Objective To study the value of routine laboratory examinations, symptoms and soluble IL-2 receptor (sIL-2R) in the flare-prediction on systemic lupus erythematosus(SLE). Methods A prospective study was performed in 106 outpatients with SLE and the patients′ conditions were assessed according to Systemic Lupus Erythematosus Disease Activity Index(SLEDAI). Patients were asked to visit at no longer than 3-month interval. All patients were followed-up for 6 to 18 months. At each visit, laboratory examinations, symptoms, disease activity, as well as the changes in the treatment were recorded according to the protocol. The values of these parameters in flare-prediction were comprehensively assessed based on their frequency and time respectively when they became abnormal before the disease flare. Results Among the 106 patients, the disease activity of 67 cases were in remission and satisfied the prospective study criteria of the SLE flare. Thirty-one flares in 29 patients were observed. The frequency of flare was 0.44/patient/year. Comprehensively the most valuable predictor of those parameters was anti-dsDNA antibody, followed by complement components, sIL-2R, erythrocyte sedimentation rate(ESR), complete blood count, urine analysis, fatigue, mucous membrane ulceration, new rashes and alopecia. C3 was a better predictor for SLE flares than that of C4 and CH50. Conclusions The flares of SLE could be predicted. Early intervention will help to prevent patients from flare.

Thirty-one cases of infant respiratory tract infection were treated by no-pain health-care Tuina plus medicated bath. Since the therapeutic effects were satisfactory, so parents and infants are willing to accept.

Acupuncture Therapy ; Adult ; Diarrhea ; therapy ; Humans ; Male

Acupuncture Therapy ; Adult ; Fatigue ; therapy ; Female ; Humans ; Seasons ; Sleep Wake Disorders ; therapy

In this paper, we studied the effect of total flavones of Hippophae rhamnoides L (TFH) on beating and transmembrane potential of cultured sucking rat cardiac cell. The results indicated that cellular beating rate and beating amplitude were significantly reduced, the action potential duration of 50% and 90% repolarization was sbortened, the slope of phase 4 depolarization was decreased, and other parameters of the action potential showed no significant change. In addition, we also observed that TFH could make the spontaneous abnormal beating of cell change into regular beating. These findings suggested that the mechanism of TFH on cultured cardiac cell might have some relation to antagonizing inward flow of Ca~(2+) and aocelerating the move of k' outward.

Objective To investigate the changes of disease activity and clinical significance in the course of treatment in patients with SLE.Method 286 cases of SLE were reviewed and compared the changes of SLEDAI scores in different disease duration.Results The SLEDAI scores of patients whose first treatment courses less than 1 month and 1 to 3 months were significantly lower than those patients whose were 4 to 6 months and more than 6 months. After treatment for 2 months to 3 years, the SLEDAI scores were not correlated with cumulated dosage of corticosteroids.Conclusions For the patients of short first treatment course, the treatment could relieve SLE disease activity rapidly and effectively to some extent; while for the patients whose first treatment courses were relatively long ,the relif of disease activity was relatively slow. After treatment for 2 to 3 months, the disease of SLE patients was more active than other periods, and it was inclined to produce visceral damage. As mentioned above ,we should pay attention to this phenomenon.

Objective To investigate the unusual CT features of pulmonary sclerosing hemangioma (SH). Methods Clinical and CT features of 25 patients of pulmonary SH proved with pathology were reviewed, among which 15 patients underwent plain and enhanced CT scan, 10 underwent only plain CT scan. Results Solitary nodules (20/25, 80.00%) and solitary mass (5/25, 20.00%) were found with CT. CT features included slight lobulation (6/25, 24.00%), calcification (6/25, 24.00%), ground glass opacity (2/25, 8.00%), emphysema (1/25, 4.00%), endobrochial variant (1/25, 4.00%), short speculation (1/25, 4.00%) and vascular bundle (2/25, 8.00%). Slight or remarkable enhancement was noticed in all 15 patients underwent contrast enhanced CT. Conclusion CT can reveal features and unusual manifestations of pulmonary SH, and is helpful to the diagnosis of pulmonary SH.

Purpose To summarize the CT features and clinical characteristics of atypical primary fallopian tube cancer (PCFT) and ovarian cystadenocarcinoma (OCA), in order to improved the diagnosis. Materials and Methods CT findings and clinical data of 12 patients with atypical PCFT (PCFT group) and 20 patients with OCA (OCA group) were retrospectively studied. All patients were confirmed by pathology. Serum CA125 level, clinical characteristics and CT features of two groups were compared. Results Serum CA125 level of PCFT group and OCA group were (486.13±23.89) U/ml and (1606.94±62.86) U/ml, respectively. There was statistic difference between the two groups (P<0.01). There was significant differences on vaginal bleeding and vaginal discharge between the two groups (P<0.01). There were 4 cases with solid mass, 8 cases with cystic solid mass in PCFT group. And in OCA group, 16 cases with cystic solid mass and 4 cases with cystic mass were revealed, which showed statistic differences between the two groups (P<0.05). Some other findings also showed statistic differences including the diameter of ovarian vein on the affected side, the diameter of the round ligament of uterus on the affected side, tumor volume, and CT values of the mass in venous phase and delay phase (P<0.05 or P<0.01). However, there were no statistic significance in the size of metastatic lymph nodes, the mean CT value of the mass on plain scan and in the arterial phase (P>0.05). Conclusion Clinical findings of serum CA125 level, vaginal bleeding, and vaginal discharge combine with imaging findings of diameter of the ovarian vein in the affected side, diameter of ipsilateral round ligament of uterus, tumor volume, CT values of the mass in venous and delay phase would be the key points for differential diagnosis of PCFT and OCA.

Objective To evaluate the recovery and hemedynamics of total intravenous anaesthesia (TIVA) with propofol and remifentanil. Methods Thirty ASA Ⅰ - Ⅱ patients undergoing hperoscopic oper-ation were randomly divided into the TIVA group(group A,n=15) and the combined intravenous with inhala-tion anaesthesia greup(group B,n=15). Anaesthesia was induced in the same manner in both greups:Midazo-lam 0.05mg/kg,vecurium 0.1mg/kg,propofol 1.5mg/kg and remifentanil 1.5 μg/kg.Remifentanil was infused 2.5 μg/ml) in group A or with sevoflurane( 1.3% end-tidal) in group B to maintain anaesthesia. With termi-nation of surgery,anaesthetic delivery was discontinued simuhaneously.Bp,HR at all stages and recovery profiles were recorded. Results (1)Between before inflation and after inflation or between at the end of op-eration and the basic values in group A,there were no significant differences in Bp,HR. (2) Times from stop-ping administration of anaesthetics until full spontaneous respiration and eye opening were similar for two groups.Time for trachcal extubation was significantly less in the group A than group B. (3)The rates of post-operative nausea or vomiting were similar. Conclusion The application of TIVA with propefol and remifen-tanil is associated with better hemodynamic stability and better recovery profile as compared to the combined intravenous with inhalation anaesthesia.

Objective To investigate the clinical effects of Losartan on hemorrheology and left heart function in essential hypertensive patients.Methods 43 essential hypertensive patients were treated with Losartan,50 ms/d～100 ms/d for twelve to seventeen months.20 essential hypertensive patients were treated with Fu Fang Jiang Ya Pian as control group.Then the changes of hemorrheology indexes and left heart function were tested in both groups.Results After the treatment with Losartan the blood pressure reduced effectively(P＜0.001),the whole blood low shear rate hyperviacoSity(ηb),plasma viscosity,AI,whole blood low shear rate reduced viscosity,erythrocyte electrophoresis,Fib reduced obviously(P＜0.01),but the control group had not statistical significance(P＞0.05)before and after treatment.The whole blood high shear rate hyperviscesity,whole blood high shear rate reduced viscosity,Hct,RRI reduced too(P＞0.05),but there was no statistical significance.LVM(P＜0.01)and LVMI(P＜0.05)were obviously reduced,E/A was increased(P＜0.01),IRT(P＜0.05)was shorten (P＜0.05),while the cardiac diastole function improved effectively.The significant differences were not observed in the control group pre and pest treatment(P＞0.05).Condusion Losartan can effectively reduce blood pressure.At the same time,it improves RBC deformation capability,reduce erythrecyte aggregation,Fib,Hct of essential hypertensive patients,and reduce blood viscosity.Losartan can also reduce myocardial hypertrophy,heart weight,and improve heart function.