1.Value of serum amyloid A in patients with acute exacerbation of chronic pulmonary diseases
Yancong LI ; Jiesi ZHANG ; Chaowen GUO ; Jianzhi YUAN ; Fuyi LI
The Journal of Practical Medicine 2017;33(14):2349-2352
Objective To assess the value of serum amyloid A(SAA)in patients with acute exacerbation of chronic pulmonary diseases. Methods Seventy AECOPD patients were randomly chosen. The AECOPD patients were divided into bacterial infection induced group and non-bacterial infection induced group by sputum bacteria culture. Thirty five SCOPD patients were chosen as control group. General data was collected. Lung function ,chest X ray,blood routine,CRP,SAA,IL6 and PCT were deteced and compared in the 3 groups. The diagnostic value of SAA to distinguish bacterial infection induced AECOPD was estimated. Results SAA of both AECOPD sub-groups were significantly higher than that of healthy controls. SAA in infection group is higher that that in exacerba-tion group. In terms of ROC curve,AUC was 0.8682 for SAA to distinguish merging bacterial infection,and the cut-off value was 72.10 mg/L with sensitivity of 94.29% and specificity of 65.71%. Conclusion SAA increases in AECOPD patients,and more obviously in AECOPD patients with bacterial infection. SAA may be used as a reliable biomarker not only to distinguish AECOPD patients from SCOPD patients ,but also distinguish merging bacterial infection during AECOPD.
3. Study on handgrip strength of elderly ≥60 years old from longevity areas in China
Liqin SU ; Zhaoxue YIN ; Xiaochen WANG ; Yuebin LYU ; Wenhui SHI ; Juan ZHANG ; Jiesi LUO ; Xiaoming SHI
Chinese Journal of Preventive Medicine 2017;51(11):1007-1011
Objective:
To assess the status of handgrip strength of elderly population from longevity areas in China, and to analyze the correlative factors of handgrip strength of elderly people.
Methods:
Data from Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2012 was used, from which1 967 participants aged ≥60 years old with valid data of grip strength value from 8 Chinese longevity areas were included. Information on demographics characteristic, life style and health status was collected using questionnaires. The handgrip strength of both left and right hands were measured by grip dynamometer. The different characteristics of group of participants with different grip strength were compared and then analyzed by adopting the Cumulative odds Logistic regression model to identify main factors associated with hand grip strength.
Results:
The
4. Follow-up study of body mass index and risk of cognitive impairment among elderly adults aged ≥65 years old from longevity areas of China
Juan ZHANG ; Yuebin LYU ; Zhaoxue YIN ; Jiesi LUO ; Wenhui SHI ; Xiaoming SHI
Chinese Journal of Preventive Medicine 2017;51(11):1019-1023
Objective:
To discuss the relationship between body mass index (BMI) and cognitive impairment among elderly adults aged ≥65 years old from longevity areas of China.
Methods:
A total of 2 439 elderly adults from 8 longevity areas were included in our baseline survey by answering questionnaire and taking body measurements and blood biochemical examinations in 2012. In the follow-up study in 2014, we studied the cognitive impairment status among the 1 135 elderly adults aging ≥65 years old. Multivariate logistic regression model was used to analyze the relationship between BMI and cognitive impairment risk.
Results:
113 participants were defined as cognitive impairment, with a positive rate at 10.0%. The positive rate in group of underweight, normal weight, and overweight and obese elderly were 22.2% (51/230), 7.5% (47/629), 5.4% (15/276). The rate of cognitive impairment in groups of low BMI (<19.7 kg/m2), middle BMI (19.7-23.1 kg/m2) and high BMI (>23.1 kg/m2) were separately 17.7% (66/372), 7.1% (27/379) and 5.2% (20/384) (
5.Factors affecting the consumption of sugar-sweetened beverages among middle school students in eight counties of four provinces (municipality) in China
Hong ZHANG ; Jing WU ; Jixiang MA ; Jiesi LUO ; Yun FU ; Yanan WAN ; Yiying CHEN ; Zhongxi FU ; Zhaoxue YIN
Chinese Journal of Health Management 2019;13(3):231-236
Objective To explore the factors related to the consumption of sugar-sweetened beverages (SSB) among middle school students in four provinces (municipality) in China.Methods A total of 3 469 middle school students were recruited from the Children health cohort in eight counties within the four provinces (municipality).We collected information regarding demography,lifestyle,and family and school situation as well as the consumption frequency of SSB in the previous week.High SSB consumption was defined as "positive" if the frequency was once a day or more.Mean consumption time was calculated,and then logistic regressions were performed to explore the factors influencing SSB consumption.Results Prevalence of high SSB consumption was 11.18% among the subjects of the eight counties,and the consumption frequency of SSB was 0.21 times per day.Multivariate logistic regression analysis revealed that the following factors were associated with high consumption of SSB:higher grade,rural region,male gender,physical exercise,habit of eating snacks,eating out,and fast-food consumption (P<0.01).Factors influencing high SSB consumption were not completely equal between genders:physical exercise at school was associated with high SSB consumption only in female students (P<0.01),while higher grade and eating out in the past week were associated with high SSB consumption only in male students (P<0.05).Conclusion Factors associated with high SSB consumption among middle school students included grade,region,physical exercise at school,snack consumption,eating out,and fast-food consumption.These factors differed between genders.Intervention programs addressing these factors may be beneficial in reducing SSB consumption in middle school students.
6. Association between biomarkers and activities of daily living in the elderly ≥65 years old from longevity areas in China
Jiesi LUO ; Yuebin LYU ; Zhaoxue YIN ; Wenhui SHI ; Juan ZHANG ; Liqin SU ; Jianlong FANG ; Xiaoming SHI
Chinese Journal of Preventive Medicine 2017;51(11):1012-1018
Objective:
To explore the association between biomarkers and activities of daily living (ADL) in the elderly over 65 years old from longevity areas in China.
Methods:
A total of 2 439 people from 8 longevity areas were included in our baseline survey in 2012. Using questionnaires, body measurements, and blood biochemical examinations, information on demographics characteristic, life style, ADL, blood pressure and biomarkers were collected. Based on these six items of ADL (bathing, dressing, indoor activities, toileting, eating, bowel and bladder control), we constructed a dichotomous indicator for ADL. A respondent was defined as ADL disabled if any difficulty in one or more of the above six activities was reported. Information were collected in the follow-up in 2014 using the same questionnaires and examinations. We excluded information on the elderly who lacked ADL or biomarkers test results or with ADL disability at baseline study. Finally 938 elderly people over 65 years old were included in this analysis. Multivariate logistic regression model was used to analyze the influence factors of ADL disability.
Results:
During the 2-year follow-up, 100 (10.7%) participants developed into ADL disability, with a rate at 10.7%. Multivariate logistic regression analysis indicated that each year increase in age or each 1 mmHg (1 mmHg=0.133 kPa) increase in systolic blood pressure (SBP) would cause the risk of ADL disability to increase 9% or 1%, whose
7. A perspective cohort study on influence factors of survival outcome among the elderly aged ≥80 years old from longevity areas in China
Yuebin LYU ; Juan ZHANG ; Jiesi LUO ; Wenhui SHI ; Zhaoxue YIN ; Liqin SU ; Jianlong FANG ; Jiaonan WANG ; Xiaoming SHI
Chinese Journal of Preventive Medicine 2017;51(11):1028-1032
Objective:
To investigate the influence factors of survival outcome among elderly aged ≥80 years old.
Methods:
In baseline survey in 2009, 930 participants aged ≥80 years old were enrolled from 7 longevity areas, to collect the information of socioeconomic factors, life style, cognitive function, activities of daily living and diseases, as well as physical examination to test biomarkers of blood and urine. The survival status was followed up at 2012 and 2014 survey. Stepwise Cox proportional hazards models were used to screen influence factors of 5-year survival.
Results:
During 5 years of follow-up, 571 participants died, 133 participants were lost to follow up, and the all-cause mortality was 63.4%. In stepwise Cox proportional hazards models, male, unmarried, self-reported poor life quality, disability in daily life, cognitive impairment, cardiovascular and cerebrovascular diseases, chronic kidney diseases were risk factors for elderly survival outcome, with the