In this study Na2HPO4-Ca(NO3)2 system was used to synthesize hydroxyapatite (HA). Its synthetical method was simple and low in cost. With the physical-chemical characteristic observation and the animal experimentit was proved that HA was pure, with pores ranging from 20 to 200 ?m in diameter.The chemical structure of HA was similar to that of inorganic part of bones.An investigation of the histological changes and osteogenetic effectiveness of HA implanted was conducted and the mechanism of HA osteogenetic effectiveness is discussed. The study will provide scientific basis for the clinical use of HA as bone graft substitute.

Pulmonary ventilation function of 22 patients with idiopathic scoliosis was assessed. The results showed that there were significantly lower in Vital Capacity, Vita! Capacity % in predicted, Inspiratory Capacity, Forced Vital Capacity, Forced Expiratory Volume in Is, Maximal Voluntary Ventilation, and Maximal Voluntary Ventilation % in predicted of patients than those of age and sex matched normal controls. And there was no any statistical difference of Tidal Volume, Forced Expiratory Volume in Is % in predicted, Maximal Middle Flow, and Maximal Middle Flow % in predicted between two groups. Furthermore, the reduction of Vital Capacity % in patients with idiopathic scoliosis was correlated with the Cobb Angle, Wedge Index and rotation degree of the top vertebral body and not with the scoliosis direction and the patients' age.

27 rabbits were divided into normal group(n = 4),control group (n = 5), silybin group (n = 6), hyperbaric oxygen (HBO) group (n = 6), and HBO combined with silybin group (n = 6). Circulation of hindlimb was interrupted completely for 6 h and reperfused for 1 h. Malondialdehyde (MDA) and superoxide dismutase(SOD) in plasma from ischemic-reperfused injured limb were measured. Adenosine triphosphate (ATP) and creatine phosphate (CP) in samples taken from anterior tibial muscle were determined. Ultrastructural changes of injured muscle were observed. The results showed that HBO combined with silybin treatment had a favourable effect on ischemic and reperfused injured limb muscle with reduction of the lipid peroxidated injury, increase of the SOD activity and the high energy phosphate compounds (ATP and CP), and a promoting recovery of injured muscle cells. HBO and silybin had a synergistic action. It suggests that HBO combined with silybin is an effective method for treatment of ischemic and reperfused injured limb.

Sciatic neurectomy was performed on the right limb in 30 rats divided into three groups. On the first postoperative days, stainless steel capacitor plates were applied parallel to each other over the midtibial region of the right, neurectomized limb m each animal in the latter two groups, which were stimulated continuously with a 60kHz sinawave signal delivering 5-10V from peak to peak. The first group was served as controls and received no electrical stimulation. At the completion of 12d of electrical stimulation, all rats were sacrificed. A statistically significant enhancement of wet weight, dry weight, ashed weight, ultimate strength and bone density occurred in the stimulated, denervated tibiae of the experimental animals compared with the nonstimulated, denervated tibiae of the control animals. The results show that a sciatic neurectomized osteoporosis was prevented in the tibiae by a capacitively coupled electrical field.