Objective: To evaluate the significance of occlusion of hemihepatic inflow plus major ipsilateral hepatic veins in anatomic hepatectomy. Methods: One hundred and two cases were divided into 3 groups for anatomic hepatectomy: Group A (hemihepatic inflow plus major hepatic vein occlusion, n=42), Group B (hemihepatic inflow occlusion, n=30)and Group C (Pringle maneuver, n=30). The amount of intraoperative bleeding, time of operation, postoperative liver function, liver function recovering and complications were compared. Results: The average amount of hemorrhage in Group A, Group B and Group C were(453.5?87.9)、(612.8?101.6)and(646.7?136.6)mL, respectively. The mean blood loss in Group A was significantly more than that in Group B and Group C (P0.05). The levels of serum alanine transaminase (ALT)and bilirubin of 3rd and 6th day of postoperation in Group A and Group B were significantly lower than that in Group C, while the level of serum albumin in Group A and Group B was significantly higher than that in Group C(P0.05). Incidence of ascites in Group C was significantly higher than in Group A and Group B (P

Objective To investigate the effect of Botulinum toxin type A(BTXA)and rehabilitation intervention on upper limb Brunnstrom stages and ADL performance of stroke patients. Methods In a randomized controlled trial, 30 patients were allocated to either an experimental group (n=15) that received BTXA injection into muscles of the affected arm or to a controlled group (n=15). All patients' Brunnstrom stage and MAS stage were ≥gradeⅡ. All the patients were treated with rehabilitative techniques. The intervention was applied for 3 months. All were evaluated for the severity of spasticity (Modified Ashworth Scale,MAS),the level of impairment (Brunnstrom assessment and Fugl-Meyer upper limb test) and disability(Functional Independence Measure,FIM) before and after 1 week, 1,2,3 months of treatment. Results Patients who received BTXA had significant reduction of muscle tone (P

Objective To investigate the therapeutic effect of intra-arterial thrombolysis (IATT) in acute cerebral infarction(ACI). Methods 15 patients with ACI were treated with IATT using Urokinase(UK). All patients were assessed by DSA before and after IATT. The stroke scale(ESS and NIHSS) and Barthel Index(BI) were used before and 2 h,48 h,15 d ,30 d after treatment for appraising thearpeutic effect . Results After IATT, the sides of obliterated middle cerebral artery in 12 patients were completely re-circulated. Compared with before IATT, the scores of ESS, NIHSS and BI were significantly improvement at 2 h,48 h,15 d and 30 d after IATT(P

Objective To observe the effect of Shoutaiwan on improving clinical pregnancy rate of in vitro fertilization-embryo transfer (IVF-ET). Method Eighty people, who were easy to be followed up and pregnant with the assistant of IVF-ET by the tube-baby centre of Shenzhen Urology Surgical Hospital of Zhongshan Medical University from 2001 to 2003, were divided into two groups randomly with 40 people for each. Treatment group, after embryo transfer, were normally injected progesterone and auxiliary treated of traditional Chinese Medicine according to syndrome differentiation. The comparing group were only injected progesterone. The curative effect was observed and compared. Result In 40 cases of treatment group, 23 cases were pregnant, clinical pregnant rate was 57.5%, the average level of progesterone was (22.45?1.31)?g/L, pregnant abortion rate was 13.0%. In 40 cases of comparing group, 12 cases were pregnant, clinical pregnant rate was 30.0%, the average level of progesterone was (10.18?0.89)?g/L, pregnant abortion rate was 25%. There were significant differences in the clinical pregnant statistical rate, the average level of progesterone and pregnant abortion rate between the two groups. Conclusion It’s more effective that the syndrome differentiation method based on Shoutaiwan than progesterone treatment only in improving clinical pregnant rate and reducing pregnant abortion rate of IVF-ET.

Transoral laser microsurgery (TLM) has developed more than 40 years in the treatment of laryngeal cancer. TLM is especially important in the minimally invasive surgery of laryngeal carcinoma. Compared with the traditional open surgery, it is a major breakthrough, which has the significant advantages such as safety, effectiveness, low rate of local recurrence and high rate of larynx preservation. Not only can cure early laryngeal cancer, but also more and more the use of TLM in advanced supraglottic and glottic laryngeal cancer were reported. This article will review the characteristics, indications, superiority, surgical options and efficacy of the TLM in laryngeal carcinomas.
Carcinoma, Squamous Cell ; Glottis ; Humans ; Laryngeal Neoplasms ; surgery ; Laryngectomy ; Laser Therapy ; Microsurgery ; Neoplasm Recurrence, Local ; Organ Sparing Treatments ; Otorhinolaryngologic Surgical Procedures

Objective To study diffusion characteristic, diffusion-weighted imaging (DWI) technique and its value in lumbar osteolytic metastases. Methods Twenty patients with lumbar osteolytic metastases and 20 controls were performed with sagittal SE T_1WI, FSE T_2WI, fat saturation FSE T_2WI(FS-FSE T_2WI)and single-shot spin-echo echoplanar DWI, respectively. Contrast noise ratios (CNRs) of the metastases on various series were compared. On DWI, signal attenuation ratios (SARs) and apparent diffusion coefficients (ADCs) of lumbar osteolytic metastases and normal vertebrae were analyzed. Results (1) Routine MRI appearance: There were 23 lesions in the 20 patients. The signal intensity of all lesions showed hypointense on SE T_1WI, hyperintense on FS-FSE T_2WI and DWI, and mixed signal intensity (5 cases), isointense (12 cases) or slight hyperintense (6 cases) on FSE T_2WI. (2) CNR: The CNRs of patient group on FSE T_2WI(5.70?3.82)were lower than those on SE T_1WI(25.62?11.73), FS-FSE T_2WI(23.37?7.48)and DWI (b=600 s/mm2)(24.69?9.87)(U values were 5.393, 6.359, and 5.547, respectively,P

Aim To investigate the effect of intrathecal injection of CCR2 antagonist on pain behaviours,spinal astrocytes activation in the spinal cord in a rat model of bone cancer pain. Methods Forty female SD rats weighing 150 ~180 g were randomly divided into five groups ( n=8 each ):(Ⅰ) sham group;(Ⅱ) sham +RS102895 group;(Ⅲ) bone cancer pain group;(Ⅳ) bone cancer pain + DMSO group;(Ⅴ) bone cancer pain+RS102895 group. Rats received i. t. injections of either RS102895 (3 g·L-1 ) 10 μl or 10%DMSO 10 μl at the time of 10-12 days after the operation. Bone cancer was induced by intra-tibial inoculation of 1 × 105 Walker 256 breast cancer cell. Mechanical hind paw withdrawal threshold test was performed one day before and at 3rd,6th,9th, 10th,11th and 12th days after surgery. Immunofluorescence was used to observe the activation of the spinal astrocytes. Results Compared with group Ⅰ, the rats in bone cancer pain group appeared obvious mechanical hyperalgesia (Ⅲ、Ⅳ、Ⅴ) ,the volume,shape and mean optical den-sity ( MOD) of spinal astrocytes could be seen obvious-ly increased,groupⅡhad no obvious statistical signifi-cance (P>0. 05). Compared with group Ⅳ ,i. t. in-jections of RS102895 increased the paw mechanical withdrawal threshold, suppressed the action of astro-cytes,reduced the MOD of spinal astrocytes. Conclu-sion CCR2 might participate in the formation of bone cancer pain via activating spinal astrocytes. CCR2 will be a potential target for the treatment of bone cancer pain.

Objective The purpose of the study was to characterize the X-ray and CT findings of ameloblastomas of the jaw.Meth-ods X-ray (n=9)and CT (n=20)findings of 20 patients with pathologically proven ameloblastomas of the jaw were obtained.Image features included location,size,shape,density of the lesion,and changes of adjacent bone were assessed.Results 1 9 cases were located in the mandible,including 10 cases in the molar-ramus region,four cases in the whole half of the mandible body,two cases in the whole half of the mandible body and the opposide mantum,one case in the whole mandible body,two cases in the anterior teeth region and mantum.One case was located in the molar region of the maxilla.Three cases were uniocular and 17 cases were multiocular in shape.All lesions caused expansile changes in the adjacent bone,including expanding towards the lip and bucca(n=15),the lingua(n=3),and expanding uniformly(n=2).The interruptions of the surrounding bone cortex were demonstrated in 1 9 cases.Conclusion There are some characteristic imaging find-ings for ameloblastomas of the jaw.Correct preoperation dignosis can be made on the basis of imaging findings.

Objective To detect the changes in protein profile of rats'lung inhaled radon using two- dimensional electrophoresis(2-DE)and MS.Methods Male Wistar rats were exposed to radon with the cumulative dose up to 100,200 and 400 working level months(WLM).The total proteins of rats'lung were extracted and isolated by 2-DE.The different protein expressions were analyzed with ImageMaster 2D Platinum software and obviously altered proteins were digested by trypsin and identified by MALDI-TOF-MS.Resuits Comparison of the 2-DE images between the control and radon-exposed groups indicated 14 up-regulated and 9 down-regulated protein spots,15 of which were identified by MALDI-TOF or MALDI-TOF/TOF MS.Conclusions The 2-DE image of radon groups'lung has changed,and the lung damage effect of radon is related to some proteins.

Objective:To evaluate the value of CT in the diagnosis of skeletal metastases from hepatoma.Methods:27 patients proved by clinical or pathological materials were analysed retrospectively.Results:All the lesion were osteolytic on CT scans.The most frequently involved areas were spine(26%),ribs(22%),pelvis(19%)and femur(11%).Conclusion:CT scan is superior to X-ray plain flims in showing the lesions.Most foci can be diagnosed accurately.