Various kinds of scaffold materials are studied and used in cartilage tissue engineering, but none are ideal for the needs of tissue engineering. Mixing different materials together to form a better composite scaffold may brighten the prospect. The present review summarizes the studies of composite materials in cartilage tissue engineering.

Osteogenic protein-1(OP-1),also referred to as bone morphogenetic protein-7(BMP-7),has the effective osteoinduction.In reconstructive surgery of the hip,OP-1 could induce greater and earlier new bone formation,accelerate the incorporation of the graft and host-bone,and enfance the fixation of the plant.The characteristics in the molecular biology and it's application in reconstructive surgery of the hip was reviewed.

Objective To investigate the expression of vascular endothelial growth factor (VEGF)、matrix metalloproteinase-2(MMP-2) and matrix metalloproteinase-9 (MMP-9) in tongue squamous cell carcinoma and the clinical significance.Methods The expression of MMP-2,MMP-9 and VEGF in 60 cases of tongues quamous cell carcinoma tissues and in 20 cases of normal tongues tissues were examined by immunochemistry.Results The expression of MMP-2,MMP-9 and VEGF was higher in tongues quamous cell carcinoma than that in normal pancreatic parenchyma.In cases with lymph nodes metastasis and TNM stage Ⅲ + Ⅳ,the expression of two markers were significantly higher than those without lymph nodes metastasis and TNM stage Ⅰ + Ⅱ (P ＜ 0.05).A positive correlation was found between the expression of VEGF and MMP-2,MMP-9 in tongues quamous cell carcinoma ( P ＜ 0.05 ).Conclusion The expression of MMP-2,MMP-9 and VEGF was closely correlated with lymph nodes metastasis and TNM stage of tongues quamous cell carcinoma(P ＜ 0.05 ).VEGF and MMP-2,MMP-9 play an important role in the development of tongues quamous cell carcinoma,may cooperate with each other.

Objective To investigate the mental health status of adults with human immunodeficiency virus (HIV)infection or acquired immune deficiency syndrome(AIDS).Methods Ninety-four patients with HIV infection or AIDS and 38 healthy subjects were enrolled and filled in the Symptom Checklist 90(SCL-90),Coping Styles Questionnaire(CSQ)and Eysenck Personality Questionnaire(EPQ).Resultsin SCL-90,the scores of compulsion ,depression,anxiety and psychoticism factor were significantly increased in the patient group(all P＜0.05).In the study group,the scores of depression and paranoid ideation factors of male patients were higher than those of female patients.For the participants with HIV infection or AIDS,several factors of SCL-90 were correlative with CSQ and EPQ(r=0.21 to 0.70).ConclusionEmotional disorders may be the most common mental problem of patients with HIV infection or AIDS,and social and psychological supports should be needed.

Early brain injury (EBI) in spontaneous subarachnoid hemorrhage (SAH) plays an important role in prognosis and it become a key target period for clinical treatment and basic research. There were many pathophysiological change in the first few minutes after intracranial aneurysm ruptured. These include increased intracranial pressure (ICP) followed by in?tracranial circulation disorders, calcium overload and sodium, magnesium level fluctuation, ion steady-state disorders in mi?croenviroment of brain cells, serious brain edema due to blood brain barrier (BBB) damage, and changes in other molecules levels, all of which will aggravate SAH. EBI in SAH is one of the important factor that leads to poor prognosis. With the ad?vancement of understanding its pathogenesis, new approach would be available to treat SAH in clinic.

OBJECTIVE:To evaluate the economic effectiveness of different pharmacotherapentic schemes of Prazoles for helicobacteria pylori (Hp) infection. METHODS: 102 patietns with peptic ulcer were randomly assigned to receive Omeprazole +amoxicillin + Colloidal bismmth pectin (Group A), Rabeprazole + Amoxicillin + Colloidal bismmth pectin (Group B) or Rebeprazole + amoxicillin + Colloidal bismmth pectin (Group C). The cost-effectiveness analysis was conducted on the three schemes. RESULTS: The cost-effectiveness ratios of groups A, B and C on Hp clearance rates were 1 027.31, 976.79 and 967.40, respectively, and on peptic ulcer healing rates were 921.05, 915.77 and 936.16, respectively. CONCLUSION: Scheme B is the best one for Hp infection.

Bone loss is often presented in the revision of total hip arthroplasty.The selection of appropriate materials to repair bone deficiency in the revision of total hip arthroplasty requires an understanding of the special bioactivity of the materials.The materials provide the bioactivity of osteogenesis,osteoinduction,osteoconduction and mechanical support.The article give a review of the bioactivity and future applications of the materials in repairing bone deficiency in the revision of total hip arthroplasty.

The idea of using tissue engineering scaffolds in the treatment of spinal cord injury(SCI) is drawing more and more clinical attention,and the introduction of some new materials has promoted its development.Tissue engineering scaffolds used in the treatment of SCI mainly include nature biomaterial and synthesize macromolecule biomaterial,each with its advantages and disadvantages.This review focuses on some tissue engineering scaffolds commonly used in SCI.

Objective To investigate the effect of health education on compliance of the senile non-rheumatic atrial fibrillation patients receiving anticoagulative drug treatment.Methods 188 senile inpatients with on-rheumatic atrial fibrillation and receiving anticoagulative drug treatment were given the health education in three different manners:group instruction,individual instruction and self-study in the hospital for three to four weeks by a team consisted of nurses and doctors.Results After education,the average test scores were higher than before education(P33<0.05).The self-care skill and knowledge such as self-monitor of bleeding were improved.Conclusion Health education is an important method for the senile patients to learn anticoagulative knowledge and improve the ability of self-management.

Tissue engineering technology is a new method to repair articular cartilage defects,and received extensive attention.One of its characters which makes this technology different from a single cell transplantation is the application of scalfold materials.The materials used for scalfold must accord with certain requirements.The previous researches have achieved some break through,but constant improvements still are needed for the alteration from laboratory to clinics.