[Objective] To observe the cure effect of Qianlishu Pil combined with hydrochloric acid doxycycline and Hytrine on chronic nonbacterial prostatitis(CNP). [Method] Select 264 cases of CNP, randomly divide them into control and treatment groups, n=132 for each. The control group was treated with hydrochloric acid doxycycline and Hytrine for 2m; the treatment group, with combined Qianlieshu Pil with hydrochloric acid doxycycline and Hytrine for 2m;make analysis and comparison of 2 groups after treatment. [Result] The effect and clinical signs recovery time were better in treatment group than control one; the total effective rate was 88.9% for treatment group, and 53.8% for control one, the comparison of them had difference of statistical meaning. [Conclusion] The combination of Qianlieshu Pil , hydrochloric acid doxycycline and Hytrine has marked cure effect on CNP.

Objective. To study the role of endogenous carbon monoxide (CO) in endotoxin shock. Methods. The changes of CO levels and the effects of zinc protoporphyrin IX (ZnPP),an inhibitor of heme-oxygenase (HO), in endotoxin shock and the efficacy of hemin,an inducer of HO were investigated.Results. The plasma CO levels were found to be significantly increased during the course of endotoxin shock. Injection of ZnPP was shown to abrogate the endotoxin-induced hypotension and metabolic derangements markedly. Administration of hemin to healthy rabbits revealed the hypotension and metabolic derangements similar to the animals given endotoxin.Conclusion.CO is a newly found endogenously produced mediator which may play an important role in the pathogenesis of endotoxin shock.