2.Processing and analysis of magnetoencephalographic data based on independent component analysis
Bin WANG ; Jieming MA ; Liming ZHANG
Chinese Journal of Tissue Engineering Research 2005;9(28):254-256
BACKGROUND: Induced response signal is blocked by the time of stimulation, showing some individual differences by special stimulation. Extracting induced response from magnetoencephalographic (MEG) data is important for understanding the function of human brain.OBJECTIVE: To apply independent component analysis (ICA) for overlapping multi-channel MEG signals so as to put forward a simple and effective method to analyze MEG data.DESIGN: A single sample analysis.SETTING: Electronic Engineering Department and Brain Scientific Research Center, Fudan University.PARTICIPANTS: The experiment was completed at Kansai Advanced Research Center of Japanese Communications Research Laboratory(CRL) in September 2002. One m ale healthy volunteer aged 23 years was selected from Tokyo Medical University of Japan, and other testees participated voluntarily.ed to process the 148-channel MEG data, especially for the extraction of eed independent components.MAIN OUTCOME MEASURES: Results of MEG data with ICA method.set. Most of the signal energy could be compressed in the first 30 principal components. In other words, the artifacts and evoked activations were exartifacts were detected and isolated to independent component 1, and the bursts should be detected in components 2, 3, 7 and 9. Beta bursts (13-30voked activation was obviously concentrated in component 5, which appeared a periodical waveform in response to the auditory stimulus.CONCLUSION: Interference source is separated from multi-channel MEG signals with ICA, then purified MEG data can be obtained. According to ICA, it is possible for research on cerebral nervous action to provide a new method by separating alpha wave, beta wave, eye movement artifacts and blinking. The auditory evoked response was successfully extracted from the multi-channel MEG signals using ICA.
3.Intraluminal brachytherapy in treatment of malignant obstructive jaundice
Yi CHENG ; Xiaolin WANG ; Jieming CHENG
Journal of Interventional Radiology 1994;0(04):-
Objective To study the practicability and preliminary effect of intraluminal brachytherapy in treatment of malignant obstructive jaundice.Methods Intraluminal brachytherapy was performed in 4 patients who had been treated with biliary stent implantation. Results No complications related to intraluminal brachytherapy had happened.One patient was followed up by means of CT,showing reduction in tumor size. Conclusion Intraluminal brachytherapy is a safe and effective method in treating malignant tumor causing obstructive jaundice.
6.Changes in plasma monocyte chemoattractant protein-1 in patients with acute coronary syndrome and patients with restenosis after angioplasty
Jie YU ; Jieming MAO ; Guang WANG
Chinese Journal of Tissue Engineering Research 2007;0(04):-
AIM: To observe acute coronary syndrome (ACS), including acute myocardial infarction (AMI), and unstable angina pectoris (UAP) and plasma monocyte chemoattractant protein-1 (MCP-1) in patients with restenosis after angioplasty, and compared with normal controls. METHODS: Sixty-eight patients were selected from the Department of Cardiology, Third Hospital Affiliated to Peking University between December 2005 and April 2006, including 30 patients with AMI, 20 patients with UAP and 16 patients with restenosis after angioplasty. Thirty healthy people were selected simultaneously to be the controls. All subjects knew and agreed with the items. The level of blood lipid was determined in all enrolled subjects: ① Blood sample was obtained from the elbow of patients with AMI immediately at hospitalization (2-12 hours from onset). ② Blood sample was obtained from patients of UAP group and patients of restenosis after angioplasty group immediately after the hospitalization (within 24 hours of onset). ③ Blood sample was obtained from fasting subjects of the normal control group in the morning. Blood sample was centrifuged, separated of the plasma and then frozen at -70 ℃. The level of plasma MCP-1 was determined with ELISA for statistical analysis. RESULTS: A total of 98 enrolled subjects were involved in the analysis of results, and no one withdrew from the study. Comparison in plasma MCP-1 among all groups: The plasma MCP-1 in ACS group, UAP group and restenosis after angioplasty group were (166.7?46.5,149.4?54.9,119.7?25.0,89.2?26.4) ng/L respectively, and it was significantly higher in ACS group, UAP group and restenosis after angioplasty group than that in the normal control group (F =21.27,P
7.The relationship among serum homocysteine, age, type of coronary heart disease and the branches of coronary arteriopathy
Zhen WANG ; Jingxuan GUO ; Yiming ZHAO ; Tiancheng WANG ; Jieming MAO
Chinese Journal of Geriatrics 2001;0(01):-
Objective To investigate the significance of homocysteine (Hcy) in pathogenesis of coronary heart disease (CHD) and the relationship among serum homocysteine , age, type of CHD and the branches of coronary arteriopathy. Methods In a cross sectional test, serum Hcy levels of 166 old cases (age≥60 years) and 161 non old cases(age
8.Microwave processing of Borax
Jieming ZOU ; Lisheng WANG ; Ruizhi WANG ; Guihua ZHAO
Chinese Traditional Patent Medicine 1992;0(01):-
AIM:To establish a new processing method for Borax with microwave technique. METHODS: A certain amount of Borax was placed into microwave oven and heated, and its weight loss was determined by electronic balance. The optimum processing parameters were obtained through orthogonal design. Water content of Calcined Borax was determined by far IR, microwave oven, and electric oven(at (400 ?C)),respectively. In addition, the stability of Calcined Borax was studied at room temperature. RESULTS: Calcined Borax will be available (within) 30 min with microwave treatment. The total water content can be determined by electric oven(at (400 ?C)). Calcined Borax should be powdered and packed as soosn as possible after processing. CONCLUSION: Microwave is a kind of excellent method for preparation of Calcined Borax in laboratory, with advantages of rapidness and simplicity.
9.Microwave processing of Alumen
Jieming ZOU ; Lisheng WANG ; Ruizhi WANG ; Guihua ZHAO ;
Chinese Traditional Patent Medicine 1992;0(07):-
AIM: To establish an effective and economical processing method for high quality of Calcinatum Alumen with microwave heating. METHODS: A certain amount of Alumen was placed into microwave oven and heated, and its weight was determined by electronic balance every one or five minutes. The quality (appearance, aqueous solubility, water content) of Calcined Alum by microwave was compared with those of products prepared by traditional method, far IR, and electric oven. Moreover, the stability of Calcined Alum in several kinds of package were investigated at room temperature. RESULTS: The microwave for the processing of Alumen has the advantage of rapidness, low cost, and less water content, and its product could be dissolved completely in water. CONCLUSION: Microwave is a practical technique for Alumen processing.
10.Development and in vitro study of miniature implantable axial flow blood pump
Yuxuan WANG ; Jieming ZHANG ; Chao SHI ; Xiaocheng LIU
Journal of Chinese Physician 2009;11(6):730-733
Objective The research of impeller blood pump has been the key point in cardiac surgery and biomedical engineering fields in recent years. To investigate hydrodynamies of self researched and developed mini axial flow pump, parameters of pump were tested on a homemade mimic vitro platform. Methods Hydrodynamics tests were performed in vitro mimic circulation, water and 30% glycerin in water as respeetive circulatory mediator to simulate blood. Results Flow rates can reach 6. 19L/min and 5.08L/min respectively in water and 30% glycerin, when rotation speed was 13000rpm and pressure was 100mmHg. Conclusion Axial flow blood pump has good hydrodynamics to substitute for left ventricle, whieh can meet the demand of assisted circulation in congestive heart failure patients.