Objective:To study the relationship between perfectionism and interpersonal problems as well as loneliness of college students.Methods:638 college students were tested with Perfectionism Self-Presentation Scale(PSPS),Inventory of Interpersonal Problems(IIP-32)and UCLA Loneliness Scale(UCLA).Results:There was significant correlation between three kinds of perfectionism and interpersonal problems as well as loneliness.And the three kinds of perfectionism could well predict interpersonal problems(Need to appear perfect:?=-0.089;need to avoid appearing imperfect:?=0.268;need to avoid disclosing imperfections:?=0.287).Need to appear perfect and interpersonal problems could predict loneliness(?=-0.114,?=0.605).Furthermore,need to appear perfect,need to avoid appearing imperfect and need to avoid disclosing imperfections could influence loneliness via interpersonal problems.Conclusion:The need to appear perfect could be beneficial to relieve interpersonal problems and loneliness.While the need to avoid appearing imperfect and the need to avoid disclosing imperfections could increase interpersonal problems and loneliness.Interpersonal problems could serve as moderator between perfectionism and loneliness.

There is a close relationship between brain structure and cognitive disturbances in schizophrene. The paper discussed the disorder of the brain's structure, cognitive dysfunction and the relation between them in the schizophrenia patients,which based on the brain pathology and clinical studies. At last,it analyzed the contribution of the verbal fluency tests to the assessment of schizophrenia. The paper could help to understand the schizophrenia pathogeny more deeply,which can beneficial to the clinical prevention and therapy.

Objective:The present study explored the effects of test-anxious on the color naming of the words which related to tests. Methods:Utilizing the research model of Stroop effect,the high test anxious individuals and low test anxious individuals were asked to name the colors of words which related to test and the colors of the words which not related to words. Results:Test-anxious had remarkable interference effect to the color naming of the words related tests made by the high test anxious individuals, compared to the color of the words which unrelated to test, the naming response time of the high anxious subjects were prolonged 56 ms to test-related words (556.0?58.2/500.0?46.5,t=2.56, P=0.016), the naming response time of the low anxious subjects were promoted 40 ms, they had shorter reaction time to test-related words (470.0?51.1/510.0?45.7,t=-6.76, P

Objective:To explore gender difference of adolescent's sexology.Methods:Twenty-three studies about adolescent sexology from 1994 to 2005 were collected for meta analysis.Results:When facing first menstrual flow, more girls express fear than the counterpart situation of boys first facing spermatorrhea (effective value 0.49, 95% CI 0.45~0.53). Boys and girls had no difference as with school as the source of sex knowledge. Girls got sex knowledge more frequently from parents than boys, the later got more from media and books. Boys had more sex fantasy, stronger sex desire and actually more sex activities than girls (effective values were 4.47, 3.41, 1.59 relatively, with 95% CI were 4.06~5.13, 3.10~3.47, 1.37~1.86).Conclusion:There are obvious gender differences in adolescent sexology.

Objective: To investigate moderating role of sense of humor to the relationship between stressful events and mental health. Methods: 836 middle-school students were investigated by MSHS, ASLEC and GHQ-20. Results: Sense of humor had a positive effect on students’ mental health, and strong humor could deduce the level of anxiety and depressed emotion. Sense of humor could buffer the relationship of stressful events and depression, but it could not adjust the relationship of stressful events with self-affirmation and anxiety. Conclusion: Sense of humor has a moderating effect on the stressful events and some aspects of mental health.

Objective To obtain genes encoding the novel molecules for diagnosis of schistosomiasis. Methods The cDNA library of Schistosoma japonicum (Sj) schistosomula of day 15 post-infection was screened with positive patients sera,and the inserts of positive clones were sequenced. Then the sequences were compared with all sequences in GenBank database by Internet. The positive clones were analyzed by the software in bioinformatics. Results After three rounds of screening,15 positive clones were obtained,and among them 11 clones had the meaningful sequences,in which 5 genes coding for Sj mitochondrion,1 gene coding for Sj myosin and the others were SjCHGC05315,SjCHGC01371,SjCHGC04782,SjCHGC05166,SjCHGC09769,respectively. Conclusion Immunological screening by using positive patients sera can be used to discover Sj antigen genes with a potential value for diagnosis.

Tetraspanin 2-A(SjTsp2-A) gene was amplified by PCR.pcDNA3.1(+)/SjTsp2-A recombinant plasmids were constructed and transformed into E.coli DH5?.Twenty four BALB/c mice were randomly divided into pcDNA3.1(+) /SjTsp2-A group(A),pcDNA3.1(+)/SjGST group(B) and pcDNA3.1(+) group(C).Each mouse was injected through musculus quadriceps femoris by three times(two weeks interval) respectively with 100 ?g pcDNA3.1(+)/SjTsp2-A,pcDNA3.1(+)/SjGST,or pcDNA3.1(+).At two weeks after the final inoculation,mice were each challenged by 40?2 cercariae of S.japonicum.Forty-five days after infection,all mice were sacrificed,the number of worms collected and eggs in liver tisssue was counted.Anti-pcDNA3.1(+)/SjTsp2-A antibody was detected by ELISA and protein expression in quadriceps muscle by immunohistochemical staining.The worm reduction rate(44.4%) and egg reduction rate(28.4%) of group A was higher than those of group B and C(P

Objective To obtain genes encoding the novel molecules for diagnosis of schistosomiasis.Methods Juvenile S.japonicum cDNA library was immunoscreened to obtain positive clones.By DNA sequencing and sequence analysis,the target gene was amplified by PCR and subcloned into prokaryotic plasmid pET28a.The recombinant plasmid was transformed into E.coli BL21 followed by expression of the protein induced by IPTG.The protein was identified by Western blotting.Results 34 positive clones were obtained,24 of which were chosen to be sequenced,13 of which were Sj22600 gene.The protein were recognized with sera of infected rabbits and patients with acute and chronic schistosomiasis by Western blotting.Conclusion The gene coding for Sj22600 membrane protein was screened with high frequency in the cDNA library.The E.coli BL21 transformed with the recombinant plasmid can express the fusion protein,which shows immunoactivity.

The protective effect and mechanism of Oroxylin A, a naturally occurring compound in Scutellaria baicalensis Georgi, was investigated in this study. Isoproterenol administration to rats triggered classic cardiac failure, as demonstrated by objective parameters of cardiac dysfunction. Intragastric administration of oroxylin A at the dose of 25, 50 and 100 mg/(kg·d)significantly improved deranged cardiac parameters in the isoproterenol-induced heart failure model in a dose-dependent manner. At the same time, oroxylin A markedly ameliorated cardiac histological changes and down-regulated serum levels of various neuroendocrine factors including norepinephrine, aldosterone, brain natriuretic peptide, endothelin 1, angiotensin II and so on. Mechanistically, augmenting autophagy of myocardial cells via the inhibition of AKT1-RPS6KB1 signaling contributed to the improvement of isoproterenol-induced rat heart failure by oroxylin A. Taken together, these results suggest that oroxylin A ameliorates heart failure through promoting autophagy in myocardial cells.

Objective:To explore the design of an evaluation index system with feasibility and appropriateness, and to conduct cloud model evaluation, in order to provide reference for the high-quality development of public traditional Chinese medicine(TCM) medical institutions in China.Methods:The Delphi method and analytic hierarchy process were used to construct an evaluation index system for public TCM medical institutions and calculate the index weights. Then the cloud model theory was applied to comprehensively evaluate the index system.Results:The index system of TCM medical institutions including 5 primary indicators and 12 secondary indicators of " external governance" module and 9 primary indicators and 62 secondary indicators of " internal management" module was constructed. The cloud model of the index system was(4.608, 1.022, 0.151), and the cloud rank was in the range of " very good" .Conclusions:The indicator system constructed in this study is relatively objective, scientific, and reasonable. While ensuring the accuracy and credibility of the evaluation results, it also adds evaluation information, which has certain guiding significance for promoting the high-quality development of public TCM medical institutions.