensions for change: pronunciation, form and meaning. The N400 features elicited by matching and nonmatching ending words in Chinese idioms are mainly determined by the meaning of the word.