Objective To investigate the clinical therapeutic effectiveness of fingering expansion anus with the application of acupoint treatment to patients with severe craniocerebral injury. Methods Ninety-one patients with constipation in our hospital from May 2013 - May 2015 were randomized into the control group ( n = 45 ) and the observation group ( n = 46 ) . All patients were implemented with routine care of constipation . Based on those regular treatments , the patients in the observation group received the treatment of anus expansion with fingers accompanying plus acupoint treatment with rhubarb powder for three days. The short-term therapeutic effectiveness was evaluated after 3 days of treatment while the long-term therapeutic effectiveness was analyzed 2 weeks later. Results After performing this treatment for 3 days and 2 weeks, the overall clinical symptoms of constipation in the treatment group was significantly lower than those of in the control group (P<0.05). Both the long-term therapeutic effectiveness after treatment two weeks and the short-term therapeutic effectiveness of the observation group were significantly better than those of the control group (P<0.05). Conclusions Anus expansion anus with fingers together with acupoint application in treating constipation is convenient and accessible. Its high effectiveness and limited side-effects can be the best evldence for its unlimited potential of clinical popularization and application.