1.Analysis on the correlation of coagulation index of peripheral blood and clinical stage in patients with gastric carcinoma
Clinical Medicine of China 2012;28(3):290-294
Objective To explore the relationship among the changes of five coagulation indexes and clinical stage,metastasis in pre-operative patients with gastric carcinoma,and to investigate the coagulation in patients with different clinical stages and its clinical significance.Methods Eight hundred and sixty-eight gastric carcinoma patients( carcinoma group) who were firstly diagnosed and 213 patients ( control group) who were diagnosed as inguinal hernia in the same hospital during the same period were enrolled.Levels of rothrombin time (PT),activated partial thromboplastin rime (APTT),fibrinogen (FBG),plasma thrombin time (TT) and platelet count (PLT)were observed and compared in these two groups.Results (1)Compared with health control group,PT( [ 11.51 ± 1.21 ] s vs [ 11.27 ± 0.91 ] s,t =- 3.226,P < 0.01 ),FBG( [ 3010.0 ±470.4] mg/L vs [ 2307.1 ± 651.8 ] mg/L,t =- 4.240,P < 0.01 ) and PLT ( 238.57 ± 78.50 ) x 109/L vs (206.79 ±61.01 ) x 109/L,t =-5.514,P <0.01 )were significantly increased in gastric carcinoma group.(2)PT,FBG and PLT were significantly different between control group and different clinical stages of gastric carcinoma group ( P < 0.05 or P < 0.01 ).The levels of APTF,TT exhibited no significant difference between control group and different clinical stages of gastric carcinoma group ( P > 0.05 ).( 3 ) Compared with gastric carcinoma without metastasis group,preoperative blood PT extended significantly ([ 11.41 ± 0.99] s vs [ 11.57 ± 1.32 ]s,t =- 2.095,P < 0.05 ),FBG concentration increased significantly ( [ 2639.1 ± 748.6 ] mg/Lvs [ 3233.2 ± 591.60 ] mg/L,t =- 2.307,P < 0.05 ) and PLT count increased significantly ( [ 224.02 ±76.94] x 109/L vs [ 247.32 ± 78.37 ] x 109/L,t =- 4.299,P < 0.01 ) in gastric carcinoma with metastasis group.(4) Correlation analysis on four coagulation and PLT count with clinical stage:PT ( r =0.071,P < 0.05 ),FBG ( r =0.271,P < 0.01 ) and PLT( r =0.166,P < 0.01 ) were positively correlated with clinical stage of gastric carcinoma and TT( r =- 0.077,P < 0.05 ) was negatively correlated with clinical stage,among the total,the correlation coefficient of FBS with clinical stage was maximum.Conclusion Most patients with gastric cancer present state of blood coagulation and bleeding tendency,particularly in advanced gastric cancer,and with increased clinical stage of gastric cancer,some coagulation indicators showing a rising trend.Detection of coagulation index indirectly indicates the incidence,invasion and metastasis of gastric carcinoma.
2.Clinical application on 20 cases of mild hypothermia on patients with severe brain injury
Chinese Journal of Primary Medicine and Pharmacy 2006;0(12):-
Objective To evaluate clinical effect of mild hypothermia on patients with severe brain injury.Methods 40 patients with severe brain injury were randomly divided into hypothermic group(n=20) and control group(n=20).Their excellence rates cvere compared.Results The total excellence rate of treatment group was 80% and that of control group was 50%,the former was significantly higher than the latter.Conclusion Mild hypothermia can improve the outcome of patients with severe brain injury.
3.Effect of different acupoint prescriptions on prevention and treatment of stress gastric ulcer.
Zhao-Hui WANG ; Jiao-Jiao ZHANG ; Fu-Chun WANG
Chinese Acupuncture & Moxibustion 2014;34(2):149-151
OBJECTIVETo investigate the effects of different acupoint combination on prevention and treatment of stress gastric ulcer and to search for a better acupoint combination.
METHODSThe theoretical basis and experimental research on treatment of stomach diseases with the combination of he-(sea) points and front-mu points as well as back-shu points and front-mu points are analyzed in this article.
RESULTSThe combination of he-sea points and front-mu points is suitable to be applied on acute diseases, febrile diseases and diseases of fu organs. While the combination of back-shu points and front-mu points is more applicable on chronic gastric diseases.
CONCLUSIONIt is proved that the combination of he-sea point (Zusanli ST 36) and front-mu point (Zhongwan CV 12) has reliable effect on prevention and treatment of stress gastric ulcer.
Acupuncture Points ; Acupuncture Therapy ; Adult ; Aged ; Humans ; Male ; Stomach Ulcer ; physiopathology ; therapy
5.Qualitative research on status of residents' living condition in Third Grade Class A hospitals in Beijing
Guangyuan JIAO ; Meng ZHAO ; Jian ZHANG
Chinese Journal of Medical Education Research 2017;16(2):189-193
Objective By exploring the state of residents' living condition, it is helpful to promote the living condition of residents and improve the quality of medical services. Methods A qualitative re-search was conducted on 13 residents in 4 hospitals in Beijing by depth interview during April to May 2016, and the data were collected and analyzed by using Colaizzi seven step method. Results In terms of work, the residents had specific work, and the interpersonal relationship was more harmonious. In learning, residents were able to take the initiative to learn, and hoped to get more help in scientific research. In life, residents faced multiple pressures from the economy and the family. In the subjective cognition, the cogni-tion of resident was rational and objective. Conclusion The residents' work shows a heavy workload, and while working the residents need to take the study and the life pressure into account. And the residents can rationally recognize their role. To improve the living status of the resident physician, we need to integrate multiple forces, to promote the integration of live doctors into the hospital culture, and enhance their sense of existence. We also need to improve the construction of the system and improve the protection of live training physicians to enhance their sense of security. Most important of all, the whole society should pay more attention to the living condition of the residents and enhance their sense of access.
6.Practice of research laboratories management in the medical university
Rujuan JIAO ; Yuanyuan ZHAO ; Jinlu ZHANG
Chinese Journal of Hospital Administration 2013;(6):469-471
Well-designed operation and management system of research laboratories is essential for scientific innovations and talent training.The reform of the traditional laboratory management to encourage science innovation and development is key to promoting the laboratories to develop in scale,level and efficiency.On the basis of profiling traditional lab management and its setbacks,the paper described the management mode and operation mechanism of Capital Medical University.Such mode and mechanism feature lab project Principal Investigation responsible system,and shared platform for large equipments and services.The paper also discussed lab operation and management system for universities at large.
7.Research progress on surface modification of titanium and titanium alloys by ion implantation
Jiao FANG ; Yanmin ZHOU ; Jinghui ZHAO
Journal of Practical Stomatology 2014;(4):560-563
Ionimplantationtechniqueisamethodthatprocessingthematerialsurfacesinordertochangetheirsurfacechemical,physical and mechanical properties in vacuum environment.Titanium and titanium alloys modified by different types of ions can change their surface properties and characteristics,thereby improving the osseointegration and antibacterial properties of titanium implant.This review summarizes the researches of titanium implant surface modified by different ions implanting.
8.The Ultrastructural Observations of the Normal Anterior Cruciate Ligament
Chen JIAO ; Yinafang AO ; Xinrong ZHAO
Chinese Journal of Sports Medicine 2010;(1):56-58
Objective To study the ultrastructure of the anterior cruciate ligament.Methods Specimens were procured from seven patients with arthroscopy and observed under scanning and transmission electron microscope. Results Fibrils of normal anterior cruciate ligament arrayed in compact parallel form with waviness.Connecting fibers existed between fibrils.Diameters of fibrils were different with range of 30nm to 60nm mostly.Fibroblasts were distributed along with the fibrils.Active cells excrete filamentous collagen fibrils.Conclusion The ultrastructure of the anterior cruciate ligament was correlated with its function status.Mature fibroblasts existed in the ligament.
9.Analysis on Present Situation of ADR of Traditional Chinese Medicine for External Use
Jiao ZHAO ; Huizong ZHANG ; Guoxin LI
Chinese Journal of Information on Traditional Chinese Medicine 2015;(4):132-136
This article reviewed occurrence of ADR of clinical external use of 50 Chinese medicinal herbs, such as Verbascum Thapsus, Ranunculus Sceleratus, and Euphorbia Esula. It summarized from foundation, property, efficacy, clinical manifestation, and classification of ADR, and discussed early warning ways of ADR from TCM external use, with a purpose to provide references for TCM reasonable medication.
10.Evaluation of the application effect of cleaning packaging of surgical medical apparatus and instruments in sterilization and supply center of hospital
Liling JIAO ; Wenhong LIU ; Junxia ZHAO
Chinese Journal of Practical Nursing 2012;28(14):1-3
Objective To investigate the application effect of cleaning packaging of surgical medical apparatus and instruments in sterilization and supply center of hospital. Methods The first-time qualification rate of cleaning,packaging and sterility test and incidence rate of nosocomial infection before and after the application of cleaning packaging of surgical medical apparatus and instruments in sterilization and supply center of hospital.The application effect was comprehensively evaluated. Results The first-time qualification rate of cleaning,packaging and sterility test after the application of cleaning packaging of surgical medical apparatus and instruments in sterilization and supply center were significantly increased.The incidence rate of nosocomial infection was 1.5% before and 5.5% after the application of cleaning packaging of surgical medical apparatus and instruments,the difference was significant. Conclusions Application of cleaning packaging of surgical medical apparatus and instruments in sterilization and supply center can effectively control the cleaning and packaging quality,guarantee the thoroughness of subsequent disinfection and sterilization,decrease the incidence rate of nosocomial infection caused by poor quality of surgical medical apparatus and instruments.It creates reliable medical environment for patients and obtain good social and economic benefit,which is worthy of wide application.