In 1970′s a prevailing hypothesis postulated herpes simplex virus in cervical cancer aetiology,but Hausen has made seminal observations that identify novel human papilloma viruses as key contributors to cervical cancer and hybridization technique of nucleic acid has proven it.After the discovery of human immunodeficiency virus(HIV) by Sinossi and Montagnier,they held the evolutional history of HIV.The article objectively evaluates the role in the discovery of HIV,played by Gallo.

Objective:To explore the effect of follow-up management of the use of insulin pumps outside hospital led by diabetes specialist nurses in type 2 diabetic patients.Methods:From April 2018 to March 2020, convenience sampling was used to select patients with type 2 diabetes who used insulin pumps in the First Affiliated Hospital of Xinxiang Medical University as the object. The patients ( n=104) enrolled from April 2018 to March 2019 were set as control group receiving conventional out-of-hospital follow-up management of insulin pump use, and patients ( n=152) enrolled from April 2019 to March 2020 were set as observation group adopted out-of-hospital follow-up management of insulin pump use led by diabetes specialist nurses, and the observation lasted for three months. The differences in fasting blood glucose, glycosylated hemoglobin, Scale of the Diabetes Self-Care Activities (SDSCA) score and the Exercise of Self-Care Agency Scale (ESCA) score, and insulin pump-related negative events were compared between the two groups of patients. Results:Before intervention, there was no significant difference in fasting blood glucose, glycosylated hemoglobin, SDSCA score, and ESCA score between the two groups ( P>0.05) . After intervention, the fasting blood glucose and glycosylated hemoglobin of observation group were lower than those of control group, and the scores of SDSCA and ESCA were higher than those of control group, and the differences were statistically significant ( P<0.05) . The fasting blood glucose and glycosylated hemoglobin of observation group after intervention were lower than those before intervention, and the scores of SDSCA and ESCA were higher than those before intervention, and the differences were statistically significant ( P<0.05) . In control group, there were 17, 23, and 14 cases of pipeline obstruction, hypoglycemia, injection site infection or induration respectively, and observation group had 8, 7, and 5 cases of pipeline obstruction, hypoglycemia, injection site infection or induration respectively; incidences of insulin pump-related negative events of control group and observation group were 51.92% and 13.16% respectively, and the difference was statistically significant ( P<0.05) . Conclusions:Follow-up management of out-of-hospital insulin pump use led by diabetes specialist nurses can increase the insulin adjustment self-efficacy of type 2 diabetic patients, effectively control blood glucose and glycosylated hemoglobin, improve self-behavior management and nursing ability, and reduce the occurrence of insulin pump-related negative events.