BACKGROUND:Zirconia is considered to be one ofthe promising prosthodontics materials because of its high strength, high hardness, excelent wear resistance and excelent corrosion resistance. However, the development of zirconia is hindered owing to the uncertainty in long-term stability of zirconiaal-ceramic crowns such as the cracking (chipping) of veneering porcelain and deterioration of mechanical properties of zirconia dental crowns under intraoral conditions.
OBJECTIVE:To summarize the preparation of zirconia bioceramic and its application progress in the field of prosthodontics.
METHODS:The properties, crystal structure, preparation and use of zirconia in prosthodontics were reviewed. Reasons that affected the stability of zirconia were also discussed. The future development of zirconia was forecasted.
RESULTS AND CONCLUSION:Preparation of zirconia bioceramics involves the folowing aspects:powder synthesis, biscuit molding, and ceramic sintering.To improvethe istability of zirconia al-ceramic crowns,we optimize the preparation of zirconia powder topromotethe purity, mechanical properties, biological properties and stability. Furthermore, it is necessary to explore the effects of crystal nucleation, growth, second phase and grain size on crystal stability and biomechanical propertiesof thetooth abutment, as wel astoconduct an in-depth theoretical analysis on the effect oftooth abutmentand lattice matching of porcelain crowns on the interface.

Objective To understand the status of stroke patients' perceived control and healthrelated quality of life,and to analyze the effect of perceived control on stroke patients' depression and health-related quality of life.Methods By convenience sampling,264 stroke patients were chosen to complete the questionnaire survey,Perceived Control Questionnaire,Hamilton Depression Scale and ShortForm Health Survey Scale-2.Results The score of patient's perceived control and health-related quality of life were (18.21±2.74),(46.62±11.56) points respectively.The perceived control had a negative correlation with the depression (r=-0.32,P ＜ 0.05),had a weak positive correlation with the body health (r=0.05,P ＜0.05),and had a positive correlation with the mental health of health-related quality of life (r=0.29,P ＜0.05),depression was negatively correlated with health-related quality of life of the body health,mental health (r=-0.26,-0.28,P ＜ 0.05).Conclusions Medical personal should improve the level of stroke patients' perceived control through various methods,to reduce depression and improve health related quality of life.

Objective To understand the status of colleague support and colleague solidarity of nurses,and explore the relationship between colleague support and colleague solidarity.Methods A total of 231 nurses from Zhengzhou City were chosen using convenience sampling method to complete the questionnaire survey about colleague support and colleague sohdarity.Results The nurses' colleague support scored (76.34±2.75) totally and colleague solidarity scored (64.63±4.25) totally.In dimensions of nurses' perception of colleague support,head nurse support,support result,cooperation,sympathy establishment,awareness increasing were positively correlated with emotional unity dimension of colleague solidarity (r=0.32,0.26,0.27,0.30,0.28,all P＜ 0.05);head nurse support,support result,cooperation,awareness increasing,goal setting,action projects were positively correlated with academic unity dimension of colleague solidarity (r=0.30,0.28,0.25,0.29,0.27,0.26,all P ＜ 0.05);head nurse support,support result,cooperation,awareness increasing,action projects and process management were negatively correlated with negative views of colleague solidarity (r=-0.31,-0.27,-0.30,-0.23,-0.24,-0.27,all P ＜ 0.05).Conclusions Improving the nurse colleague-peer support can improve degree of colleague solidarity.

Objective To compare the differences in behavior characteristics among SHR, WKY and SD rat models of attention deficit/hyperactivity disorder (ADHD), and explore an ideal control model of SHR rats.Methods Using open field test to analyze the rat movement distance, speed, wearing numbers and the number of grooming to evaluate the spontaneous movement in SHR, WKY and SD rats.Using the Morris water maze to test the learning and memory ability among the three rat groups.Results The result of open field test showed that the SHR rats had significantly increased (P< 0.01) total amount of exercise, average speed and wearing numbers than WKY and SD rats.Compared with the WKY rats, SD rats had a significantly higher movement distance (P< 0.01), slightly higher movement speed and wearing number (P< 0.05).In the Morris water maze hidden platform period test, the SD rats had a significantly longer latency than the SHR rats (P< 0.05).SD rats showed longer latency distance on the first, third and fourth days of training, as compared with the SHR rats (P< 0.05 or P< 0.01).Compared with the WKY group, SD rats showed a shorter latency distance in each training time (P< 0.05 or P< 0.01).In the probe trial period, the SD rats showed shorter time and distance ratio to the target quadrant than SHR rats (P< 0.05), while significantly longer than the WKY rats (P< 0.05 or P< 0.01).Conclusions There are significant behavioral differences between SHR and WKY rats, showing certain disadvantages in comparison of the two types of rats.To add SD rats as a control group for SHR rats can improve the comparability of behavior characteristics of SHR rats, and to get more objective evaluation of the behavior characteristics of SHR rats.

This article shows a new design of telerehabilitation system for balance function assessment and training in our laboratory. The system is based on C/S network architecture, and realizes the telecommunication through socket network communication technology. It implements the teletransmission of training data and assessment report of sit-down and stand-up, online communication between doctors and patients, and doctors'management of patient information. This system realizes remote evaluation and telerehabilitation of patients, and brings great convenience for the patients.
Humans ; Physical Therapy Modalities ; Postural Balance ; Rehabilitation ; Telecommunications

Objective To introduce an improved extraction method of prefrontal cortical and striatal synaptosomes from SHR rat. Methods Synaptosomes were prepared from SHR rat brain tissue by Percoll density gradient centrifugation.Transmission electron microscopy was used to assess the morphology and structural integrity of the synaptosomes.Results The obtained synaptosomes showed oval structures surrounded by an intact membrane.Presynaptic components contained one or more mitochondria and a large number of synaptic vesicles.The synaptic clefts were clearly visible, and prominent part of the characteristic compact structure was clear, complete and with higher electron-density. The synaptosome presynaptic membrane, synaptic cleft, and postsynaptic membrane were well preserved, and the synaptosomes were densely distributed, showing typical morphological characteristics of synaptosomes.Conclusions The results of our study improved the traditional preparation method and provide a less time-consuming, highly productive protocol for preparation of structurally typical and intact synaptosomes, suitable for further research on neuroscience and neurological diseases.

Objective:To analyze the immunocontraceptive efficacy of CZP3 DNA vaccine by electric pulse stimulating and the correlation between antibody level and antifertility. Methods: The mice were immunized with 5, 10, 20 and 50 μg DNA vaccine pcDNA3. 0-CZP3 respectively and were stimulated at leg muscle by electric pulse. Detect the antibody level of each mice group and the highest antibody titer by ELISA. After mated with male mice for three weeks,calculated infertility rate of mice,the average litter size of each immune group and did statistical analysis. Results:Compared with the intramuscular injection alone,the electric pulse stimulation could increase serum antibody titers of mice significantly, the antibody titer of 50 μg group which was stimulated by electric pulse reached 1∶4 000. Moreover,the infertility of the mice increased and the mice average litter size reduced along with the increase of CZP3 antibody level significantly. Statistical analysis showed that the antibody level and the average litter size had a negative correlation. Conclusion:The electric pulse stimulation can improve the immune level and reduce the fertility efficiency of mice significantly,therefore establishes a foundation for further application of CZP3 DNA vaccine in stray dog contraception.

Objective To discuss the research status of TCM therapy for ADHD in China in recent ten years; To provide references for clinical workers. Methods Clinical research papers about TCM therapy for ADHD in CNKI, VIP, and CBM from 1st January 2005 to 1st April 2015 were retrieved. Metrology analysis was conducted from the aspects of publication time, diagnostic criteria, contrasted medicine, and types and features of TCM therapy. Results By eliminating duplication literature, 670 papers were screened out. After the screening of exclusion criteria, 148 papers were included. DSM-Ⅳ and CCMD-3 were the most commonly used diagnostic criteria in the 148 papers; internal therapy was the main therapy in TCM therapy; decoction was the main dosage form; liver-kidney yin deficiency syndrome and heart-liver fire syndrome were the main patterns of syndrome; Acori Tatarinowii Rhizoma, Rehmanniae Radix Praeparata and other 19 Chinese medicinal herbs were the main Chinese mateia medica; Xiaoer Zhili Syrup was the most commonly used Chinese patent medicine; acupuncture and moxibustion and auricular point therapy were the main external therapy, and external combined with internal therapy had the best efficacy. Conclusion TCM therapy for ADHD is with high effectiveness. External combined with internal therapy has the best efficacy.

The paper introduces the innovative service modes of the hospital tibrary under the Intemet +environment,including the mode of innovative service for medical personnel on one hand,namely medical personnel oriented mobile information service,embedded service,personalized service and fragmented service and the mode of innovative service for patients on the other hand,including new technologies,humanization,etc..

Autoimmune encephalitis is a kind of inflammatory disease of central nervous system caused by abnormal immune response of body immune system to neuronal antigen,and is generally considered to be reversible encephalitis caused by noninfectious factors.Its characteristic manifestations include acute and subacute onset of cognitive dysfunction,epilepsy and mental disorder.With the discovery of related antibodies,summaries of clinical syndrome and application of new functional imaging instruments,the diagnosis of autoimmune encephalitis is increasingly standardized.The priority treatment of autoimmune encephalitis is immunomodulatory therapy,including glucocorticoid,immunoglobulin,plasma exchange and immunosuppressant.The other treatments could be the related tumor resection,electroshock therapy,etc.The symptoms in most patients can get substantial relief with active treatment.The present paper would focus on the research progress in treatment of autoimmune encephalitis.