1.Difference between industrial hemp and marijuana hemp and industrial hemp's use value
Yanxu LU ; Peng DONG ; Xiaoguang CUI ; Jianshu GUO ; Yan WANG
Chinese Pharmacological Bulletin 2003;0(08):-
This paper reviewed the classification of hemp,distinction between industrial hemp and marijuana hemp,and the use value of industrial hemp.Some research problems and future research trends were also discussed.
2.Physiological and biochemical reaction of anxiety among individuals with different special characteristics under military stress
Lijie WANG ; Zhaolun DONG ; Jin YAN ; Jun YU ; Jianshu DONG ; Aili LIU
Chinese Journal of Health Management 2010;04(4):210-212
Objective To understand the difference between psychological characteristics and stress response as a result of military stress and to evaluate the rate of stress response among individuals with different psychological characteristics.Methods The State-Trait Anxiety Inventory,blood pressure,breath,pulse wave,and serum levels of lactate acid and cortisol were measured at 8 to 9 am for 372 servicemen following 15 days'training.ResultsIn 97 subjects ,the value of special characteristic anxiety Was 2-standard deviation higher than normal model(i.e.high special characteristic anxiety).and low special characteristic anxiety was found in 79.The condition anxiety of 2 standard deviation higher than normal model wag found in 172 participants.A total of 132 subjects showed significant changes in condition anxiety,serum cortisol and lactic acid,and systolic blood pressure(P<0.01).Sixty-one or 71 subjects with high or low special characteristic anxiety experienced condition anxiety,changed serum cortisol and lactic acid,and systolic blood pressure,respectively.Conclusion Psychological characteristics may be considered as a predicting factor of stress response.
3.Crystal structure of E. coli arginyl-tRNA synthetase and ligand binding studies revealed key residues in arginine recognition.
Kelei BI ; Yueting ZHENG ; Feng GAO ; Jianshu DONG ; Jiangyun WANG ; Yi WANG ; Weimin GONG
Protein & Cell 2014;5(2):151-159
The arginyl-tRNA synthetase (ArgRS) catalyzes the esterification reaction between L-arginine and its cognate tRNA(Arg). Previously reported structures of ArgRS shed considerable light on the tRNA recognition mechanism, while the aspect of amino acid binding in ArgRS remains largely unexplored. Here we report the first crystal structure of E. coli ArgRS (eArgRS) complexed with L-arginine, and a series of mutational studies using isothermal titration calorimetry (ITC). Combined with previously reported work on ArgRS, our results elucidated the structural and functional roles of a series of important residues in the active site, which furthered our understanding of this unique enzyme.
Arginine
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chemistry
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Arginine-tRNA Ligase
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chemistry
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Binding Sites
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Catalytic Domain
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Crystallography, X-Ray
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Escherichia coli
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Ligands
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Mutagenesis, Site-Directed
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Protein Binding
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Protein Conformation
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RNA, Transfer
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chemistry
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Structure-Activity Relationship
4.Advances in biomineralization-inspired materials for hard tissue repair.
Shuxian TANG ; Zhiyun DONG ; Xiang KE ; Jun LUO ; Jianshu LI
International Journal of Oral Science 2021;13(1):42-42
Biomineralization is the process by which organisms form mineralized tissues with hierarchical structures and excellent properties, including the bones and teeth in vertebrates. The underlying mechanisms and pathways of biomineralization provide inspiration for designing and constructing materials to repair hard tissues. In particular, the formation processes of minerals can be partly replicated by utilizing bioinspired artificial materials to mimic the functions of biomolecules or stabilize intermediate mineral phases involved in biomineralization. Here, we review recent advances in biomineralization-inspired materials developed for hard tissue repair. Biomineralization-inspired materials are categorized into different types based on their specific applications, which include bone repair, dentin remineralization, and enamel remineralization. Finally, the advantages and limitations of these materials are summarized, and several perspectives on future directions are discussed.
Biomineralization