Adolescent ; Humans ; Lung ; diagnostic imaging ; pathology ; Lung Neoplasms ; diagnostic imaging ; pathology ; surgery ; Male ; Papilloma ; diagnostic imaging ; pathology ; surgery ; Pneumonectomy ; methods ; Tomography, X-Ray Computed

Acupuncture Therapy ; Adult ; Diarrhea ; therapy ; Humans ; Male

Acupuncture Therapy ; Adult ; Fatigue ; therapy ; Female ; Humans ; Seasons ; Sleep Wake Disorders ; therapy

Objective To comprehend the etiology and the clinical characteristics of hypereosinophilia.Methods The clinical data of 53 patients with hypereosinophilia admitted to Peking Union Medical College Hospital from November 1992 to February 2005 were analyzed.Results The causes of reactive hypereosinophilia included allergic diseases,infections,connective tissue diseases,malignant diseases,lung diseases,eosinophilic gastroenteritis.idiopathic hypereosinophilic syndrome had longer course of disease;more organ involved than reactive causes.The incidence of lymph node enlargement,spleen enlargement and thrombus was higher than the reactive.IHES had higher level of white blood cell count,absolute eosinophilic count,IgG and CRP.Conclusion The etiology and clinical characteristics of hypereosinophilia are various,so the differential diagnosis of hypereosinophilia is very important.

Disrupted pancreatic ?-cell function and decreased ?-cell number are two of the main causes of type 2 diabetes mellitus.Recent studies have indicated that autophagy plays an important role in protecting pancreatic ?-cell and in maintaining the structure,number,and secretive function of pancreatic ?-cell.Although autophagy has been a focus of study in recent years,including areas such as tumor,neural diseases and aging,but its relationship with pancreatic ?-cell was not included.In this paper we review the concept of autophagy and its role in maintaining the normal function of pancreatic ?-cells.

AIDS has become a devastating disease facing human around the world.Western medicine can reduce blood HIV load,thereby promoting recovery of immune function. With the extensive application of HAART,many unsolvable problems appear.There is much experience in treatment for infectious diseases in TCM.So,it is necessary and feasible to treat AIDS with TCM.Combination of Chinese and western medicine will achieve complementary advantages and may be a new model for AIDS treatment.Many researchers carry out study on it,but there are still a lot to do to improve the drawbacks.

In order to evaluate appropriately the role of lipid metabolism by the refined konjac meal (RKM), a new source of dietary fiber, the effects of RKM on the level of serum and liver lipids, hepatic histopathology and on the composition and output of fecal bile acids in comparison with pectin, algin and agar were studied.The RKM contained about 75-80% of glucomannan. All four kinds of dietary fiber "were given at a level of 5% in the diet to the young male Wistar rats fed on a lipid-rich diet containing 5% lard, 1% cholesterol and 0.25% chplate. The control group was fed on a lipid-rich diet alone withput fiber. The normal group was fed on a basal diet without extra lipid added. Feeding period was 9 weeks.The results obtained were as follows;1)All the dietary fibers tested have the similar effects on serum lipid composition. At the end of 2-week of the experiment, the serum total cholesterol levels of the four experimental groups were only 62% to 75% of that of the control group, and at the end of 7-week they were lowered to the same level of the normal group. The level of the triglyceride in serum did not change in all groups during the experiment.2)Relative liver weights were lower in four experimental groups than in control group. Hepatic hisiopathological examinations showed lipotropic effect in RKM, pectin and algin groups. Both of the above effects appeared most significantly in RKM group. The concentrations of total cholesterol and triglyceride in liver in RKM group were lower than those in control group as well as other three experimental groups.3)No harmful effects on the intake of food and growing of rats were found when feeding these four kinds of dietary fiber at the level of 5%.4)The daily output of fecal bile acids (CDCA + GDCA) was significantly increased in four experimental groups.The increase of fecal output of bile acids, especially CDCA, may be one of the mechanisms of hypocholesterola-emic effect of dietary fibers.It could be concluded that RKM has the same significant hypocholestero-lemic effect as the pectin, algin and agar, but its lipotropic effect is more potent.

Objective To observe the efficacy of methylprednisolone stosstherapy of the IgA nephropathy complicated with partial crescenties formation and effects of this therapy on the urine protein output and renal function.Methods 93 patients of IgA nephropathy complicated with partial crescenties formation were identified by renal biopsy and diagnosed according to the WHO diagnostic criteria in 1982 formulation.The patients were randomly divided into two groups:the control and the treating groups.The control group was treated with oral prednisolone (1mg/Kg/day) plus oral cyclophosphamide(2mg?kg -1 ?d -1 ),while the treating group was administered, on the basis of the therapeutic scheme of the control group,with methylprednisolone 0 5～1 0g(20mg?Kg -1 ?d -1 ) in normal saline solution intravenously by drip,for 8 weeks,The degree of puffiness,BP and 24h urine volume were observed in both groups befoue and after the treatment. The 24h urine protein quantitative determination,urine RBC count(uRBC),urine creatinine,blood creatinine(Cr),blood urea nitrogen(BUN),serum albumin (ALB) and the endogenous creatinine clearance rate (Ccr) were also tested.The side effects in two groups were observed at the same time.Results The urine protein output amounts, urine RBC count,blood Cr and BUN were significantly decreased (P

The rashness in research as reflected in the initial misidentification of the pathogen of SARS is of great enlightening and warning significance to scientific and technical workers in the medical field. In order to effec-tively reduce errors in the clinical diagnosis of SARS, succeed in obtaining reliable methods for its specific diagnosis, and strive for a genuine victory in the fight against it, it is imperative to vigorously uphold the scientific spirit of adher-ing to truths and defying authorities and promote the style of doing things in a rigorous, realistic, accurate, persistent and down-to-earth manner. Rashness must be avoided by all means.

Objective To study the value of routine laboratory examinations, symptoms and soluble IL-2 receptor (sIL-2R) in the flare-prediction on systemic lupus erythematosus(SLE). Methods A prospective study was performed in 106 outpatients with SLE and the patients′ conditions were assessed according to Systemic Lupus Erythematosus Disease Activity Index(SLEDAI). Patients were asked to visit at no longer than 3-month interval. All patients were followed-up for 6 to 18 months. At each visit, laboratory examinations, symptoms, disease activity, as well as the changes in the treatment were recorded according to the protocol. The values of these parameters in flare-prediction were comprehensively assessed based on their frequency and time respectively when they became abnormal before the disease flare. Results Among the 106 patients, the disease activity of 67 cases were in remission and satisfied the prospective study criteria of the SLE flare. Thirty-one flares in 29 patients were observed. The frequency of flare was 0.44/patient/year. Comprehensively the most valuable predictor of those parameters was anti-dsDNA antibody, followed by complement components, sIL-2R, erythrocyte sedimentation rate(ESR), complete blood count, urine analysis, fatigue, mucous membrane ulceration, new rashes and alopecia. C3 was a better predictor for SLE flares than that of C4 and CH50. Conclusions The flares of SLE could be predicted. Early intervention will help to prevent patients from flare.