1.The portable low power military ECG for triage
Chinese Medical Equipment Journal 2004;0(09):-
The military portable ECG for triage is a kind of minitype monitoring equipment for life information for the purpose that the ambulanceman carry through first aids in frontline. Life information of the wounded will be acquired exactly and quickly applying with this equipment, then quickening the triage and reducing the casualties. The system is based on C8051F310 single chip microcomputer, applying with high accuracy, low offset drift instrumentation amplifier AD620 and ultra low power LCM LMS019 to display real-time and accurate ECG signal sampled. The equipment is easy to use and inexpensive, suitable for mass requirement of our field army.
2.Curative effect ofDan'e-Fukang soft extract for dysmenorrhea associated with endometriosis
Jiewen SHEN ; Desan ZHENG ; Yide ZHI
International Journal of Traditional Chinese Medicine 2014;(11):994-996
Objective To investigate the efficacy of Dan'e-Fukang soft extract for dysmenorrhea associated with endometriosis.Methods A total of 88 patients with dysmenorrhea associated with endometriosis were randomly recruited into a treatment group and a control group. The patients in the control group were treated with gestrinone, while the patients in the treatment group were treated withDan'e-Fukang soft extract. The therapeutic efficacy, improvement of dysmenorrhea and drug safety after the treatment were observed in both groups.Results The total effective rate of in the treatment group(95.45%, 42/44), was apparently higher than that in the control group(81.82%, 36/44)(χ2=4.062,P<0.05). The dysmenorrhea improvement in the treatment group was better than that in the control group and also better than that before treatment in both groups(allP<0.05). The adverse reaction rate in the control group(22.73%,10/44) was higher than that in the treatment group(9.09%, 4/44)(χ2=5.906,P<0.05).ConclusionsDan'e-Fukang soft extract has a definite clinical efficacy for dysmenorrhea associated with endometriosis, can ameliorate the symptoms of dysmenorrhea.
3.Detection and monitoring technologies for life signals
Jiewen ZHENG ; Taihu WU ; Zhengbo ZHANG ; Zhen WAN
Chinese Medical Equipment Journal 2003;0(12):-
The detection and monitoring of life signals such as heartbeat, respir ation, bloodpressure and temperature are often used to determine the patient's death. On the basis of the theory of military medical service, this paper discus ses life signals detection and monitoring technologies in the field of military medicine. With the progress of sciences, technologies and informatization of Chi nese PLA, life signals detection and monitoring technologies, based on informati on technology, microelectronic technology, communication technology and etc, wil l be more and more important in the development of digital medical equipment.
4.Analysis of the related factors on scores of the clinical dietitians' post-training exam in China
Gang WANG ; Yaoguang ZHENG ; Ning WANG ; Jiewen ZOU ; Quanghui ZHANG
Chinese Journal of Medical Education Research 2016;15(5):433-436
Objective Based on the analysis of relevant factors on scores of the first clinical dietitian post-training examination (CDPTE) in China,to explore the clinical dietitians' post competency evaluation basis.Method 108 students who completed the clinical nutritionist training (60 physicians,nurse or technician 48) were imposed comprehensive evaluation designed according to the concept of post competency.Through analysis and comparison,the correlation factors of the candidates' passing rate and their mastering rate of the module were studied.Results The results of all the candidates' comprehensive theoretical examination increased with the degree and the source of the candidates.Among them,the college students' pass rate was 76.47%,undergraduates' pass rate was 86.21%,Graduates' pass rate was 96.97%;the pass rate in western region was 85%,the central part was 85.71%,the eastern part was 89.55%.All the candidates' knowledge module mastery rate in the comprehensive examination of the theory from high to low in order was:for hospital diet (73.7%),enteral nutrition and parenteral nutrition (72.7%),public nutrition (70.7%),nutrition screening and assessment (66.7%),common nutrition related diseases (65.4%),clinical nutrition related health students regulations,medical psychology and ethics basic knowledge (40.0%).The examination pass rate was related to the educational level of the examinee and the source area,while the knowledge module mastery rate was closely related to the work of clinical nutrition.Conclusion We concluded that the CDPTE could objectively reflect the candidate's clinical competence and professionalism and it was designed on the basic principle of post competency.CDPTE has a positive significance for scientific assessment of clinical dietician,guide for training,and evaluation of training effects as well.The scores of CDPTE can objectively reflect the examinees' clinical competence and professionalism and CDPTE can achieve the goal of evaluating the candidates' competency,and it is of practical significance for scientific evaluation of clinical practice,guiding learning and evaluating the training effect.
5.Study on perceived fatigue evaluating model during simulated load carriage.
Jiewen ZHENG ; Yuhong SHEN ; Chenming LI ; Yafei GUO ; Pengfei REN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2015;33(6):444-447
OBJECTIVETo establish a perceived fatigue evaluating model during simulated load carriage that is based on objective variables through analyzing the characteristics and trends of shoulder force, shoulder pressure, waist pressure, back pressure, and perceived fatigue, and to provide an analytical technique for research on load carriage.
METHODSA 50-min simulated walking (at a speed of 5 km/h and a slope of 0%) experiment including 14 healthy male adults was conducted under four levels of backpack payloads (25, 29, 34, 37 kg). Shoulder force and trunk pressure were sampled simultaneously and analyzed with time- and frequency- domain methods. Multivariable linear regression was used to build a perceived fatigue evaluating model during load carriage.
RESULTSThe perceived fatigue evaluating model based on shoulder force, trunk pressure distribution ratio, load, and body mass index (BMI) was established. Its adjusted determination coefficient (aR2) was 0.709 and the absolute percentage error (APE) at the end of the experiment was less than 20%. The goodness of fit of the model based on frequency-domain independent variables was much higher compared with the model based on time-domain independent variables. The addition of BMI that represents the individual differences to the model obviously improved the goodness of fit.
CONCLUSIONThe perceived fatigue evaluating model established in this study does not rely on the physiological changes of individuals, and thus can be used to establish an evaluation system for human load carriage with dummy as a substitution for human in experiments and to provide a scientific basis for efficient human load carriage.
Adult ; Fatigue ; Humans ; Male ; Models, Theoretical ; Pressure ; Walking ; Weight-Bearing
6.Wearable Concurrent Monitoring System for Physiological Parameters
Zhengbo ZHANG ; Mengsun YU ; Xianliang ZHAO ; Taihu WU ; Jiewen ZHENG
Space Medicine & Medical Engineering 2006;0(01):-
Objective To design a wearable physiological monitoring system for acquiring and monitor-ing vital signs non-intrusively and concurrently.Methods All bio-sensors were embedded in an elastic shirt for detecting physiological parameters with wearable technology.A patented respiratory inductive plethysmography technology was used to measure respiratory function,two sensors were woven into the jerkin around the patient's chest and abdomen.A three-lead,single channel ECG measures heart rate,and a three-axis accelerometer records posture and activity level.An NTC thermometer embedded in the shirt measures the body temperature.Results An elastic jerkin with embedded sensors that collect and continuously monitor respiration,cardiac,temperature,posture and activity signals was fabricated.Conclusion This wearable physiological monitoring system can record multiple parameters non-intrusively and concurrently.It can act as an useful platform for further researches.
7.Analysis of diagnosis and therapy for late onset elderly asthma
Xiaohe ZHENG ; Hanguang YU ; Ling XIAO ; Zhongsheng ZHENG ; Wenping YU ; Chaoqin CHEN ; Jiewen WU
Chinese Journal of Primary Medicine and Pharmacy 2010;17(16):2214-2215
Objective To analyze and summarize the clinical features of delayed occurrence of senile asthma,to add the knowledge and understanding of the disease. Methods To retrospectively analyze clinical data of the cases of senile asthma treated in our hospital,all the cases were divided into groups of early onset senile asthma and delayed occurrence senile asthma,according to the age of first onset.Then related indexes were analyzed,to summarize the clinical features of group of delayed occurrence of senile asthma. Results There were 28 cases of delayed occurrence of senile asthma,accounting for 34.6% of total cases.Compared to early onset group,there was no significant difference (all P>0.05) between two groups for the following items such as age,allergic history and positive rate of family's history,disease causes,clinical symptoms,basic diseases and complications,proportion of severe cases,rate of misdiagnosis and mistreatment,proportion of standardized treatment and un-standardized treatment,prognosis of diseases and mortality.Both groups had low rate of knowledge and application on PEF monitoring equipment and ACT score.The period of misdiagnosis and mistreatment for delayed occurrence group was shorter than the early onset group (P<0.05=; the seasonal nature and day and night pattern was significant in delayed occurrence group (P<0.05=. Conclusion Late onset elderly asthma had the features such as shorter course of the disease,relatively obvious onset rule during day and night,and obvious symptoms during night,which are different from that of early onset group.
8.Computer simulation study on physiological feedback parameters during chest compression.
Guang ZHANG ; Jiewen ZHENG ; Peng ZHAO ; Yuxiao WANG ; Shaowen QIAN ; Hengzhi LU ; Taihu WU
Journal of Biomedical Engineering 2012;29(6):1032-1040
To have a thorough understanding of the CPR quality based on patients' various physiological states, the doctors must do something to simulate the chest compression physiological feedback parameters (CCPFP). The CCPFP simulation plays an important role in raising efficiency of CPR training and improving chest compression quality. In this study, the CCPFP, including cardiac output (CO), coronary perfusion pressure (CPP), partial pressure of End-tidal CO2 (PETCO2) and mean arterial relaxation pressure (MARP), was simulated using Charles F. Babbs' Model. Simulation results showed that the effect of compression depth upon CCPFP was important in the range of 2-6 cm, whereas compression rate had little effect on the CCPFP higher than 100/min; the thoracic factor is inversely proportional to the CCPFP with fixed compression depth and compression rate. The CCPFP simulation can be implemented at the various physiological statuses, and verified well with the animal experimental results and the clinical results.
Blood Pressure
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physiology
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Carbon Dioxide
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blood
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Cardiac Output
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physiology
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Chest Wall Oscillation
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Computer Simulation
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Feedback, Physiological
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physiology
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Humans
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Models, Biological
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Partial Pressure
9.Comprehensive testing system for cardiorespiratory interaction research.
Zhengbo ZHANG ; Buqing WANG ; Weidong WANG ; Jiewen ZHENG ; Hongyun LIU ; Kaiyuan LI ; Congcong SUN ; Guojing WANG
Journal of Biomedical Engineering 2013;30(2):395-402
To investigate the modulation effects of breathing movement on cardiovascular system and to study the physiological coupling relationship between respiration and cardiovascular system, we designed a comprehensive testing system for cardiorespiratory interaction research. This system, comprising three parts, i. e. physiological signal conditioning unit, data acquisition and USB medical isolation unit, and a PC based program, can acquire multiple physiological data such as respiratory flow, rib cage and abdomen movement, electrocardiograph, artery pulse wave, cardiac sounds, skin temperature, and electromyography simultaneously under certain experimental protocols. Furthermore this system can be used in research on short-term cardiovascular variability by paced breathing. Preliminary experiments showed that this system could accurately record rib cage and abdomen movement under very low breathing rate, using respiratory inductive plethysmography to acquire respiration signal in direct-current coupling mode. After calibration, this system can be used to estimate ventilation non-intrusively and correctly. The PC based program can generate audio and visual biofeedback signal, and guide the volunteers to perform a slow and regular breathing. An experiment on healthy volunteers showed that this system was able to guide the volunteers to do slow breathing effectively and simultaneously record multiple physiological data during the experiments. Signal processing techniques were used for off-line data analysis, such as non-invasive ventilation calibration, QRS complex wave detection, and respiratory sinus arrhythmia and pulse wave transit time calculation. The experiment result showed that the modulation effect on RR interval, respiratory sinus arrhythmia (RSA), pulse wave transit time (PWTT) by respiration would get stronger with the going of the slow and regular breathing.
Algorithms
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Artifacts
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Autonomic Nervous System
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physiopathology
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Diagnosis, Computer-Assisted
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methods
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Electrocardiography
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Equipment Design
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Heart
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physiology
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Humans
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Lung
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physiology
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Monitoring, Physiologic
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instrumentation
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methods
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Respiration
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Respiratory Mechanics
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physiology
10.Role of thromboelastography in assessing the risk of spontaneous bleeding in patients with liver cirrhosis
Decui PEI ; Sisi WEN ; Haichun HU ; Xiuxia ZHENG ; Linfei LI ; Jiewen DENG
Journal of Clinical Hepatology 2021;37(7):1582-1588.
ObjectiveTo investigate the association between thromboelastography (TEG) parameters and bleeding in patients with liver cirrhosis and whether TEG can be used to predict the risk of spontaneous bleeding in patients with liver cirrhosis, and to provide a basis for its preventive treatment. MethodsA retrospective analysis was performed for the clinical data of 174 patients with liver cirrhosis who attended Huadu People’s Hospital from May 2018 to April 2020 and did not receive invasive procedure, and according to the condition of bleeding, they were divided into non-bleeding group(n=64), gastrointestinal bleeding group(n=61), and mucocutaneous/oronasal bleeding group(n=49). The medical record system and laboratory information system were used to collect related information and laboratory test results for statistical analysis. The t-test was used for comparison of normally distributed continuous data between two groups; an analysis of variance was used for comparison between multiple groups, and the least significant difference t-test was used for further comparison between two groups. The Mann-Whitney U test was used for comparison of non-normally distributed continuous data between two groups, and the Kruskal-Wallis H test was used for comparison between multiple groups. MedCalc software was used for receiver operating characteristic (ROC) curve analysis, and the area under the ROC curve (AUC) was calculated for commonly used coagulation markers and TEG parameters in predicting the risk of bleeding in patients with liver cirrhosis. Cut-off value, sensitivity, specificity, positive predictive value, and negative predictive value were determined, and the Z test was used for comparison of indices in predicting mucocutaneous/oronasal bleeding. ResultsOf all 174 patients, 110 (63.2%) experienced spontaneous bleeding, among whom 61 (55.5%) had gastrointestinal bleeding and 49 (44.5%) had mucocutaneous/oronasal bleeding. There were significant differences in maximum amplitude (MA) and K between the bleeding group and the non-bleeding group (t=2.241 and -2.605, both P<0.05). There were significant differences between the mucocutaneous/oronasal bleeding group and the non-bleeding/gastrointestinal bleeding groups in platelet count (PLT) and the TEG parameters of clot formation time, a-angle, MA, and coagulation index (CI) (F=3.947, H=12.867, F=4.007, F=8.498, F=5.420, all P<0.05). Among the TEG parameters, reaction time and Lys30 were generally within the normal range, while there was a prolonged kinetics (K) time and reductions in a-angle, MA, and CI. PLT ≤40×109/L, MA ≤357 mm, K time >4.2 minutes, a-angle ≤51.6, and CI ≤-5.9 could be used to predict spontaneous mucocutaneous/oronasal bleeding in patients with liver cirrhosis (all AUC >0.7), with positive predictive values of 82.4, 88.9, 81.0, 72.7, and 73.7, respectively, and negative predictive values of 68.3, 72.5, 73.0, 69.4, and 66.7, respectively. ConclusionPLT and the TEG parameters of K time, a-angle, MA, and CI can predict spontaneous bleeding caused by abnormal coagulation in liver cirrhosis, while conventional coagulation parameters prothrombin time and activated partial thromboplastin time cannot predict such bleeding, which provides a basis for the treatment of coagulation disorder and transfusion of blood components for patients with liver cirrhosis.